Murcko scaffold
Ring system with 2 rings and 16 atoms
44 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 44
- With full pages
- 1
Scaffold SMILES
O=C(NCCC1CC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 44 of 44 chemicals
![Ethyl (R)-1-[2-(Cbz-amino)-1-hydroxyethyl]cyclopropane-1-carboxylate chemical structure, C16H21NO5, CAS 328405-08-9](/s/ILXYJKSAPYMMPQ-ZDUSSCGKSA-N.svg)
Ethyl (R)-1-[2-(Cbz-amino)-1-hydroxyethyl]cyclopropane-1-carboxylate
CAS 328405-08-9C16H21NO5
![2-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylpropanoic acid chemical structure, C14H17NO4, CAS 1260642-92-9](/s/NCRLSXDXLQPBEU-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylpropanoic acid
CAS 1260642-92-9C14H17NO4
![(2R)-2-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylpropanoic acid chemical structure, C14H17NO4, CAS 1998579-64-8](/s/NCRLSXDXLQPBEU-GFCCVEGCSA-N.svg)
(2R)-2-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylpropanoic acid
CAS 1998579-64-8C14H17NO4
N-Cbz-(S)-3-cyclopropylalanine
CAS 215523-07-2C14H17NO4
Benzyl N-(2-cyclopropyl-2-hydroxyethyl)carbamate
CAS 1344189-72-5C13H17NO3
![1-(2-{[(Benzyloxy)carbonyl]amino}ethyl)cyclopropane-1-carboxylic acid chemical structure, C14H17NO4, CAS 1935601-15-2](/s/VQQIUMCGDDQBHA-UHFFFAOYSA-N.svg)
1-(2-{[(Benzyloxy)carbonyl]amino}ethyl)cyclopropane-1-carboxylic acid
CAS 1935601-15-2C14H17NO4
Ethyl (2S)-2-(benzyloxycarbonylamino)-3-(1-methylcyclopropyl)propanoate
CAS 1835745-07-7C17H23NO4
Benzyl N-(2-cyclopropyl-2-hydroxypropyl)carbamate
CAS 1877877-14-9C14H19NO3
![Benzyl N-{2-[1-(hydroxymethyl)cyclopropyl]ethyl}carbamate chemical structure, C14H19NO3, CAS 1934891-89-0](/s/OBIYQBWZXYQIQI-UHFFFAOYSA-N.svg)
Benzyl N-{2-[1-(hydroxymethyl)cyclopropyl]ethyl}carbamate
CAS 1934891-89-0C14H19NO3
![Benzyl N-[2-(1-hydroxycyclopropyl)ethyl]carbamate chemical structure, C13H17NO3, CAS 2271472-27-4](/s/BIISICLUAPHALP-UHFFFAOYSA-N.svg)
Benzyl N-[2-(1-hydroxycyclopropyl)ethyl]carbamate
CAS 2271472-27-4C13H17NO3
![rac-2-{[(Benzyloxy)carbonyl]amino}-3-[(1R,2S)-2-ethylcyclopropyl]propanoic acid chemical structure, C16H21NO4, CAS 2227932-39-8](/s/LZYMKRDIGWNKFM-AMIUJLCOSA-N.svg)
rac-2-{[(Benzyloxy)carbonyl]amino}-3-[(1R,2S)-2-ethylcyclopropyl]propanoic acid
CAS 2227932-39-8C16H21NO4
![Benzyl N-[3-(chlorosulfonyl)-2-cyclopropylpropyl]carbamate chemical structure, C14H18ClNO4S, CAS 2172190-66-6](/s/IWMINIHDICHQAD-UHFFFAOYSA-N.svg)
Benzyl N-[3-(chlorosulfonyl)-2-cyclopropylpropyl]carbamate
CAS 2172190-66-6C14H18ClNO4S
![3-{[(Benzyloxy)carbonyl]amino}-4-cyclopropyl-3-methylbutanoic acid chemical structure, C16H21NO4, CAS 2151280-90-7](/s/QKXCUPOXLUZWCW-UHFFFAOYSA-N.svg)
