Murcko scaffold
Ring system with 4 rings and 22 atoms
10 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 10
- With full pages
- 0
Scaffold SMILES
O=c1c2ccccc2cc(N2CCNCC2)c2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
5H-Dibenzo(a,d)cyclohepten-5-one, 10-(4-isopropyl-1-piperazinyl)-
CAS 16270-56-7C22H24N2O
5H-Dibenzo(a,d)cyclohepten-5-one, chloro-10-(4-methyl-1-piperazinyl)-
CAS 56958-43-1C20H19ClN2O
Rmi 61214
CAS 56972-88-4C23H22N2O3
Rmi 61,218
CAS 56972-89-5C21H20N2O3
Rmi 61211
CAS 56972-94-2C22H23N3O2
Rmi 61196
CAS 56972-96-4C24H25N3O4
Rmi 61,195
CAS 56972-97-5C24H27N3O2
Rmi 61193
CAS 56973-01-4C23H25N3O2
Rmi 61,143
CAS 56973-02-5C22H23N3O2
Clozapine analogues
CAS 124380-97-8C20H19ClN2O