Murcko scaffold
2-Oxo-N-phenylhexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide scaffold
44 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 19
- Chemicals
- 44
- With full pages
- 5
Scaffold SMILES
O=C(Nc1ccccc1)C1C2CC3OC(=O)C1C3C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 44 of 44 chemicals
![2-Oxo-N-phenylhexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H15NO3, CAS 855840-69-6](/s/XVZVHBKIVGUKRA-UHFFFAOYSA-N.svg)
2-Oxo-N-phenylhexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 855840-69-6C15H15NO3
![N-(4-Methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H17NO3, CAS 1005150-73-1](/s/KNEJBUOSBFPCIE-UHFFFAOYSA-N.svg)
N-(4-Methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005150-73-1C16H17NO3
![N-(3-Chloro-4-methylphenyl)-5-oxo-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide chemical structure, C16H16ClNO3, CAS 1005122-29-1](/s/DBAPOUONWZJLLU-UHFFFAOYSA-N.svg)
N-(3-Chloro-4-methylphenyl)-5-oxo-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide
CAS 1005122-29-1C16H16ClNO3
![Isopropyl 4-{[(5-oxo-4-oxatricyclo[4.2.1.0~3,7~]non-9-yl)carbonyl]amino}benzoate chemical structure, C19H21NO5, CAS 1005151-40-5](/s/LLBUIDYEVHXNFM-UHFFFAOYSA-N.svg)
Isopropyl 4-{[(5-oxo-4-oxatricyclo[4.2.1.0~3,7~]non-9-yl)carbonyl]amino}benzoate
CAS 1005151-40-5C19H21NO5
![N-(4-Chlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H14ClNO3, CAS 1005122-26-8](/s/KUXWSBMWFVMCNR-UHFFFAOYSA-N.svg)
N-(4-Chlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005122-26-8C15H14ClNO3
![N-(4-Ethoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C17H19NO4, CAS 1005122-66-6](/s/IOFUFMMFEROPMG-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005122-66-6C17H19NO4
![N-(4-Fluorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H14FNO3, CAS 1005281-57-1](/s/RCMPDKQHHLGASK-UHFFFAOYSA-N.svg)
N-(4-Fluorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005281-57-1C15H14FNO3
![N-(4-Bromo-5-chloro-2-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H15BrClNO3, CAS 1005123-03-4](/s/BTAXHRMUPDJBLR-UHFFFAOYSA-N.svg)
N-(4-Bromo-5-chloro-2-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005123-03-4C16H15BrClNO3
![N-(2,5-Dimethoxyphenyl)-5-oxo-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide chemical structure, C17H19NO5, CAS 1005281-34-4](/s/YCXQFNKUNUIKKV-UHFFFAOYSA-N.svg)
N-(2,5-Dimethoxyphenyl)-5-oxo-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide
CAS 1005281-34-4C17H19NO5
![N-(3-Nitrophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H14N2O5, CAS 1005281-46-8](/s/UHCXMHUYYNWACA-UHFFFAOYSA-N.svg)
N-(3-Nitrophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005281-46-8C15H14N2O5
![N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H13ClF3NO3, CAS 1005281-45-7](/s/MPJINENFQNGJBG-UHFFFAOYSA-N.svg)
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005281-45-7C16H13ClF3NO3
![N-(4-Iodophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H14INO3, CAS 1001166-22-8](/s/AGIHJRKHMINQHJ-UHFFFAOYSA-N.svg)
N-(4-Iodophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1001166-22-8C15H14INO3
![N-(4-Bromophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H14BrNO3, CAS 1005122-32-6](/s/OTLAUPLOUOONEL-UHFFFAOYSA-N.svg)
N-(4-Bromophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005122-32-6C15H14BrNO3
![N-(5-Chloro-2-methoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H16ClNO4, CAS 1005122-39-3](/s/BACVXVJEIMVFFX-UHFFFAOYSA-N.svg)
N-(5-Chloro-2-methoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005122-39-3C16H16ClNO4
![N-(3,4-Dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H13Cl2NO3, CAS 1005108-42-8](/s/RGXSOEPUPIOTCA-UHFFFAOYSA-N.svg)
N-(3,4-Dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005108-42-8C15H13Cl2NO3
![N-(4-Bromo-2,3-dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C17H18BrNO3, CAS 1005127-59-2](/s/SNZOZEUILLVFRY-UHFFFAOYSA-N.svg)
