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Murcko scaffold

2-Phenyl-4-(1-pyrrolidinyl)quinazoline scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
9
With full pages
4
Scaffold SMILES

c1ccc(-c2nc(N3CCCC3)c3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-4-(1-pyrrolidinyl)quinazoline page
Murcko scaffold c1ccc(-c2nc(N3CCCC3)c3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-(4-Nitrophenyl)-4-(pyrrolidin-1-yl)quinazoline chemical structure, C18H16N4O2, CAS 432518-68-8
2-(4-Nitrophenyl)-4-(pyrrolidin-1-yl)quinazoline
CAS 432518-68-8C18H16N4O2
2-(4-Chlorophenyl)-4-(pyrrolidin-1-yl)quinazoline chemical structure, C18H16ClN3, CAS 308300-07-4
2-(4-Chlorophenyl)-4-(pyrrolidin-1-yl)quinazoline
CAS 308300-07-4C18H16ClN3
2-Phenyl-4-(1-pyrrolidinyl)quinazoline chemical structure, C18H17N3, CAS 442536-98-3
2-Phenyl-4-(1-pyrrolidinyl)quinazoline
CAS 442536-98-3C18H17N3
2-(2-Fluorophenyl)-4-pyrrolidin-1-ylquinazoline chemical structure, C18H16FN3, CAS 422561-25-9
2-(2-Fluorophenyl)-4-pyrrolidin-1-ylquinazoline
CAS 422561-25-9C18H16FN3
2-[4-(1-Pyrrolidinyl)-2-quinazolinyl]phenol chemical structure, C18H17N3O, CAS 330982-05-3
2-[4-(1-Pyrrolidinyl)-2-quinazolinyl]phenol
CAS 330982-05-3C18H17N3O
2-(3-Nitrophenyl)-4-pyrrolidin-1-ylquinazoline chemical structure, C18H16N4O2, CAS 370845-53-7
2-(3-Nitrophenyl)-4-pyrrolidin-1-ylquinazoline
CAS 370845-53-7C18H16N4O2
2-(2-Chlorophenyl)-4-(pyrrolidin-1-yl)quinazoline chemical structure, C18H16ClN3, CAS 354992-07-7
2-(2-Chlorophenyl)-4-(pyrrolidin-1-yl)quinazoline
CAS 354992-07-7C18H16ClN3
2-(4-Bromophenyl)-4-pyrrolidin-1-ylquinazoline chemical structure, C18H16BrN3, CAS 305867-81-6
2-(4-Bromophenyl)-4-pyrrolidin-1-ylquinazoline
CAS 305867-81-6C18H16BrN3
2-(2-Fluorophenyl)-6-methoxy-4-(pyrrolidin-1-yl)quinazoline chemical structure, C19H18FN3O, CAS 757984-80-8
2-(2-Fluorophenyl)-6-methoxy-4-(pyrrolidin-1-yl)quinazoline
CAS 757984-80-8C19H18FN3O