3-{[(Benzyloxy)carbonyl]amino}-4-cyclopropyl-3-methylbutanoic acid
CAS 2151280-90-7C16H21NO4
![2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-difluorocyclopropyl)propanoic acid chemical structure, C14H15F2NO4, CAS 2145433-92-5](/s/DOZAZBIYXXQEHQ-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-difluorocyclopropyl)propanoic acid
CAS 2145433-92-5C14H15F2NO4
![2-{[(Benzyloxy)carbonyl]amino}-3-(1-cyanocyclopropyl)propanoic acid chemical structure, C15H16N2O4, CAS 2156827-84-6](/s/JZPIOYJIMNXKPY-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(1-cyanocyclopropyl)propanoic acid
CAS 2156827-84-6C15H16N2O4
![Benzyl N-(2-{1-[(chlorosulfonyl)methyl]cyclopropyl}ethyl)carbamate chemical structure, C14H18ClNO4S, CAS 2172432-27-6](/s/OQXZLECITLIEDY-UHFFFAOYSA-N.svg)
Benzyl N-(2-{1-[(chlorosulfonyl)methyl]cyclopropyl}ethyl)carbamate
CAS 2172432-27-6C14H18ClNO4S
![Benzyl N-[1-(chlorosulfonyl)-3-cyclopropylpropan-2-yl]carbamate chemical structure, C14H18ClNO4S, CAS 2172117-76-7](/s/NLUHJXYXBCWYGR-UHFFFAOYSA-N.svg)
Benzyl N-[1-(chlorosulfonyl)-3-cyclopropylpropan-2-yl]carbamate
CAS 2172117-76-7C14H18ClNO4S
![2-{[(Benzyloxy)carbonyl]amino}-3-(2-methylcyclopropyl)propanoic acid chemical structure, C15H19NO4, CAS 2156840-40-1](/s/NPGKCMXFAXRGNH-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(2-methylcyclopropyl)propanoic acid
CAS 2156840-40-1C15H19NO4
![2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-difluoro-1-methylcyclopropyl)propanoic acid chemical structure, C15H17F2NO4, CAS 2004099-39-0](/s/SICHQYPTKXLSSC-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-difluoro-1-methylcyclopropyl)propanoic acid
CAS 2004099-39-0C15H17F2NO4
![2-{[(Benzyloxy)carbonyl]amino}-3-[1-(cyanomethyl)cyclopropyl]propanoic acid chemical structure, C16H18N2O4, CAS 2138709-99-4](/s/KARSPPDBSPFNOO-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-[1-(cyanomethyl)cyclopropyl]propanoic acid
CAS 2138709-99-4C16H18N2O4
![2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-dimethylcyclopropyl)propanoic acid chemical structure, C16H21NO4, CAS 2156705-18-7](/s/BAHZPBVLQFIVKA-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-dimethylcyclopropyl)propanoic acid
CAS 2156705-18-7C16H21NO4
![2-{[(Benzyloxy)carbonyl]amino}-3-(2-ethylcyclopropyl)propanoic acid chemical structure, C16H21NO4, CAS 2171461-30-4](/s/LZYMKRDIGWNKFM-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(2-ethylcyclopropyl)propanoic acid
CAS 2171461-30-4C16H21NO4
![4-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylbutanoic acid chemical structure, C15H19NO4, CAS 2164188-43-4](/s/QHRHKUNMMFLLLC-UHFFFAOYSA-N.svg)
