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Murcko scaffold

Ring system with 4 rings and 21 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
9
With full pages
4
Scaffold SMILES

O=C1c2ccccc2C(=O)N1CC1CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2ccccc2C(=O)N1CC1CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(1S, 2R)-2-[(1.3-Dihydro-1.3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenylcyclopropanecarboxamide chemical structure, C23H24N2O3, CAS 1237261-65-2
(1S, 2R)-2-[(1.3-Dihydro-1.3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenylcyclopropanecarboxamide
CAS 1237261-65-2C23H24N2O3
2-((1,3-Dioxoisoindol-2-yl)methyl)-1-phenylcyclopropane-1-carboxylic acid chemical structure, C19H15NO4, CAS 69160-56-1
2-((1,3-Dioxoisoindol-2-yl)methyl)-1-phenylcyclopropane-1-carboxylic acid
CAS 69160-56-1C19H15NO4
2-((1,3-Dioxoisoindol-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide chemical structure, C23H24N2O3, CAS 1100753-09-0
2-((1,3-Dioxoisoindol-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide
CAS 1100753-09-0C23H24N2O3
rel-(1R,2S)-2-((1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide chemical structure, C23H24N2O3, CAS 105310-75-6
rel-(1R,2S)-2-((1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide
CAS 105310-75-6C23H24N2O3
Cyclopropanecarboxamide, 1-(2-chlorophenyl)-2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-, cis- chemical structure, C23H23ClN2O3, CAS 105310-76-7
Cyclopropanecarboxamide, 1-(2-chlorophenyl)-2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-, cis-
CAS 105310-76-7C23H23ClN2O3
cis-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)Methyl]-N-ethyl-1-phenyl chemical structure, C21H20N2O3, CAS 2386090-46-4
cis-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)Methyl]-N-ethyl-1-phenyl
CAS 2386090-46-4C21H20N2O3
rac-N-Desethyl-N-phthalimido Milnacipran chemical structure, C21H20N2O3
rac-N-Desethyl-N-phthalimido Milnacipran
C21H20N2O3
(1S,2R)-2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-N-ethyl-1-phenylcyclopropane-1-carboxamide chemical structure, C21H20N2O3, CAS 105310-73-4
(1S,2R)-2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-N-ethyl-1-phenylcyclopropane-1-carboxamide
CAS 105310-73-4C21H20N2O3
(1R,2S)-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenylcyclopropanecarboxamide-d10 chemical structure, C23H24N2O3, CAS 1246818-55-2
(1R,2S)-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenylcyclopropanecarboxamide-d10
CAS 1246818-55-2C23H24N2O3