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Murcko scaffold

Ring system with 4 rings and 25 atoms

34 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
34
With full pages
3
Scaffold SMILES

O=C(CCc1c[nH]c2ccccc12)NCCc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1c[nH]c2ccccc12)NCCc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

Tryptophyltryptophan chemical structure, C22H22N4O3, CAS 20696-60-0
Tryptophyltryptophan
CAS 20696-60-0C22H22N4O3
Boc-DL-Trp-DL-Trp-OMe chemical structure, C28H32N4O5, CAS 72254-56-9
Boc-DL-Trp-DL-Trp-OMe
CAS 72254-56-9C28H32N4O5
Boc-DL-Trp-DL-Trp-NHNH2 chemical structure, C27H32N6O4, CAS 72156-64-0
Boc-DL-Trp-DL-Trp-NHNH2
CAS 72156-64-0C27H32N6O4
Ethyl 2-[[2-amino-3-(5-fluoro-1H-indol-3-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoate chemical structure, C24H25FN4O3, CAS 1997-60-0
Ethyl 2-[[2-amino-3-(5-fluoro-1H-indol-3-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoate
CAS 1997-60-0C24H25FN4O3
(R)-2-((R)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-(1H-indol-3-yl)propanoic acid chemical structure, C22H22N4O3, CAS 58607-72-0
(R)-2-((R)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-(1H-indol-3-yl)propanoic acid
CAS 58607-72-0C22H22N4O3
EP-80661 chemical structure, C34H46N8O4, CAS 331941-57-2
EP-80661
CAS 331941-57-2C34H46N8O4
Macimorelin chemical structure, C26H30N6O3, CAS 381231-18-1
Macimorelin
CAS 381231-18-1C26H30N6O3
Antileukinate chemical structure, C45H66N18O7S, CAS 138559-60-1
Antileukinate
CAS 138559-60-1C45H66N18O7S
L-Valine, L-threonyl-L-valyl-L-glutaminyl-L-tryptophyl-L-tryptophyl- chemical structure, C41H55N9O9, CAS 528604-68-4
L-Valine, L-threonyl-L-valyl-L-glutaminyl-L-tryptophyl-L-tryptophyl-
CAS 528604-68-4C41H55N9O9
L-Alaninamide, N-acetyl-L-alanyl-L-tryptophyl-L-tryptophyl- chemical structure, C30H35N7O5, CAS 850833-14-6
L-Alaninamide, N-acetyl-L-alanyl-L-tryptophyl-L-tryptophyl-
CAS 850833-14-6C30H35N7O5
Glycyl-L-tryptophyl-L-tryptophan chemical structure, C24H25N5O4, CAS 57850-28-9
Glycyl-L-tryptophyl-L-tryptophan
CAS 57850-28-9C24H25N5O4
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-3-(1H-indol-3-yl)propanamide chemical structure, C21H20ClN3O, CAS 929809-38-1
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-3-(1H-indol-3-yl)propanamide
CAS 929809-38-1C21H20ClN3O
D-Tryptophanamide, 2-methylalanyl-N-[(1R)-1-(formylamino)-2-(2-methyl-1H-indol-3-yl)ethyl]-2-methyl- chemical structure, C28H34N6O3, CAS 381231-19-2
D-Tryptophanamide, 2-methylalanyl-N-[(1R)-1-(formylamino)-2-(2-methyl-1H-indol-3-yl)ethyl]-2-methyl-
CAS 381231-19-2C28H34N6O3
(S)-2-Acetamido-N-((S)-1-amino-3-(5-hydroxy-1H-indol-3-yl)-1-oxopropan-2-yl)-3-(5-hydroxy-1H-indol-3-yl)propanamide chemical structure, C24H25N5O5, CAS 71338-67-5
(S)-2-Acetamido-N-((S)-1-amino-3-(5-hydroxy-1H-indol-3-yl)-1-oxopropan-2-yl)-3-(5-hydroxy-1H-indol-3-yl)propanamide
CAS 71338-67-5C24H25N5O5
Trp-Trp-Thr chemical structure, C26H29N5O5, CAS 189455-44-5
Trp-Trp-Thr
CAS 189455-44-5C26H29N5O5
N-(tert-Butoxycarbonyl)-D-tryptophyl-D-tryptophan chemical structure, C27H30N4O5, CAS 160623-01-8
N-(tert-Butoxycarbonyl)-D-tryptophyl-D-tryptophan
CAS 160623-01-8C27H30N4O5
L-Tryptophyl-L-tryptophyl-L-methionyl-L-threonyl-L-glutaminyl-N~5~-(diaminomethylidene)-L-ornithine chemical structure, C42H58N12O9S, CAS 628302-30-7
L-Tryptophyl-L-tryptophyl-L-methionyl-L-threonyl-L-glutaminyl-N~5~-(diaminomethylidene)-L-ornithine
CAS 628302-30-7C42H58N12O9S
D-Tryptophyl-L-tryptophan chemical structure, C22H22N4O3, CAS 792960-11-3
D-Tryptophyl-L-tryptophan
CAS 792960-11-3C22H22N4O3
N-(3-Carboxypropanoyl)-L-tryptophyl-L-tryptophan chemical structure, C26H26N4O6, CAS 73205-75-1
N-(3-Carboxypropanoyl)-L-tryptophyl-L-tryptophan
CAS 73205-75-1C26H26N4O6
N-Acetyl-L-tryptophyl-L-tryptophyl-L-alaninamide chemical structure, C27H30N6O4, CAS 850833-06-6
N-Acetyl-L-tryptophyl-L-tryptophyl-L-alaninamide
CAS 850833-06-6C27H30N6O4
L-Cysteinyl-L-cysteinyl-L-tryptophyl-L-tryptophyl-L-cysteine chemical structure, C31H37N7O6S3, CAS 918412-82-5
L-Cysteinyl-L-cysteinyl-L-tryptophyl-L-tryptophyl-L-cysteine
CAS 918412-82-5C31H37N7O6S3
N-(tert-Butoxycarbonyl)-L-tryptophyl-L-tryptophan chemical structure, C27H30N4O5, CAS 90826-08-7
N-(tert-Butoxycarbonyl)-L-tryptophyl-L-tryptophan
CAS 90826-08-7C27H30N4O5
Ala-Trp-Trp chemical structure, C25H27N5O4, CAS 59005-79-7
Ala-Trp-Trp
CAS 59005-79-7C25H27N5O4
Trp-Trp-Ala chemical structure, C25H27N5O4, CAS 59005-78-6
Trp-Trp-Ala
CAS 59005-78-6C25H27N5O4