CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 37 atoms

5 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
37
Chemicals
5
With full pages
5
Scaffold SMILES

O=C(OCc1ccccc1)C1=CNC=C(C(=O)OCc2ccccc2)C1c1ccc(-c2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCc1ccccc1)C1=CNC=C(C(=O)OCc2ccccc2)C1c1ccc(-c2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Dibenzyl 2,6-dimethyl-4-[5-(2-nitrophenyl)-2-furyl]-1,4-dihydro-3,5-pyridinedicarboxylate chemical structure, C33H28N2O7, CAS 312938-39-9
Dibenzyl 2,6-dimethyl-4-[5-(2-nitrophenyl)-2-furyl]-1,4-dihydro-3,5-pyridinedicarboxylate
CAS 312938-39-9C33H28N2O7
Dibenzyl 4-(5-(4-chlorophenyl)-2-furyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate chemical structure, C33H28ClNO5, CAS 421580-73-6
Dibenzyl 4-(5-(4-chlorophenyl)-2-furyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
CAS 421580-73-6C33H28ClNO5
Dibenzyl 2,6-dimethyl-4-(5-(3-nitrophenyl)-2-furyl)-1,4-dihydro-3,5-pyridinedicarboxylate chemical structure, C33H28N2O7, CAS 421580-74-7
Dibenzyl 2,6-dimethyl-4-(5-(3-nitrophenyl)-2-furyl)-1,4-dihydro-3,5-pyridinedicarboxylate
CAS 421580-74-7C33H28N2O7
Dibenzyl 4-[5-(2,4-dichlorophenyl)-2-furyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate chemical structure, C33H27Cl2NO5, CAS 421580-72-5
Dibenzyl 4-[5-(2,4-dichlorophenyl)-2-furyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
CAS 421580-72-5C33H27Cl2NO5
Dibenzyl 4-[5-(2,5-dichlorophenyl)-2-furyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate chemical structure, C33H27Cl2NO5, CAS 421580-75-8
Dibenzyl 4-[5-(2,5-dichlorophenyl)-2-furyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
CAS 421580-75-8C33H27Cl2NO5