Murcko scaffold
Ring system with 7 rings and 45 atoms
9 chemicals on CompoundList share this ring system.
- Rings
- 7
- Scaffold atoms
- 45
- Chemicals
- 9
- With full pages
- 0
Scaffold SMILES
O=C1OC2CC(CC=CC(OC3CCC(OC4CCCCO4)CO3)CC=CC=C3COC4CCC=C1C34)OC1(CCCCO1)C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 9 of 9 chemicals
2,3-Dehydro-3,4-dihydro ivermectin
CAS 1135339-49-9C48H74O14
delta-2-Ivermectin B1a
C48H74O14
Ivermectin impurity I
C48H74O14
rac-2,3-Dehydro-3,4-dihydro Ivermectin
C48H74O14
(4S)-2,3-Didehydro-5-O-demethyl-3,4,22,23-tetrahydroavermectin A1a
C48H74O14
Orb1984881
C48H74O14
Ivermectin EP impurity I
C48H74O14
![(4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,16Z,20R,21R,24R)-6'-[(2S)-Butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-1(23),10,14,16-tetraene-6,2'-oxane]-2-one chemical structure, C48H74O14](/s/AZSRBVAPBFWEGT-WAGPFJJZSA-N.svg)
(4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,16Z,20R,21R,24R)-6'-[(2S)-Butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-1(23),10,14,16-tetraene-6,2'-oxane]-2-one
C48H74O14
Delta2-ivermectin B1a
C48H74O14
Related scaffolds
Same ring framework with different atoms or bond orders
