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Murcko scaffold

Ring system with 3 rings and 17 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
17
With full pages
5
Scaffold SMILES

O=c1cc(N2CCCCC2)nc2ccccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(N2CCCCC2)nc2ccccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

9-Methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C15H17N3O2, CAS 303792-40-7
9-Methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 303792-40-7C15H17N3O2
9-Methyl-2-(4-methylpiperidin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H19N3O2, CAS 300377-10-0
9-Methyl-2-(4-methylpiperidin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 300377-10-0C16H19N3O2
2-((9-Methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidin-3-yl)methylene)malononitrile chemical structure, C18H17N5O, CAS 391890-14-5
2-((9-Methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidin-3-yl)methylene)malononitrile
CAS 391890-14-5C18H17N5O
2-(4-Methylpiperidin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C15H17N3O2, CAS 331948-27-7
2-(4-Methylpiperidin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 331948-27-7C15H17N3O2
4-Oxo-2-piperidin-1-yl-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C14H15N3O2, CAS 33345-96-9
4-Oxo-2-piperidin-1-yl-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 33345-96-9C14H15N3O2
1-(3-Formyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxamide chemical structure, C15H16N4O3, CAS 636991-30-5
1-(3-Formyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxamide
CAS 636991-30-5C15H16N4O3
7-Methyl-4-oxo-2-piperidin-1-yl-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C15H17N3O2, CAS 300586-42-9
7-Methyl-4-oxo-2-piperidin-1-yl-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 300586-42-9C15H17N3O2
1-{3-Formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidine-4-carboxamide chemical structure, C16H18N4O3, CAS 889814-81-7
1-{3-Formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidine-4-carboxamide
CAS 889814-81-7C16H18N4O3
Ethyl 1-(3-formyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxylate chemical structure, C17H19N3O4, CAS 636991-29-2
Ethyl 1-(3-formyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxylate
CAS 636991-29-2C17H19N3O4
Ethyl 1-(3-formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxylate chemical structure, C18H21N3O4, CAS 636989-80-5
Ethyl 1-(3-formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxylate
CAS 636989-80-5C18H21N3O4
2-(3,5-Dimethylpiperidin-1-yl)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C17H21N3O2, CAS 610756-82-6
2-(3,5-Dimethylpiperidin-1-yl)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 610756-82-6C17H21N3O2
7-Methyl-2-(4-methylpiperidin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H19N3O2, CAS 433325-87-2
7-Methyl-2-(4-methylpiperidin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 433325-87-2C16H19N3O2
(E)-9-Methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde oxime chemical structure, C15H18N4O2, CAS 304865-07-4
(E)-9-Methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde oxime
CAS 304865-07-4C15H18N4O2
N-(1-{4-Oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-4-yl)methanesulfonamide chemical structure, C14H18N4O3S, CAS 950073-68-4
N-(1-{4-Oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-4-yl)methanesulfonamide
CAS 950073-68-4C14H18N4O3S
2-[3-(Fluoromethyl)piperidin-1-yl]-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C14H16FN3O, CAS 2640969-74-8
2-[3-(Fluoromethyl)piperidin-1-yl]-4H-pyrido[1,2-a]pyrimidin-4-one
CAS 2640969-74-8C14H16FN3O
2-[4-(Fluoromethyl)piperidin-1-yl]-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C14H16FN3O, CAS 2742026-88-4
2-[4-(Fluoromethyl)piperidin-1-yl]-4H-pyrido[1,2-a]pyrimidin-4-one
CAS 2742026-88-4C14H16FN3O
N-(1-{4-Oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl)methanesulfonamide chemical structure, C14H18N4O3S, CAS 2770586-49-5
N-(1-{4-Oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl)methanesulfonamide
CAS 2770586-49-5C14H18N4O3S