Murcko scaffold
Ring system with 6 rings and 32 atoms
42 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 32
- Chemicals
- 42
- With full pages
- 4
Scaffold SMILES
O=C1C(=c2sc3nc(-c4ccccc4)nn3c2=O)c2ccccc2N1Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 42 of 42 chemicals
![(3Z)-1-(4-Fluorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H14F2N4O2S, CAS 573941-10-3](/s/IVCIKMCESIUOKC-MRCUWXFGSA-N.svg)
(3Z)-1-(4-Fluorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 573941-10-3C25H14F2N4O2S
![(3Z)-1-(4-Chlorobenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H17ClN4O2S, CAS 573949-15-2](/s/FZGBPGVCTPCLSL-DQRAZIAOSA-N.svg)
(3Z)-1-(4-Chlorobenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 573949-15-2C26H17ClN4O2S
![(3Z)-3-(2-(4-Butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-B][1,2,4]triazol-5(6H)-ylidene)-1-(2-fluorobenzyl)-1,3-dihydro-2H-indol-2-one chemical structure, C29H23FN4O3S, CAS 606963-62-6](/s/MSSWRFSHHQHWSZ-IZHYLOQSSA-N.svg)
(3Z)-3-(2-(4-Butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-B][1,2,4]triazol-5(6H)-ylidene)-1-(2-fluorobenzyl)-1,3-dihydro-2H-indol-2-one
CAS 606963-62-6C29H23FN4O3S
![(3Z)-3-[2-(4-Butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-chlorobenzyl)-1,3-dihydro-2H-indol-2-one chemical structure, C29H23ClN4O3S, CAS 606963-65-9](/s/DTRQYMPMRLAWGB-IZHYLOQSSA-N.svg)
(3Z)-3-[2-(4-Butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-chlorobenzyl)-1,3-dihydro-2H-indol-2-one
CAS 606963-65-9C29H23ClN4O3S
![(3Z)-1-(4-Chlorobenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C28H21ClN4O3S, CAS 606963-17-1](/s/ZNBXAKYKTDDHDU-VHXPQNKSSA-N.svg)
(3Z)-1-(4-Chlorobenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 606963-17-1C28H21ClN4O3S
(3Z)-1-Benzyl-3-(6-oxo-2-(4-propoxyphenyl)(1,3)thiazolo(3,2-B)(1,2,4)triazol-5(6H)-ylidene)-1,3-dihydro-2H-indol-2-one
CAS 606963-07-9C28H22N4O3S
![(3Z)-1-Benzyl-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H18N4O2S, CAS 618854-51-6](/s/NUPLXICSYKGBBT-DQRAZIAOSA-N.svg)
(3Z)-1-Benzyl-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 618854-51-6C26H18N4O2S
![(3Z)-3-[2-(2-Methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-methylbenzyl)-1,3-dihydro-2H-indol-2-one chemical structure, C27H20N4O3S, CAS 618854-64-1](/s/JTRRNWWBGSWMKZ-FCQUAONHSA-N.svg)
(3Z)-3-[2-(2-Methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-methylbenzyl)-1,3-dihydro-2H-indol-2-one
CAS 618854-64-1C27H20N4O3S
![(3Z)-1-(4-Chlorobenzyl)-3-[2-(3-chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H14Cl2N4O2S, CAS 840515-50-6](/s/NHCFMXKUFSZKLY-MRCUWXFGSA-N.svg)
(3Z)-1-(4-Chlorobenzyl)-3-[2-(3-chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 840515-50-6C25H14Cl2N4O2S
![(3Z)-3-[2-(3-Chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-methylbenzyl)-1,3-dihydro-2H-indol-2-one chemical structure, C26H17ClN4O2S, CAS 618854-61-8](/s/QIMSTXWLRUTZSH-DQRAZIAOSA-N.svg)
(3Z)-3-[2-(3-Chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-methylbenzyl)-1,3-dihydro-2H-indol-2-one
