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Murcko scaffold

Ring system with 3 rings and 15 atoms

36 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 15
Chemicals: 36
With full pages: 13

Scaffold SMILES

O=C1NCc2cncn2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1NCc2cncn2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

Flumazenil chemical structure, C15H14FN3O3, CAS 78755-81-4

CAS 78755-81-4C₁₅H₁₄FN₃O₃

Ethyl 8-azido-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate chemical structure, C15H14N6O3, CAS 91917-65-6

Ethyl 8-azido-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

CAS 91917-65-6C₁₅H₁₄N₆O₃

Iomazenil (123I) chemical structure, C15H14IN3O3, CAS 127396-36-5

Iomazenil (123I)

CAS 127396-36-5C₁₅H₁₄IN₃O₃

Sarmazenil chemical structure, C15H14ClN3O3, CAS 78771-13-8

CAS 78771-13-8C₁₅H₁₄ClN₃O₃

Ro 15-3505 chemical structure, C15H14ClN3O3, CAS 78756-33-9

CAS 78756-33-9C₁₅H₁₄ClN₃O₃

Fluoroethylflumazenil F-18 chemical structure, C16H15F2N3O3, CAS 143693-57-6

Fluoroethylflumazenil F-18

CAS 143693-57-6C₁₆H₁₅F₂N₃O₃

Ro 14-7437 chemical structure, C15H15N3O3, CAS 78756-03-3

CAS 78756-03-3C₁₅H₁₅N₃O₃

Ethyl 8-fluoro-5,6-dihydro-5-(3'-fluoropropyl)-6-oxo-4H-imidazol(1,5-a)(1,4)benzodiazepine-3-carboxylate chemical structure, C17H17F2N3O3, CAS 133368-71-5

Ethyl 8-fluoro-5,6-dihydro-5-(3'-fluoropropyl)-6-oxo-4H-imidazol(1,5-a)(1,4)benzodiazepine-3-carboxylate

CAS 133368-71-5C₁₇H₁₇F₂N₃O₃

3'-Fluoropropyl-8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazol(1,5-a)(1,4)benzodiazepine-3-carboxylic acid chemical structure, C16H15F2N3O3, CAS 133368-73-7

3'-Fluoropropyl-8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazol(1,5-a)(1,4)benzodiazepine-3-carboxylic acid

CAS 133368-73-7C₁₆H₁₅F₂N₃O₃

Ro 15-3890 chemical structure, C13H10FN3O3, CAS 84378-44-9

CAS 84378-44-9C₁₃H₁₀FN₃O₃

ZG 63 chemical structure, C17H18ClN3O3, CAS 146137-59-9

CAS 146137-59-9C₁₇H₁₈ClN₃O₃

Flumazenil C-11 chemical structure, C15H14FN3O3, CAS 92745-42-1

Flumazenil C-11

CAS 92745-42-1C₁₅H₁₄FN₃O₃

N-Desmethylflumazenil chemical structure, C14H12FN3O3, CAS 79089-72-8

N-Desmethylflumazenil

CAS 79089-72-8C₁₄H₁₂FN₃O₃

RY 024 chemical structure, C19H19N3O3, CAS 173990-15-3

CAS 173990-15-3C₁₉H₁₉N₃O₃

Pwz-029 chemical structure, C14H14ClN3O2, CAS 164025-33-6

CAS 164025-33-6C₁₄H₁₄ClN₃O₂

Iomazenil chemical structure, C15H14IN3O3, CAS 127985-21-1

CAS 127985-21-1C₁₅H₁₄IN₃O₃

Ethyl 8-bromo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate chemical structure, C15H14BrN3O3, CAS 78756-37-3

Ethyl 8-bromo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate

CAS 78756-37-3C₁₅H₁₄BrN₃O₃

Flumazenil F-18 chemical structure, C15H14FN3O3, CAS 790234-73-0

Flumazenil F-18

CAS 790234-73-0C₁₅H₁₄FN₃O₃

8-Fluoro-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid chemical structure, C12H8FN3O3, CAS 118024-85-4

8-Fluoro-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid

CAS 118024-85-4C₁₂H₈FN₃O₃

Ethyl 7-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate chemical structure, C15H14FN3O3, CAS 78755-96-1

Ethyl 7-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

CAS 78755-96-1C₁₅H₁₄FN₃O₃

7-Chloro-N'-hydroxy-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboximidamide chemical structure, C13H12ClN5O2, CAS 106937-65-9

7-Chloro-N'-hydroxy-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboximidamide

CAS 106937-65-9C₁₃H₁₂ClN₅O₂

Ethyl 5-methyl-8-nitro-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate chemical structure, C15H14N4O5, CAS 84377-97-9

Ethyl 5-methyl-8-nitro-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

CAS 84377-97-9C₁₅H₁₄N₄O₅

Ethyl-5,6-dihydro-5,7-dimethyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate chemical structure, C16H17N3O3, CAS 78756-20-4

Ethyl-5,6-dihydro-5,7-dimethyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

CAS 78756-20-4C₁₆H₁₇N₃O₃

7-Fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid chemical structure, C13H10FN3O3, CAS 99622-49-8

7-Fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid

CAS 99622-49-8C₁₃H₁₀FN₃O₃