4-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylbutanoic acid
CAS 2164188-43-4C15H19NO4
![2-[1-(2-{[(Benzyloxy)carbonyl]amino}ethyl)-2,2-difluorocyclopropyl]acetic acid chemical structure, C15H17F2NO4, CAS 2580227-95-6](/s/SLKNLGWKEMIIKQ-UHFFFAOYSA-N.svg)
2-[1-(2-{[(Benzyloxy)carbonyl]amino}ethyl)-2,2-difluorocyclopropyl]acetic acid
CAS 2580227-95-6C15H17F2NO4
- Benzyl N-[2-hydroxy-2-(1-methylcyclopropyl)ethyl]carbamate2680756-08-3C14H19NO3
- Benzyl N-(1-cyclopropyl-3-hydroxypropan-2-yl)-N-methylcarbamate2680738-41-2C15H21NO3
- Benzyl N-[2-(2,2-dichloro-1-methylcyclopropyl)ethyl]carbamate2680721-79-1C14H17Cl2NO2
- Benzyl N-(2-cyclopropyl-2-hydroxyethyl)-N-methylcarbamate2151382-56-6C14H19NO3
- Benzyl N-(2-cyclopropyl-3-hydroxypropyl)carbamate2294123-32-1C14H19NO3
- Benzyl N-(2-cyclopropylpent-4-yn-1-yl)carbamate2680678-67-3C16H19NO2
- Benzyl N-[2-(2-chloro-2-fluoro-1-methylcyclopropyl)ethyl]carbamate2680851-80-1C14H17ClFNO2
- 2-{[(Benzyloxy)carbonyl]amino}-3-cyclopropylbutanoic acid2680546-56-7C15H19NO4
- Benzyl N-(1-cyclopropylbut-3-yn-2-yl)carbamate2680787-01-1C15H17NO2
- Benzyl N-[2-(1-chlorocyclopropyl)-2-hydroxyethyl]carbamate2680848-54-6C13H16ClNO3
- (2S)-2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-difluorocyclopropyl)propanoic acid2680522-88-5C14H15F2NO4
- Benzyl N-(1-cyclopropyl-3-hydroxypropan-2-yl)carbamate2303408-12-8C14H19NO3
- Benzyl N-[2-(2,2-dibromocyclopropyl)ethyl]carbamate2680705-80-8C13H15Br2NO2
- Benzyl N-[2-(2,2-dichlorocyclopropyl)ethyl]carbamate2680888-02-0C13H15Cl2NO2
- 2-{[(Benzyloxy)carbonyl]amino}-3-(1-methylcyclopropyl)propanoic acid2352068-20-1C15H19NO4
- (2R)-2-{[(Benzyloxy)carbonyl]amino}-3-(2,2-difluorocyclopropyl)propanoic acid2770475-10-8C14H15F2NO4
- 2-(2-{[(Benzyloxy)carbonyl]amino}-3-hydroxypropyl)cyclopropane-1-carboxylic acid2359536-84-6C15H19NO5
- Ethyl 2-(benzyloxycarbonylamino)-3-(1-methylcyclopropyl)propanoate2755952-40-8C17H23NO4
- rac-(1R,2S)-2-(2-{[(Benzyloxy)carbonyl]amino}ethyl)cyclopropane-1-carboxylic acid2350517-85-8C14H17NO4
- Ethyl (2R)-2-(benzyloxycarbonylamino)-3-(1-methylcyclopropyl)propanoate2891580-53-1C17H23NO4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCCc1ccccc1)C(=O)NC1CC14 chemicals
O=C(COC(=O)c1ccccc1)NCC1CC12 chemicals
O=C(COC(=O)C1CC1)NC(=O)c1ccccc12 chemicals
O=C(OCCOCC1CCCCC1)C1CC11 chemical
C(C=CC1CCCCO1)=CCCC1CO11 chemical
c1ccc(OCCCCCC2CO2)cc11 chemical
S=C(NCCCN1CCOCC1)NC1CC11 chemical
O=C(COc1ccccc1)NNC(=O)C1CC11 chemical
O=C(CSC=Nc1ccccc1)NC1CC11 chemical
C(=CCOc1ccccc1)CCC1CO11 chemical
O=C(CCNCC1CC1)Nc1ccccc11 chemical
O=C(CCC1CC1)NCCc1ccccc11 chemical