CompoundList
Sign in
Murcko scaffold

2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1Cn2c(nc3ccccc3c2=O)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione page
Murcko scaffold O=C1Cn2c(nc3ccccc3c2=O)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1-Methyl-2-pentyl-2H-pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione chemical structure, C17H21N3O2, CAS 866010-14-2
1-Methyl-2-pentyl-2H-pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione
CAS 866010-14-2C17H21N3O2
2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione, 1-methyl-, (1S)- chemical structure, C12H11N3O2, CAS 437768-88-2
2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione, 1-methyl-, (1S)-
CAS 437768-88-2C12H11N3O2
2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione chemical structure, C11H9N3O2, CAS 651043-51-5
2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione
CAS 651043-51-5C11H9N3O2
(S,S)-Anacine chemical structure, C18H22N4O3, CAS 154613-22-6
(S,S)-Anacine
CAS 154613-22-6C18H22N4O3
Aurantiomide B chemical structure, C18H22N4O4, CAS 915190-84-0
Aurantiomide B
CAS 915190-84-0C18H22N4O4
Aurantiomide A chemical structure, C19H24N4O4, CAS 915190-85-1
Aurantiomide A
CAS 915190-85-1C19H24N4O4