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Murcko scaffold

2,2-Diphenyl-1-(piperazin-1-yl)ethanone scaffold

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
22
With full pages
6
Scaffold SMILES

O=C(C(c1ccccc1)c1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,2-Diphenyl-1-(piperazin-1-yl)ethanone page
Murcko scaffold O=C(C(c1ccccc1)c1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

2-Hydroxy-1-(4-methylpiperazin-1-yl)-2,2-diphenylethanone chemical structure, C19H22N2O2, CAS 5067-93-6
2-Hydroxy-1-(4-methylpiperazin-1-yl)-2,2-diphenylethanone
CAS 5067-93-6C19H22N2O2
2-Methoxy-1-(4-methylpiperazin-1-yl)-2,2-diphenyl-ethanone chemical structure, C20H24N2O2, CAS 19178-73-5
2-Methoxy-1-(4-methylpiperazin-1-yl)-2,2-diphenyl-ethanone
CAS 19178-73-5C20H24N2O2
1-(4-Methylpiperazin-1-yl)-2,2-diphenylethanone chemical structure, C19H22N2O, CAS 56230-67-2
1-(4-Methylpiperazin-1-yl)-2,2-diphenylethanone
CAS 56230-67-2C19H22N2O
1-(4-Methylpiperazin-1-yl)-2,2-diphenylpropan-1-one chemical structure, C20H24N2O, CAS 94679-28-4
1-(4-Methylpiperazin-1-yl)-2,2-diphenylpropan-1-one
CAS 94679-28-4C20H24N2O
2,2-Diphenyl-1-(piperazin-1-yl)ethanone chemical structure, C18H20N2O, CAS 67199-13-7
2,2-Diphenyl-1-(piperazin-1-yl)ethanone
CAS 67199-13-7C18H20N2O
1-(4-Methylsulfonylpiperazin-1-yl)-2,2-diphenylethanone chemical structure, C19H22N2O3S, CAS 461413-52-5
1-(4-Methylsulfonylpiperazin-1-yl)-2,2-diphenylethanone
CAS 461413-52-5C19H22N2O3S
1-(4-Ethylsulfonylpiperazin-1-yl)-2,2-diphenylethanone chemical structure, C20H24N2O3S, CAS 428835-07-8
1-(4-Ethylsulfonylpiperazin-1-yl)-2,2-diphenylethanone
CAS 428835-07-8C20H24N2O3S
2,2-Diphenyl-1-(4-propylsulfonylpiperazin-1-yl)ethanone chemical structure, C21H26N2O3S, CAS 462602-43-3
2,2-Diphenyl-1-(4-propylsulfonylpiperazin-1-yl)ethanone
CAS 462602-43-3C21H26N2O3S
1-sec-Butyl-4-(diphenylacetyl)piperazine chemical structure, C22H28N2O, CAS 423740-92-5
1-sec-Butyl-4-(diphenylacetyl)piperazine
CAS 423740-92-5C22H28N2O
1-Piperazinecarboxylic acid, 4-(diphenylacetyl)-, ethyl ester chemical structure, C21H24N2O3, CAS 690673-54-2
1-Piperazinecarboxylic acid, 4-(diphenylacetyl)-, ethyl ester
CAS 690673-54-2C21H24N2O3
4-(Diphenylacetyl)-1-ethyl-1-methylpiperazin-1-ium iodide chemical structure, C21H27IN2O, CAS 100027-33-6
4-(Diphenylacetyl)-1-ethyl-1-methylpiperazin-1-ium iodide
CAS 100027-33-6C21H27IN2O
4-(Diphenylacetyl)piperazine-1-carbaldehyde chemical structure, C19H20N2O2, CAS 67199-20-6
4-(Diphenylacetyl)piperazine-1-carbaldehyde
CAS 67199-20-6C19H20N2O2
4-(Diphenylacetyl)piperazin-1-ium chemical structure, C18H21N2O+
4-(Diphenylacetyl)piperazin-1-ium
C18H21N2O+
Piperazine, 1-(diphenylacetyl)-4-propyl- chemical structure, C21H26N2O, CAS 798564-32-6
Piperazine, 1-(diphenylacetyl)-4-propyl-
CAS 798564-32-6C21H26N2O
Piperazine, 1-(diphenylacetyl)-4-(1-methyl-2-propenyl)- chemical structure, C22H26N2O, CAS 798564-34-8
Piperazine, 1-(diphenylacetyl)-4-(1-methyl-2-propenyl)-
CAS 798564-34-8C22H26N2O
2-Oxo-1,1-diphenyl-2-piperazin-1-ylethanol chemical structure, C18H20N2O2, CAS 857189-24-3
2-Oxo-1,1-diphenyl-2-piperazin-1-ylethanol
CAS 857189-24-3C18H20N2O2
2,2-Diphenyl-1-(piperazin-1-yl)ethanone 2,2,2-trifluoroacetate chemical structure, C20H21F3N2O3, CAS 435345-44-1
2,2-Diphenyl-1-(piperazin-1-yl)ethanone 2,2,2-trifluoroacetate
CAS 435345-44-1C20H21F3N2O3
2,2-Diphenyl-1-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethan-1-one chemical structure, C20H21F3N2O, CAS 1234945-77-7
2,2-Diphenyl-1-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethan-1-one
CAS 1234945-77-7C20H21F3N2O
1-[4-(But-2-en-1-yl)piperazin-1-yl]-2,2-diphenylethan-1-one chemical structure, C22H26N2O, CAS 798564-37-1
1-[4-(But-2-en-1-yl)piperazin-1-yl]-2,2-diphenylethan-1-one
CAS 798564-37-1C22H26N2O
1-[4-(4-Hydroxybut-2-yn-1-yl)piperazin-1-yl]-2,2-diphenylethan-1-one chemical structure, C22H24N2O2, CAS 798564-27-9
1-[4-(4-Hydroxybut-2-yn-1-yl)piperazin-1-yl]-2,2-diphenylethan-1-one
CAS 798564-27-9C22H24N2O2
2,2-Diphenyl-1-(piperazin-1-yl)ethan-1-one hydrochloride chemical structure, C18H21ClN2O, CAS 1839410-31-9
2,2-Diphenyl-1-(piperazin-1-yl)ethan-1-one hydrochloride
CAS 1839410-31-9C18H21ClN2O
1-(4-Ethyl-1-piperazinyl)-2-hydroxy-2,2-diphenylethanone hydrochloride chemical structure, C20H25ClN2O2, CAS 5048-91-9
1-(4-Ethyl-1-piperazinyl)-2-hydroxy-2,2-diphenylethanone hydrochloride
CAS 5048-91-9C20H25ClN2O2