Murcko scaffold
Ring system with 5 rings and 18 atoms
19 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 18
- Chemicals
- 19
- With full pages
- 6
Scaffold SMILES
O=C(Nc1ccccc1)C1CC2C=CC1C1CC21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 19 of 19 chemicals
![7-[(3-Chloro-2-methylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C18H18ClNO3, CAS 498531-12-7](/s/FXRGNCCXRZSTAZ-UHFFFAOYSA-N.svg)
7-[(3-Chloro-2-methylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 498531-12-7C18H18ClNO3
![7-[(4-Fluorophenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C17H16FNO3, CAS 469888-33-3](/s/FUUAOXCZTSOACV-UHFFFAOYSA-N.svg)
7-[(4-Fluorophenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 469888-33-3C17H16FNO3
![7-[(3-Methoxyphenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C18H19NO4, CAS 470691-53-3](/s/BTBDDWHUYILONR-UHFFFAOYSA-N.svg)
7-[(3-Methoxyphenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 470691-53-3C18H19NO4
![7-(2-Toluidinocarbonyl)tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C18H19NO3, CAS 473443-36-6](/s/HQGWLWWXSRABAP-UHFFFAOYSA-N.svg)
7-(2-Toluidinocarbonyl)tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 473443-36-6C18H19NO3
![7-[(2-Chloroanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C17H16ClNO3, CAS 6071-91-6](/s/JJMYIEVLLAMGNF-UHFFFAOYSA-N.svg)
7-[(2-Chloroanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 6071-91-6C17H16ClNO3
![7-{[4-(Methoxycarbonyl)anilino]carbonyl}tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H19NO5, CAS 322416-62-6](/s/BGFZEEHBWZWHHY-UHFFFAOYSA-N.svg)
7-{[4-(Methoxycarbonyl)anilino]carbonyl}tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 322416-62-6C19H19NO5
![7-[(2,3-Dimethylphenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO3, CAS 6368-99-6](/s/VAKLKLKPGNNVLR-UHFFFAOYSA-N.svg)
7-[(2,3-Dimethylphenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 6368-99-6C19H21NO3
Cambridge id 6369021
CAS 473574-86-6C18H19NO4
![7-[(3-Chloroanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C17H16ClNO3, CAS 321997-33-5](/s/NHPQBTUVOXYENI-UHFFFAOYSA-N.svg)
7-[(3-Chloroanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 321997-33-5C17H16ClNO3
![7-[(3-Acetylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H19NO4, CAS 1005127-22-9](/s/BTEWSGMMIUOGIN-UHFFFAOYSA-N.svg)
7-[(3-Acetylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 1005127-22-9C19H19NO4
![7-[(4-Bromo-2-ethylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H20BrNO3, CAS 1005127-23-0](/s/KAIBOPVJDVZKPL-UHFFFAOYSA-N.svg)
7-[(4-Bromo-2-ethylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 1005127-23-0C19H20BrNO3
![7-[(2,6-Dimethylphenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO3, CAS 1005047-09-5](/s/SYDQUWUBPNHBMA-UHFFFAOYSA-N.svg)
7-[(2,6-Dimethylphenyl)carbamoyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 1005047-09-5C19H21NO3
![7-(Anilinocarbonyl)tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C17H17NO3, CAS 464155-70-2](/s/GOPZCQQHIKFWSH-UHFFFAOYSA-N.svg)
7-(Anilinocarbonyl)tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 464155-70-2C17H17NO3
![7-[(3,4-Dimethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO5, CAS 930781-92-3](/s/BWRBKEICFLLOKE-UHFFFAOYSA-N.svg)
7-[(3,4-Dimethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 930781-92-3C19H21NO5
![7-[(2,5-Dimethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO5, CAS 1005035-07-3](/s/LNHFFFMSUQGAKR-UHFFFAOYSA-N.svg)
7-[(2,5-Dimethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 1005035-07-3C19H21NO5
![7-[(4-Bromoanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C17H16BrNO3, CAS 322728-78-9](/s/OZHCUZJMRICGGY-UHFFFAOYSA-N.svg)
7-[(4-Bromoanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 322728-78-9C17H16BrNO3
![7-[(2-Ethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO4, CAS 930781-87-6](/s/XEYUSPFUMMEJHA-UHFFFAOYSA-N.svg)
7-[(2-Ethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 930781-87-6C19H21NO4
![7-[(2,4-Dimethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO5, CAS 1005090-32-3](/s/HEKUWRKKNSYRRZ-UHFFFAOYSA-N.svg)
7-[(2,4-Dimethoxyanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 1005090-32-3C19H21NO5
![7-[(4-Ethylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid chemical structure, C19H21NO3, CAS 930781-85-4](/s/CBDMMLUXXBUSJP-UHFFFAOYSA-N.svg)
7-[(4-Ethylanilino)carbonyl]tricyclo[3.2.2.0~2,4~]non-8-ene-6-carboxylic acid
CAS 930781-85-4C19H21NO3