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Murcko scaffold

1H-Benzo[d]azepin-2(3H)-one scaffold

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
24
With full pages
4
Scaffold SMILES

O=C1Cc2ccccc2C=CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Benzo[d]azepin-2(3H)-one page
Murcko scaffold O=C1Cc2ccccc2C=CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one chemical structure, C12H13NO3, CAS 73942-87-7
1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one
CAS 73942-87-7C12H13NO3
1H-Benzo[d]azepin-2(3H)-one chemical structure, C10H9NO, CAS 19301-09-8
1H-Benzo[d]azepin-2(3H)-one
CAS 19301-09-8C10H9NO
8-Methoxy-2,3-dihydro-1H-3-benzazepin-2-one chemical structure, C11H11NO2, CAS 85175-85-5
8-Methoxy-2,3-dihydro-1H-3-benzazepin-2-one
CAS 85175-85-5C11H11NO2
3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one chemical structure, C15H18ClNO3, CAS 85175-59-3
3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one
CAS 85175-59-3C15H18ClNO3
1,3-Dihydro-3-(3-iodopropyl)-7,8-dimethoxy-2H-3-benzazepin-2-one chemical structure, C15H18INO3, CAS 148870-57-9
1,3-Dihydro-3-(3-iodopropyl)-7,8-dimethoxy-2H-3-benzazepin-2-one
CAS 148870-57-9C15H18INO3
3-(4-Chlorobut-2-EN-1-yl)-7,8-dimethoxy-1H-benzo[D]azepin-2(3H)-one chemical structure, C16H18ClNO3, CAS 2797049-42-2
3-(4-Chlorobut-2-EN-1-yl)-7,8-dimethoxy-1H-benzo[D]azepin-2(3H)-one
CAS 2797049-42-2C16H18ClNO3
8-Methoxy-1-methyl-2,3-dihydro-1H-3-benzazepin-2-one chemical structure, C12H13NO2, CAS 952710-33-7
8-Methoxy-1-methyl-2,3-dihydro-1H-3-benzazepin-2-one
CAS 952710-33-7C12H13NO2
8-Methoxy-3-methyl-2,3-dihydro-1H-3-benzazepin-2-one chemical structure, C12H13NO2, CAS 120039-18-1
8-Methoxy-3-methyl-2,3-dihydro-1H-3-benzazepin-2-one
CAS 120039-18-1C12H13NO2
3-Methyl-2,3-dihydro-1H-3-benzazepin-2-one chemical structure, C11H11NO, CAS 425386-56-7
3-Methyl-2,3-dihydro-1H-3-benzazepin-2-one
CAS 425386-56-7C11H11NO
3-(3,3-Dimethyl-2-oxobutyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one chemical structure, C18H23NO4, CAS 1574365-54-0
3-(3,3-Dimethyl-2-oxobutyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
CAS 1574365-54-0C18H23NO4
Isopropyl 2-(7,8-dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)acetate chemical structure, C17H21NO5, CAS 1574365-33-5
Isopropyl 2-(7,8-dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)acetate
CAS 1574365-33-5C17H21NO5
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-(3-methylbutyl)acetamide chemical structure, C19H26N2O4, CAS 1574405-88-1
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-(3-methylbutyl)acetamide
CAS 1574405-88-1C19H26N2O4
(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)acetic acid chemical structure, C14H15NO5, CAS 1573547-27-9
(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)acetic acid
CAS 1573547-27-9C14H15NO5
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-(prop-2-en-1-yl)acetamide chemical structure, C17H20N2O4, CAS 1574351-16-8
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-(prop-2-en-1-yl)acetamide
CAS 1574351-16-8C17H20N2O4
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-(heptan-2-yl)acetamide chemical structure, C21H30N2O4, CAS 1574354-02-1
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-(heptan-2-yl)acetamide
CAS 1574354-02-1C21H30N2O4
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-pentylacetamide chemical structure, C19H26N2O4, CAS 1574351-14-6
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-pentylacetamide
CAS 1574351-14-6C19H26N2O4
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-[3-(propan-2-yloxy)propyl]acetamide chemical structure, C20H28N2O5, CAS 1574292-46-8
2-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)-N-[3-(propan-2-yloxy)propyl]acetamide
CAS 1574292-46-8C20H28N2O5
3-(3-Hydroxypropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one chemical structure, C15H19NO4, CAS 1235547-06-4
3-(3-Hydroxypropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one
CAS 1235547-06-4C15H19NO4
8-Hydroxy-7-methoxy-1,3-dihydro-henzo[d]azepin-2-one chemical structure, C11H11NO3, CAS 1824185-67-2
8-Hydroxy-7-methoxy-1,3-dihydro-henzo[d]azepin-2-one
CAS 1824185-67-2C11H11NO3
3-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)propanoic acid chemical structure, C15H17NO5, CAS 1674390-14-7
3-(7,8-Dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)propanoic acid
CAS 1674390-14-7C15H17NO5
(E)-3-(4-Chlorobut-2-en-1-yl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one chemical structure, C16H18ClNO3, CAS 847737-94-4
(E)-3-(4-Chlorobut-2-en-1-yl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one
CAS 847737-94-4C16H18ClNO3
7-Methoxy-1H-benzo[d]azepin-2(3H)-one chemical structure, C11H11NO2, CAS 1824250-38-5
7-Methoxy-1H-benzo[d]azepin-2(3H)-one
CAS 1824250-38-5C11H11NO2
Ivabradine impurity 1 chemical structure, C15H18BrNO3, CAS 1428869-91-3
Ivabradine impurity 1
CAS 1428869-91-3C15H18BrNO3
5-Bromo-1,3-dihydro-2H-benzo[d]azepin-2-one chemical structure, C10H8BrNO, CAS 19301-14-5
5-Bromo-1,3-dihydro-2H-benzo[d]azepin-2-one
CAS 19301-14-5C10H8BrNO