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Murcko scaffold

Ring system with 3 rings and 14 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
8
With full pages
1
Scaffold SMILES

c1nc(C2CC2)ncc1B1OCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(C2CC2)ncc1B1OCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine chemical structure, C13H19BN2O2, CAS 1375301-91-9
2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
CAS 1375301-91-9C13H19BN2O2
2-Cyclopropyl-4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine chemical structure, C14H21BN2O2, CAS 1951411-52-1
2-Cyclopropyl-4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
CAS 1951411-52-1C14H21BN2O2
4-Chloro-2-(cyclopropyl)pyrimidine-5-boronic acid pinacol ester chemical structure, C13H18BClN2O2, CAS 2223027-68-5
4-Chloro-2-(cyclopropyl)pyrimidine-5-boronic acid pinacol ester
CAS 2223027-68-5C13H18BClN2O2
1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)cyclopropane-1-carbonitrile chemical structure, C14H18BN3O2, CAS 2962795-80-6
1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)cyclopropane-1-carbonitrile
CAS 2962795-80-6C14H18BN3O2
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine chemical structure, C13H19BN2O2, CAS 2241866-01-1
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
CAS 2241866-01-1C13H19BN2O2
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-4,6-d2 chemical structure, C13H19BN2O2, CAS 2241866-00-0
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-4,6-d2
CAS 2241866-00-0C13H19BN2O2
2-(2,2-Difluorocyclopropyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine chemical structure, C13H17BF2N2O2, CAS 2710293-81-3
2-(2,2-Difluorocyclopropyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
CAS 2710293-81-3C13H17BF2N2O2
tert-Butyl N-{1-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]cyclopropyl}carbamate chemical structure, C18H28BN3O4, CAS 2611424-69-0
tert-Butyl N-{1-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]cyclopropyl}carbamate
CAS 2611424-69-0C18H28BN3O4