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Murcko scaffold

Ring system with 3 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
7
With full pages
3
Scaffold SMILES

O=C1CCSC(=Nc2ccccc2)N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCSC(=Nc2ccccc2)N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3-Benzyl-2-(4-fluorophenyl)imino-4-oxo-1,3-thiazinane-6-carboxylic acid chemical structure, C18H15FN2O3S, CAS 5932-52-5
3-Benzyl-2-(4-fluorophenyl)imino-4-oxo-1,3-thiazinane-6-carboxylic acid
CAS 5932-52-5C18H15FN2O3S
3-(3,4-Dimethoxybenzyl)-2-[(4-methoxyphenyl)imino]-4-oxo-1,3-thiazinane-6-carboxylic acid chemical structure, C21H22N2O6S, CAS 1164546-43-3
3-(3,4-Dimethoxybenzyl)-2-[(4-methoxyphenyl)imino]-4-oxo-1,3-thiazinane-6-carboxylic acid
CAS 1164546-43-3C21H22N2O6S
(Z)-3-(3,4-Dimethoxybenzyl)-2-((4-methoxyphenyl)imino)-N-methyl-4-oxo-1,3-thiazinane-6-carboxamide chemical structure, C22H25N3O5S, CAS 1146620-90-7
(Z)-3-(3,4-Dimethoxybenzyl)-2-((4-methoxyphenyl)imino)-N-methyl-4-oxo-1,3-thiazinane-6-carboxamide
CAS 1146620-90-7C22H25N3O5S
(Z)-3-(4-Fluorobenzyl)-2-((4-methoxyphenyl)imino)-4-oxo-1,3-thiazinane-6-carboxylic acid chemical structure, C19H17FN2O4S, CAS 522637-69-0
(Z)-3-(4-Fluorobenzyl)-2-((4-methoxyphenyl)imino)-4-oxo-1,3-thiazinane-6-carboxylic acid
CAS 522637-69-0C19H17FN2O4S
Tetrahydro-N-methyl-4-oxo-3-(phenylmethyl)-2-[[3-(trifluoromethyl)phenyl]imino]-2H-1,3-thiazine-6-carboxamide chemical structure, C20H18F3N3O2S, CAS 351354-48-8
Tetrahydro-N-methyl-4-oxo-3-(phenylmethyl)-2-[[3-(trifluoromethyl)phenyl]imino]-2H-1,3-thiazine-6-carboxamide
CAS 351354-48-8C20H18F3N3O2S
(2Z)-3-(4-Chlorobenzyl)-4-oxo-2-(phenylimino)-1,3-thiazinane-6-carboxylic acid chemical structure, C18H15ClN2O3S, CAS 312512-86-0
(2Z)-3-(4-Chlorobenzyl)-4-oxo-2-(phenylimino)-1,3-thiazinane-6-carboxylic acid
CAS 312512-86-0C18H15ClN2O3S
(2Z)-3-(4-Chlorobenzyl)-2-[(4-chlorophenyl)imino]-4-oxo-1,3-thiazinane-6-carboxamide chemical structure, C18H15Cl2N3O2S, CAS 470676-21-2
(2Z)-3-(4-Chlorobenzyl)-2-[(4-chlorophenyl)imino]-4-oxo-1,3-thiazinane-6-carboxamide
CAS 470676-21-2C18H15Cl2N3O2S