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Murcko scaffold

Ring system with 3 rings and 17 atoms

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
33
With full pages
5
Scaffold SMILES

O=c1cc[nH]c2nc(N3CCNCC3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc[nH]c2nc(N3CCNCC3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

Enoxacin chemical structure, C15H17FN4O3, CAS 74011-58-8
Enoxacin
CAS 74011-58-8C15H17FN4O3
1-tert-Butyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C18H23FN4O3, CAS 116162-95-9
1-tert-Butyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 116162-95-9C18H23FN4O3
1-tert-Butyl-7-(3,5-dimethyl-piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-(1,8)naphthyridine-3-carboxylic acid chemical structure, C19H25FN4O3, CAS 182868-99-1
1-tert-Butyl-7-(3,5-dimethyl-piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-(1,8)naphthyridine-3-carboxylic acid
CAS 182868-99-1C19H25FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-(1,1-dimethylethyl)-6-fluoro-4-oxo-7-(1-piperazinyl)- chemical structure, C17H21FN4O3, CAS 116162-91-5
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-(1,1-dimethylethyl)-6-fluoro-4-oxo-7-(1-piperazinyl)-
CAS 116162-91-5C17H21FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1-(1,1-dimethylethyl)-7-(3-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C19H25FN4O3, CAS 183135-60-6
1,8-Naphthyridine-3-carboxylic acid, 1-(1,1-dimethylethyl)-7-(3-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 183135-60-6C19H25FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1-(1,1-dimethylethyl)-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C19H25FN4O3, CAS 182869-01-8
1,8-Naphthyridine-3-carboxylic acid, 1-(1,1-dimethylethyl)-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 182869-01-8C19H25FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo- chemical structure, C16H19FN4O3, CAS 100505-13-3
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
CAS 100505-13-3C16H19FN4O3
1,8-Naphthyridine-3-carboxylic acid, 7-(3,5-dimethyl-1-piperazinyl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C17H21FN4O3, CAS 182868-92-4
1,8-Naphthyridine-3-carboxylic acid, 7-(3,5-dimethyl-1-piperazinyl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-
CAS 182868-92-4C17H21FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C17H21FN4O3, CAS 74274-67-2
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 74274-67-2C17H21FN4O3
1-tert-Butyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C18H23FN4O3, CAS 125197-41-3
1-tert-Butyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 125197-41-3C18H23FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-chloro-1-ethyl-4-oxo-7-(1-piperazinyl)-, monohydrochloride chemical structure, C15H18Cl2N4O3, CAS 74274-59-2
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-chloro-1-ethyl-4-oxo-7-(1-piperazinyl)-, monohydrochloride
CAS 74274-59-2C15H18Cl2N4O3
1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C16H19FN4O3, CAS 74274-66-1
1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 74274-66-1C16H19FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethenyl-6-fluoro-4-oxo-7-(1-piperazinyl)- chemical structure, C15H15FN4O3, CAS 74274-71-8
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethenyl-6-fluoro-4-oxo-7-(1-piperazinyl)-
CAS 74274-71-8C15H15FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-7-(4-methyl-1-piperazinyl)-1-vinyl-4-oxo- chemical structure, C16H17FN4O3, CAS 74274-72-9
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-7-(4-methyl-1-piperazinyl)-1-vinyl-4-oxo-
CAS 74274-72-9C16H17FN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-, monomethanesulfonate chemical structure, C16H21FN4O6S, CAS 75167-06-5
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-, monomethanesulfonate
CAS 75167-06-5C16H21FN4O6S
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethenyl-6-fluoro-4-oxo-7-(1-piperazinyl)-,monohydrochloride chemical structure, C15H16ClFN4O3, CAS 75167-16-7
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethenyl-6-fluoro-4-oxo-7-(1-piperazinyl)-,monohydrochloride
CAS 75167-16-7C15H16ClFN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-chloro-1-ethenyl-4-oxo-7-(1-piperazinyl)- chemical structure, C15H15ClN4O3, CAS 75167-20-3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-chloro-1-ethenyl-4-oxo-7-(1-piperazinyl)-
CAS 75167-20-3C15H15ClN4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo- chemical structure, C16H18F2N4O3, CAS 84209-33-6
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-
CAS 84209-33-6C16H18F2N4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroethyl)-4-oxo-7-(1-piperazinyl)- chemical structure, C15H16F2N4O3, CAS 84209-34-7
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroethyl)-4-oxo-7-(1-piperazinyl)-
CAS 84209-34-7C15H16F2N4O3
1-Ethyl-6-fluoro-7-(1-piperazinyl)-1,8-naphthyridin-4(1H)-one chemical structure, C14H17FN4O, CAS 106692-39-1
1-Ethyl-6-fluoro-7-(1-piperazinyl)-1,8-naphthyridin-4(1H)-one
CAS 106692-39-1C14H17FN4O
Enoxacin impurity 8 chemical structure, C14H15FN4O3, CAS 115274-26-5
Enoxacin impurity 8
CAS 115274-26-5C14H15FN4O3
Ethyl 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate chemical structure, C17H21FN4O3, CAS 74011-30-6
Ethyl 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS 74011-30-6C17H21FN4O3
Ethyl 7-(4-acetyl-1-piperazinyl)-6-F-4-hydroxy(1,8)naphthyridine-3-carboxylate chemical structure, C17H19FN4O4, CAS 882865-15-8
Ethyl 7-(4-acetyl-1-piperazinyl)-6-F-4-hydroxy(1,8)naphthyridine-3-carboxylate
CAS 882865-15-8C17H19FN4O4
7-(4-Acetylpiperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid chemical structure, C17H19FN4O4, CAS 74274-70-7
7-(4-Acetylpiperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
CAS 74274-70-7C17H19FN4O4