CAS 618854-61-8C26H17ClN4O2S
![(3Z)-1-Benzyl-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H18N4O3S, CAS 618854-52-7](/s/AWQJGWGLDSYGGI-DQRAZIAOSA-N.svg)
(3Z)-1-Benzyl-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 618854-52-7C26H18N4O3S
![(3Z)-1-Benzyl-3-[2-(3-chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H15ClN4O2S, CAS 618854-48-1](/s/HESHESRGONXXAH-MRCUWXFGSA-N.svg)
(3Z)-1-Benzyl-3-[2-(3-chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 618854-48-1C25H15ClN4O2S
![(3Z)-1-(2-Chlorobenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C28H21ClN4O3S, CAS 573974-01-3](/s/SSBJIZZAEVKEBY-VHXPQNKSSA-N.svg)
(3Z)-1-(2-Chlorobenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 573974-01-3C28H21ClN4O3S
![(3Z)-1-(2-Fluorobenzyl)-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H17FN4O3S, CAS 578002-63-8](/s/TWKGQDTZBAWFIB-DQRAZIAOSA-N.svg)
(3Z)-1-(2-Fluorobenzyl)-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 578002-63-8C26H17FN4O3S
![(3Z)-1-(2-Chlorobenzyl)-3-[2-(3-chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H14Cl2N4O2S, CAS 578003-92-6](/s/MYBBUHQIHGZJKZ-MRCUWXFGSA-N.svg)
(3Z)-1-(2-Chlorobenzyl)-3-[2-(3-chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 578003-92-6C25H14Cl2N4O2S
![(3Z)-1-(4-Fluorobenzyl)-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H17FN4O3S, CAS 578757-60-5](/s/WJHQELJQULYJQK-DQRAZIAOSA-N.svg)
(3Z)-1-(4-Fluorobenzyl)-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 578757-60-5C26H17FN4O3S
![(3Z)-1-(2-Chlorobenzyl)-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H17ClN4O3S, CAS 618854-59-4](/s/OUJMDQSPXJEZAD-DQRAZIAOSA-N.svg)
(3Z)-1-(2-Chlorobenzyl)-3-[2-(2-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 618854-59-4C26H17ClN4O3S
![(3Z)-1-(2-Chlorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H14ClFN4O2S, CAS 618854-60-7](/s/JBHIYQMBNUZOMU-MRCUWXFGSA-N.svg)
(3Z)-1-(2-Chlorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 618854-60-7C25H14ClFN4O2S
![(3Z)-1-(4-Methylbenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C29H24N4O3S, CAS 578757-71-8](/s/UFFIHYVVHJZVHP-IZHYLOQSSA-N.svg)
(3Z)-1-(4-Methylbenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 578757-71-8C29H24N4O3S
![(3Z)-3-[2-(3-Chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(2-fluorobenzyl)-1,3-dihydro-2H-indol-2-one chemical structure, C25H14ClFN4O2S, CAS 578759-20-3](/s/KBVTYZGLPPLDFZ-MRCUWXFGSA-N.svg)
(3Z)-3-[2-(3-Chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(2-fluorobenzyl)-1,3-dihydro-2H-indol-2-one
CAS 578759-20-3C25H14ClFN4O2S
![(3Z)-1-(4-Chlorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H14ClFN4O2S, CAS 618854-69-6](/s/DVXAHPDLBKWBRH-MRCUWXFGSA-N.svg)
(3Z)-1-(4-Chlorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 618854-69-6C25H14ClFN4O2S
![(3Z)-1-(2-Chlorobenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C26H17ClN4O2S, CAS 578720-48-6](/s/HUPRQGUPEKHIJO-DQRAZIAOSA-N.svg)
(3Z)-1-(2-Chlorobenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 578720-48-6C26H17ClN4O2S