N-(4-Bromo-2,3-dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005127-59-2C17H18BrNO3
![N-(3-Methoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H17NO4, CAS 1005127-26-3](/s/NXUUHKMQIPGSQF-UHFFFAOYSA-N.svg)
N-(3-Methoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005127-26-3C16H17NO4
![N-(4-Methyl-3-nitrophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H16N2O5, CAS 1005127-66-1](/s/YIFNJDUNMROQMD-UHFFFAOYSA-N.svg)
N-(4-Methyl-3-nitrophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005127-66-1C16H16N2O5
![N-(4-Nitrophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H14N2O5, CAS 1005108-58-6](/s/UISPVILPNWSMGC-UHFFFAOYSA-N.svg)
N-(4-Nitrophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005108-58-6C15H14N2O5
![N-(2,4-Dimethoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C17H19NO5, CAS 1005127-16-1](/s/MWDYKHNXLCGCKQ-UHFFFAOYSA-N.svg)
N-(2,4-Dimethoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005127-16-1C17H19NO5
![5-Oxo-N-[3-(trifluoromethyl)phenyl]-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide chemical structure, C16H14F3NO3, CAS 1005127-46-7](/s/GZIYDTRUFINXAO-UHFFFAOYSA-N.svg)
5-Oxo-N-[3-(trifluoromethyl)phenyl]-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide
CAS 1005127-46-7C16H14F3NO3
![N-(2,5-Dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H13Cl2NO3, CAS 1005060-44-5](/s/PQAPAWQZVJQZTA-UHFFFAOYSA-N.svg)
N-(2,5-Dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005060-44-5C15H13Cl2NO3
![N-(2,4-Dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C15H13Cl2NO3, CAS 1005060-50-3](/s/UIHWEAKKVMGISS-UHFFFAOYSA-N.svg)
N-(2,4-Dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005060-50-3C15H13Cl2NO3
![N-(4-Bromo-2-methoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide chemical structure, C16H16BrNO4, CAS 1005094-88-1](/s/JSIHZHKCOSRVTO-UHFFFAOYSA-N.svg)
N-(4-Bromo-2-methoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide
CAS 1005094-88-1C16H16BrNO4
- N-(4-Bromo-2,6-dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005094-82-5C17H18BrNO3
- 2-Bromo-N-(4-methylphenyl)-5-oxo-4-oxatricyclo[4.2.1.0~3,7~]nonane-9-carboxamide1212109-40-4C16H16BrNO3
- N-(4-Bromo-3,5-dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005053-14-4C17H18BrNO3
- N-(4-Bromo-2-chlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005275-25-1C15H13BrClNO3
- N-(3,4-Dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005288-37-8C17H19NO3
- N-(2,5-Dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1212278-02-8C17H19NO3
- 2-Oxo-N-(m-tolyl)hexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005288-39-0C16H17NO3
- N-(3,5-Dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005288-42-5C17H19NO3
- N-[4-(Acetylamino)phenyl]-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005288-63-0C17H18N2O4
- N-(4-Bromo-3-chloro-2-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1212416-64-2C16H15BrClNO3
- N-(4-Bromo-3-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005130-47-1C16H16BrNO3
- 6-Bromo-N-(4-ethoxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005238-17-4C17H18BrNO4
- 6-Bromo-N-(3-chloro-4-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005157-49-2C16H15BrClNO3
- 6-Bromo-N-(2,4-dichlorophenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005157-52-7C15H12BrCl2NO3
- 6-Bromo-2-oxo-N-phenylhexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005157-61-8C15H14BrNO3
- 6-Bromo-N-(3-chloro-2-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005238-29-8C16H15BrClNO3
- 6-Bromo-N-(5-chloro-2-methylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005157-75-4C16H15BrClNO3
- 6-Bromo-N-(3,4-dimethylphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1005157-88-9C17H18BrNO3
- Ethyl 4-{[(2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-yl)carbonyl]amino}benzoate1134426-45-1C18H19NO5
- N-(3-Hydroxyphenyl)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxamide1008668-99-2C15H15NO4