Murcko scaffold
2'-Phenyl-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] scaffold
23 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 23
- Chemicals
- 23
- With full pages
- 9
Scaffold SMILES
c1ccc(C2=NN3C(C2)c2ccccc2OC32CCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
![2'-Phenyl-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C20H20N2O, CAS 140473-07-0](/s/ZRJHDVIQVQKWQR-UHFFFAOYSA-N.svg)
2'-Phenyl-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 140473-07-0C20H20N2O
![9'-Bromo-2'-phenyl-1',10'b-dihydrospiro(cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine) chemical structure, C20H19BrN2O, CAS 332060-14-7](/s/GQQUGEMPWFVPRJ-UHFFFAOYSA-N.svg)
9'-Bromo-2'-phenyl-1',10'b-dihydrospiro(cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine)
CAS 332060-14-7C20H19BrN2O
![2'-(4-Chlorophenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C20H19ClN2O, CAS 313239-94-0](/s/VJQMUTGVAWNULL-UHFFFAOYSA-N.svg)
2'-(4-Chlorophenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 313239-94-0C20H19ClN2O
![2-Chloro-9-(4-chlorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C20H18Cl2N2O, CAS 332060-47-6](/s/JIYYHRHLIIVOHY-UHFFFAOYSA-N.svg)
2-Chloro-9-(4-chlorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 332060-47-6C20H18Cl2N2O
![2-Chloro-9-(4-methylphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C21H21ClN2O, CAS 332061-13-9](/s/XTAFYBZMBMMAKI-UHFFFAOYSA-N.svg)
2-Chloro-9-(4-methylphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 332061-13-9C21H21ClN2O
![9'-Bromo-2'-(4-methylphenyl)-1',10'b-dihydrospiro(cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine) chemical structure, C21H21BrN2O, CAS 332061-34-4](/s/QGGYNTCAGNGCGZ-UHFFFAOYSA-N.svg)
9'-Bromo-2'-(4-methylphenyl)-1',10'b-dihydrospiro(cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine)
CAS 332061-34-4C21H21BrN2O
![2'-(4-Methoxyphenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C21H22N2O2, CAS 302583-66-0](/s/BHWPOVDAKWUESY-UHFFFAOYSA-N.svg)
2'-(4-Methoxyphenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 302583-66-0C21H22N2O2
![9-Chloro-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane] chemical structure, C21H21ClN2O2, CAS 303061-30-5](/s/UUUKYIJBFLBCNO-UHFFFAOYSA-N.svg)
9-Chloro-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane]
CAS 303061-30-5C21H21ClN2O2
![9-Bromo-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane] chemical structure, C21H21BrN2O2, CAS 303060-88-0](/s/DSVYKWHOBBCSNO-UHFFFAOYSA-N.svg)
9-Bromo-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane]
CAS 303060-88-0C21H21BrN2O2
![4-Methoxy-9-(4-methoxyphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C22H24N2O3, CAS 849828-72-4](/s/QJTFFRBOVKXHDK-UHFFFAOYSA-N.svg)
4-Methoxy-9-(4-methoxyphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 849828-72-4C22H24N2O3
![9-Chloro-2-(3-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane] chemical structure, C21H21ClN2O2, CAS 877787-85-4](/s/CJSMZRKLOOXNPP-UHFFFAOYSA-N.svg)
9-Chloro-2-(3-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane]
CAS 877787-85-4C21H21ClN2O2
![9-(4-Fluorophenyl)-4-methoxyspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C21H21FN2O2, CAS 862489-07-4](/s/FBQPDGXUDLHWTA-UHFFFAOYSA-N.svg)
