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Murcko scaffold

Ring system with 4 rings and 22 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
17
With full pages
0
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CNc2nc3ccccc3nc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CNc2nc3ccccc3nc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-((4-Chlorophenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C19H19ClN4O3S, CAS 846594-03-4
1-((4-Chlorophenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 846594-03-4C19H19ClN4O3S
1-((3-Chlorophenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C19H19ClN4O3S, CAS 847335-95-9
1-((3-Chlorophenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 847335-95-9C19H19ClN4O3S
1-((4-Chlorophenyl)sulfonyl)-3-(2-methoxyethyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C18H17ClN4O3S, CAS 847368-89-2
1-((4-Chlorophenyl)sulfonyl)-3-(2-methoxyethyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 847368-89-2C18H17ClN4O3S
1-Allyl-3-((3-chlorophenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C18H15ClN4O2S, CAS 847369-23-7
1-Allyl-3-((3-chlorophenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 847369-23-7C18H15ClN4O2S
1-Butyl-3-((3-chlorophenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C19H19ClN4O2S, CAS 844447-75-2
1-Butyl-3-((3-chlorophenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 844447-75-2C19H19ClN4O2S
1-Isopentyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C21H24N4O3S, CAS 844832-77-5
1-Isopentyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 844832-77-5C21H24N4O3S
1-((4-Chlorophenyl)sulfonyl)-3-(3-isopropoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C21H23ClN4O3S, CAS 848058-39-9
1-((4-Chlorophenyl)sulfonyl)-3-(3-isopropoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848058-39-9C21H23ClN4O3S
1-((4-Methoxyphenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C20H22N4O4S, CAS 848205-46-9
1-((4-Methoxyphenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848205-46-9C20H22N4O4S
1-Isobutyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C20H22N4O3S, CAS 848216-79-5
1-Isobutyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848216-79-5C20H22N4O3S
1-((2,4-Dimethylphenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C21H24N4O3S, CAS 848681-80-1
1-((2,4-Dimethylphenyl)sulfonyl)-3-(3-methoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848681-80-1C21H24N4O3S
1-((3-Chlorophenyl)sulfonyl)-3-(2-methoxyethyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C18H17ClN4O3S, CAS 848687-52-5
1-((3-Chlorophenyl)sulfonyl)-3-(2-methoxyethyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848687-52-5C18H17ClN4O3S
1-((4-Chlorophenyl)sulfonyl)-3-(3-ethoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C20H21ClN4O3S, CAS 848755-28-2
1-((4-Chlorophenyl)sulfonyl)-3-(3-ethoxypropyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848755-28-2C20H21ClN4O3S
1-(3,4-Dimethylbenzenesulfonyl)-3-(2-methylpropyl)-1H,2H,3H-imidazo[4,5-b]quinoxaline chemical structure, C21H24N4O2S, CAS 850902-63-5
1-(3,4-Dimethylbenzenesulfonyl)-3-(2-methylpropyl)-1H,2H,3H-imidazo[4,5-b]quinoxaline
CAS 850902-63-5C21H24N4O2S
1-Pentyl-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C20H22N4O2S, CAS 881565-18-0
1-Pentyl-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 881565-18-0C20H22N4O2S
1-Butan-2-yl-3-(4-chlorophenyl)sulfonyl-2H-imidazo[4,5-b]quinoxaline chemical structure, C19H19ClN4O2S, CAS 847037-81-4
1-Butan-2-yl-3-(4-chlorophenyl)sulfonyl-2H-imidazo[4,5-b]quinoxaline
CAS 847037-81-4C19H19ClN4O2S
1-((3,4-Dimethylphenyl)sulfonyl)-3-(2-methoxyethyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C20H22N4O3S, CAS 847035-88-5
1-((3,4-Dimethylphenyl)sulfonyl)-3-(2-methoxyethyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 847035-88-5C20H22N4O3S
1-Allyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C19H18N4O3S, CAS 844650-15-3
1-Allyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 844650-15-3C19H18N4O3S