Murcko scaffold
Ring system with 5 rings and 22 atoms
19 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 22
- Chemicals
- 19
- With full pages
- 1
Scaffold SMILES
c1ccc(-c2nc3c4c5c(sc4ncn3n2)CNCC5)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 19 of 19 chemicals
![2-(9-Methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenol chemical structure, C17H15N5OS, CAS 381709-57-5](/s/VUDUHDYNPYLZGP-UHFFFAOYSA-N.svg)
2-(9-Methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenol
CAS 381709-57-5C17H15N5OS
![2-(4-Methoxyphenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C21H23N5OS, CAS 333774-64-4](/s/AZPWUHDTXXVKEX-UHFFFAOYSA-N.svg)
2-(4-Methoxyphenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 333774-64-4C21H23N5OS
![2-(8,8,10,10-Tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenol chemical structure, C20H21N5OS, CAS 333774-68-8](/s/WEYLAOAQZSAASB-UHFFFAOYSA-N.svg)
2-(8,8,10,10-Tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenol
CAS 333774-68-8C20H21N5OS
![2-(3,4-Dimethoxyphenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C22H25N5O2S, CAS 306294-29-1](/s/ISYUZMBSRMYBTI-UHFFFAOYSA-N.svg)
2-(3,4-Dimethoxyphenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 306294-29-1C22H25N5O2S
![2-(4-Fluorophenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C20H20FN5S, CAS 510723-90-7](/s/CQZAVXQAWRKGEX-UHFFFAOYSA-N.svg)
2-(4-Fluorophenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 510723-90-7C20H20FN5S
![2-(2-Chlorophenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C20H20ClN5S, CAS 308106-95-8](/s/OURKWCFJWHTGFM-UHFFFAOYSA-N.svg)
2-(2-Chlorophenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 308106-95-8C20H20ClN5S
![8,8,10,10-Tetramethyl-2-(4-methylphenyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C21H23N5S, CAS 326871-28-7](/s/DXRXPRURXMIZTN-UHFFFAOYSA-N.svg)
8,8,10,10-Tetramethyl-2-(4-methylphenyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 326871-28-7C21H23N5S
![8,8,10,10-Tetramethyl-2-(2-methylphenyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C21H23N5S, CAS 333775-36-3](/s/ZJUGPXDVYYEFEN-UHFFFAOYSA-N.svg)
8,8,10,10-Tetramethyl-2-(2-methylphenyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 333775-36-3C21H23N5S
![2-(2-Methoxyphenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C21H23N5OS, CAS 380904-48-3](/s/GKVSDMTYFVVNIU-UHFFFAOYSA-N.svg)
2-(2-Methoxyphenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 380904-48-3C21H23N5OS
![N,N-Dimethyl-4-(8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)aniline chemical structure, C22H26N6S, CAS 573696-27-2](/s/KXKRYKMFEATLJE-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-(8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)aniline
CAS 573696-27-2C22H26N6S
![2-(4-Chlorophenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C20H20ClN5S, CAS 627053-85-4](/s/PZXSJEGNYXBCPW-UHFFFAOYSA-N.svg)
2-(4-Chlorophenyl)-8,8,10,10-tetramethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 627053-85-4C20H20ClN5S
![2-(4-Fluorophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C17H14FN5S, CAS 902019-77-6](/s/KOKVLYWTAZHZAW-UHFFFAOYSA-N.svg)
2-(4-Fluorophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 902019-77-6C17H14FN5S
![2-(2,4-Dichlorophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C17H13Cl2N5S, CAS 902023-22-7](/s/HHTFLSPRFXZGTH-UHFFFAOYSA-N.svg)
2-(2,4-Dichlorophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 902023-22-7C17H13Cl2N5S
![2-(3-Isopropoxyphenyl)-5,9-dimethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C21H23N5OS, CAS 904262-09-5](/s/JJNKVDOWZJAWCS-UHFFFAOYSA-N.svg)
2-(3-Isopropoxyphenyl)-5,9-dimethyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 904262-09-5C21H23N5OS
![9-Methyl-2-(3-propoxyphenyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C20H21N5OS, CAS 902312-33-8](/s/MBYUGKLLSRZXJQ-UHFFFAOYSA-N.svg)
9-Methyl-2-(3-propoxyphenyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 902312-33-8C20H21N5OS
![N,N-Dimethyl-4-(9-propyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)aniline chemical structure, C21H24N6S, CAS 879569-85-4](/s/SATHAKITLGIPAS-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-(9-propyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)aniline
CAS 879569-85-4C21H24N6S
![2-(2-Methoxyphenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C18H17N5OS, CAS 902334-64-9](/s/JZOQOOMMGLSPJE-UHFFFAOYSA-N.svg)
2-(2-Methoxyphenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 902334-64-9C18H17N5OS
![2-(2-Bromophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C17H14BrN5S, CAS 902324-12-3](/s/QCMAAAGSDOOERT-UHFFFAOYSA-N.svg)
2-(2-Bromophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 902324-12-3C17H14BrN5S
![2-(4-Chlorophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C17H14ClN5S, CAS 902316-12-5](/s/JZSHZSLURQUDEY-UHFFFAOYSA-N.svg)
2-(4-Chlorophenyl)-9-methyl-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
CAS 902316-12-5C17H14ClN5S
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc(-n2c[n+]3c(n2)COC2Cc4ccccc4C23)cc1](/scaffold/RPIXTYYRQOACOQ-UHFFFAOYSA-N/structure.svg)
