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Murcko scaffold

1-(2-Benzylsulfanyl-4,5-dihydroimidazol-1-yl)-2-thiophen-2-ylethanone scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
13
With full pages
6
Scaffold SMILES

O=C(Cc1cccs1)N1CCN=C1SCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Benzylsulfanyl-4,5-dihydroimidazol-1-yl)-2-thiophen-2-ylethanone page
Murcko scaffold O=C(Cc1cccs1)N1CCN=C1SCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

1-(2-((2,5-Dimethylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone chemical structure, C18H20N2OS2, CAS 851804-65-4
1-(2-((2,5-Dimethylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone
CAS 851804-65-4C18H20N2OS2
1-[2-[(2-Chlorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone chemical structure, C16H15ClN2OS2, CAS 851804-13-2
1-[2-[(2-Chlorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone
CAS 851804-13-2C16H15ClN2OS2
1-(2-((2-Methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone chemical structure, C17H18N2OS2, CAS 851801-38-2
1-(2-((2-Methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone
CAS 851801-38-2C17H18N2OS2
1-(2-((4-Bromobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone chemical structure, C16H15BrN2OS2, CAS 851800-81-2
1-(2-((4-Bromobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone
CAS 851800-81-2C16H15BrN2OS2
1-[2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone chemical structure, C16H14ClFN2OS2, CAS 851803-00-4
1-[2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone
CAS 851803-00-4C16H14ClFN2OS2
2-(Thiophen-2-yl)-1-(2-((4-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)ethanone chemical structure, C17H15F3N2OS2, CAS 851806-45-6
2-(Thiophen-2-yl)-1-(2-((4-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)ethanone
CAS 851806-45-6C17H15F3N2OS2
1-[2-[(4-Nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone chemical structure, C16H15N3O3S2, CAS 851802-53-4
1-[2-[(4-Nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone
CAS 851802-53-4C16H15N3O3S2
1-[2-[(4-Methylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone chemical structure, C17H18N2OS2, CAS 851805-30-6
1-[2-[(4-Methylphenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone
CAS 851805-30-6C17H18N2OS2
1-(2-Benzylsulfanyl-4,5-dihydroimidazol-1-yl)-2-thiophen-2-ylethanone chemical structure, C16H16N2OS2, CAS 851864-48-7
1-(2-Benzylsulfanyl-4,5-dihydroimidazol-1-yl)-2-thiophen-2-ylethanone
CAS 851864-48-7C16H16N2OS2
1-[2-[(4-Fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone chemical structure, C16H15FN2OS2, CAS 851800-22-1
1-[2-[(4-Fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone
CAS 851800-22-1C16H15FN2OS2
1-(2-((2-Fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone chemical structure, C16H15FN2OS2, CAS 851807-18-6
1-(2-((2-Fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethanone
CAS 851807-18-6C16H15FN2OS2
1-[2-[(3-Fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone chemical structure, C16H15FN2OS2, CAS 851865-36-6
1-[2-[(3-Fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-2-thiophen-2-ylethanone
CAS 851865-36-6C16H15FN2OS2
1-(2-{[(2,4-Dichlorophenyl)methyl]sulfanyl}-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethan-1-one chemical structure, C16H14Cl2N2OS2, CAS 6255-88-5
1-(2-{[(2,4-Dichlorophenyl)methyl]sulfanyl}-4,5-dihydro-1H-imidazol-1-yl)-2-(thiophen-2-yl)ethan-1-one
CAS 6255-88-5C16H14Cl2N2OS2