9-(4-Fluorophenyl)-4-methoxyspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 862489-07-4C21H21FN2O2
![2-Bromo-9-(4-fluorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6, 1'-cyclopentane] chemical structure, C20H18BrFN2O, CAS 850239-31-5](/s/RWVPDRATCYXWLK-UHFFFAOYSA-N.svg)
2-Bromo-9-(4-fluorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6, 1'-cyclopentane]
CAS 850239-31-5C20H18BrFN2O
![2-Bromo-9-(4-chlorophenyl)-4-methoxyspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C21H20BrClN2O2, CAS 877783-82-9](/s/XPRZKCCNDBMIRK-UHFFFAOYSA-N.svg)
2-Bromo-9-(4-chlorophenyl)-4-methoxyspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 877783-82-9C21H20BrClN2O2
![4-Methoxy-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclo pentane] chemical structure, C21H22N2O2, CAS 877799-92-3](/s/JMLHZBYCPQEOFH-UHFFFAOYSA-N.svg)
4-Methoxy-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclo pentane]
CAS 877799-92-3C21H22N2O2
![2'-(3-Methoxyphenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C21H22N2O2, CAS 877779-09-4](/s/LUTUIERBGPSTFI-UHFFFAOYSA-N.svg)
2'-(3-Methoxyphenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 877779-09-4C21H22N2O2
![2-Bromo-9-(4-chlorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6, 1'-cyclopentane] chemical structure, C20H18BrClN2O, CAS 332060-67-0](/s/JOGJKGYXJNOUMK-UHFFFAOYSA-N.svg)
2-Bromo-9-(4-chlorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6, 1'-cyclopentane]
CAS 332060-67-0C20H18BrClN2O
![4-Methoxy-9-(3-methoxyphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C22H24N2O3, CAS 877779-40-3](/s/WEHDEPAZVCRDBC-UHFFFAOYSA-N.svg)
4-Methoxy-9-(3-methoxyphenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 877779-40-3C22H24N2O3
![2'-(4-Chlorophenyl)-1',10'b-dihydro-7'-methoxyspiro[cyclopentane-1,5'-[5H]pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C21H21ClN2O2, CAS 877790-48-2](/s/GVCKZIWRJVVAHS-UHFFFAOYSA-N.svg)
2'-(4-Chlorophenyl)-1',10'b-dihydro-7'-methoxyspiro[cyclopentane-1,5'-[5H]pyrazolo[1,5-c][1,3]benzoxazine]
CAS 877790-48-2C21H21ClN2O2
![2-Chloro-9-(4-fluorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane] chemical structure, C20H18ClFN2O, CAS 849911-65-5](/s/FEMZAURGBRDXAR-UHFFFAOYSA-N.svg)
2-Chloro-9-(4-fluorophenyl)spiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclopentane]
CAS 849911-65-5C20H18ClFN2O
![7',9'-Dibromo-2'-(4-methoxyphenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine] chemical structure, C21H20Br2N2O2, CAS 850245-15-7](/s/UXPMNIDUSJASJT-UHFFFAOYSA-N.svg)
7',9'-Dibromo-2'-(4-methoxyphenyl)-1',10b'-dihydrospiro[cyclopentane-1,5'-pyrazolo[1,5-c][1,3]benzoxazine]
CAS 850245-15-7C21H20Br2N2O2
![2-Chloro-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclop entane] chemical structure, C20H19ClN2O, CAS 332059-91-3](/s/AVEINBRSSSIIRE-UHFFFAOYSA-N.svg)
2-Chloro-9-phenylspiro[10aH-benzo[e]2-pyrazolino[1,5-c]1,3-oxazine-6,1'-cyclop entane]
CAS 332059-91-3C20H19ClN2O
![7,9-Dichloro-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane] chemical structure, C21H20Cl2N2O2, CAS 303061-46-3](/s/OMDQRBNDJUGASS-UHFFFAOYSA-N.svg)
7,9-Dichloro-2-(4-methoxyphenyl)-1,10B-dihydrospiro[benzo[E]pyrazolo[1,5-C][1,3]oxazine-5,1'-cyclopentane]
CAS 303061-46-3C21H20Cl2N2O2