![(3Z)-1-Benzyl-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C25H15FN4O2S, CAS 585563-91-3](/s/UUIHQZGRBVYPJP-MRCUWXFGSA-N.svg)
(3Z)-1-Benzyl-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one
CAS 585563-91-3C25H15FN4O2S
![(3Z)-3-[2-(3-Chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-fluorobenzyl)-1,3-dihydro-2H-indol-2-one chemical structure, C25H14ClFN4O2S, CAS 586999-30-6](/s/SEAWJSPFACVHNQ-MRCUWXFGSA-N.svg)
(3Z)-3-[2-(3-Chlorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-fluorobenzyl)-1,3-dihydro-2H-indol-2-one
CAS 586999-30-6C25H14ClFN4O2S
- (3Z)-3-[2-(4-Butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(2-chlorobenzyl)-1,3-dihydro-2H-indol-2-one606963-63-7C29H23ClN4O3S
- (3Z)-1-(2-Fluorobenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one606963-13-7C28H21FN4O3S
- (3Z)-1-Benzyl-3-[2-(3,4-dimethoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one618854-49-2C27H20N4O4S
- (3Z)-1-(4-Methylbenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one618854-63-0C27H20N4O2S
- (3Z)-1-(2-Fluorobenzyl)-3-[2-(4-fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one618854-56-1C25H14F2N4O2S
- (3Z)-1-Benzyl-3-[2-(4-butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one606963-59-1C29H24N4O3S
- (3Z)-3-[2-(4-Butoxyphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-fluorobenzyl)-1,3-dihydro-2H-indol-2-one606963-66-0C29H23FN4O3S
- (3Z)-3-[2-(4-Fluorophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-(4-methylbenzyl)-1,3-dihydro-2H-indol-2-one573698-09-6C26H17FN4O2S
- (3Z)-1-Benzyl-3-[2-(2-bromophenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one618854-50-5C25H15BrN4O2S
- (3Z)-3-(2-(4-Ethoxyphenyl)-6-oxo[1,3]thiazolo[3,2-B][1,2,4]triazol-5(6H)-ylidene)-1-(2-fluorobenzyl)-1,3-dihydro-2H-indol-2-one606962-48-5C27H19FN4O3S
- 3-[2-(3,4-Dimethoxyphenyl)-6-oxothiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1-[(4-fluorophenyl)methyl]-1,3-dihydro-2H-indol-2-one577986-36-8C27H19FN4O4S
- 1-[(4-Chlorophenyl)methyl]-3-{6-oxo-2-[4-(pentyloxy)phenyl][1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene}-1,3-dihydro-2H-indol-2-one7066-75-3C30H25ClN4O3S
- 1-Benzyl-3-{2-[4-(hexyloxy)phenyl]-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene}-1,3-dihydro-2H-indol-2-one7066-76-4C31H28N4O3S
- (3Z)-1-(2-Fluorobenzyl)-3-(2-(4-methoxyphenyl)-6-oxo[1,3]thiazolo[3,2-B][1,2,4]triazol-5(6H)-ylidene)-1,3-dihydro-2H-indol-2-one606961-53-9C26H17FN4O3S
- (3Z)-1-Benzyl-3-(2-(4-ethoxyphenyl)-6-oxo[1,3]thiazolo[3,2-B][1,2,4]triazol-5(6H)-ylidene)-1,3-dihydro-2H-indol-2-one606962-44-1C27H20N4O3S
- (3Z)-1-(4-Fluorobenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one577764-52-4C26H17FN4O2S
- (3Z)-1-(2-Fluorobenzyl)-3-[2-(3-methylphenyl)-6-oxo[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one577763-32-7C26H17FN4O2S
- (3Z)-1-(4-Fluorobenzyl)-3-[6-oxo-2-(4-propoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-5(6H)-ylidene]-1,3-dihydro-2H-indol-2-one606963-19-3C28H21FN4O3S