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Murcko scaffold

Ring system with 4 rings and 26 atoms

43 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
43
With full pages
1
Scaffold SMILES

O=C(Nc1nc2ccccc2s1)c1cccn(Cc2ccccc2)c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc2ccccc2s1)c1cccn(Cc2ccccc2)c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

1-Benzyl-N-(4-methyl-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H17N3O2S, CAS 946353-53-3
1-Benzyl-N-(4-methyl-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946353-53-3C21H17N3O2S
N-(6-Methyl-1,3-benzothiazol-2-yl)-1-[(4-methylphenyl)methyl]-2-oxopyridine-3-carboxamide chemical structure, C22H19N3O2S, CAS 946221-33-6
N-(6-Methyl-1,3-benzothiazol-2-yl)-1-[(4-methylphenyl)methyl]-2-oxopyridine-3-carboxamide
CAS 946221-33-6C22H19N3O2S
1-(3-Fluorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16FN3O2S, CAS 1005300-09-3
1-(3-Fluorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 1005300-09-3C21H16FN3O2S
1-(4-Fluorobenzyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16FN3O2S, CAS 946354-50-3
1-(4-Fluorobenzyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946354-50-3C21H16FN3O2S
N-(6-Ethoxybenzo[d]thiazol-2-yl)-1-(2-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C23H21N3O3S, CAS 946354-98-9
N-(6-Ethoxybenzo[d]thiazol-2-yl)-1-(2-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946354-98-9C23H21N3O3S
N-(Benzo[d]thiazol-2-yl)-1-(4-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H14ClN3O2S, CAS 899991-36-7
N-(Benzo[d]thiazol-2-yl)-1-(4-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 899991-36-7C20H14ClN3O2S
1-(4-Chlorobenzyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16ClN3O2S, CAS 946302-79-0
1-(4-Chlorobenzyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946302-79-0C21H16ClN3O2S
1-(4-Chlorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16ClN3O2S, CAS 941952-25-6
1-(4-Chlorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 941952-25-6C21H16ClN3O2S
N-(6-Methylbenzo[d]thiazol-2-yl)-1-(3-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C22H19N3O2S, CAS 946248-33-5
N-(6-Methylbenzo[d]thiazol-2-yl)-1-(3-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946248-33-5C22H19N3O2S
N-(4-Methylbenzo[d]thiazol-2-yl)-1-(3-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C22H19N3O2S, CAS 899947-99-0
N-(4-Methylbenzo[d]thiazol-2-yl)-1-(3-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 899947-99-0C22H19N3O2S
N-(Benzo[d]thiazol-2-yl)-1-(2-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H14ClN3O2S, CAS 899754-14-4
N-(Benzo[d]thiazol-2-yl)-1-(2-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 899754-14-4C20H14ClN3O2S
1-(2-Chlorobenzyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16ClN3O2S, CAS 946356-68-9
1-(2-Chlorobenzyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946356-68-9C21H16ClN3O2S
1-(2-Chlorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16ClN3O2S, CAS 1005298-62-3
1-(2-Chlorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 1005298-62-3C21H16ClN3O2S
N-(Benzo[d]thiazol-2-yl)-1-(2,5-dimethylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C22H19N3O2S, CAS 946377-95-3
N-(Benzo[d]thiazol-2-yl)-1-(2,5-dimethylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946377-95-3C22H19N3O2S
N-(4-Methylbenzo[d]thiazol-2-yl)-1-(4-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C22H19N3O2S, CAS 899991-59-4
N-(4-Methylbenzo[d]thiazol-2-yl)-1-(4-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 899991-59-4C22H19N3O2S
N-(Benzo[d]thiazol-2-yl)-1-(2-fluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H14FN3O2S, CAS 941910-26-5
N-(Benzo[d]thiazol-2-yl)-1-(2-fluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 941910-26-5C20H14FN3O2S
1-(2-Fluorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16FN3O2S, CAS 941904-05-8
1-(2-Fluorobenzyl)-N-(4-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 941904-05-8C21H16FN3O2S
N-(Benzo[d]thiazol-2-yl)-1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H14ClN3O2S, CAS 899991-88-9
N-(Benzo[d]thiazol-2-yl)-1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 899991-88-9C20H14ClN3O2S
N-(Benzo[d]thiazol-2-yl)-1-(3-nitrobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H14N4O4S, CAS 941953-34-0
N-(Benzo[d]thiazol-2-yl)-1-(3-nitrobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 941953-34-0C20H14N4O4S
1-(4-Chlorobenzyl)-N-(6-ethoxybenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C22H18ClN3O3S, CAS 946355-37-9
1-(4-Chlorobenzyl)-N-(6-ethoxybenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 946355-37-9C22H18ClN3O3S
1-[(3-Methylphenyl)methyl]-N-(6-nitro-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C21H16N4O4S, CAS 923073-84-1
1-[(3-Methylphenyl)methyl]-N-(6-nitro-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 923073-84-1C21H16N4O4S
1-[(2-Chlorophenyl)methyl]-N-(6-nitro-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H13ClN4O4S, CAS 941909-78-0
1-[(2-Chlorophenyl)methyl]-N-(6-nitro-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 941909-78-0C20H13ClN4O4S
1-(2,5-Dimethylbenzyl)-N-(6-nitrobenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C22H18N4O4S, CAS 941989-57-7
1-(2,5-Dimethylbenzyl)-N-(6-nitrobenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 941989-57-7C22H18N4O4S
1-(2-Fluorobenzyl)-N-(6-nitrobenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C20H13FN4O4S, CAS 942008-37-9
1-(2-Fluorobenzyl)-N-(6-nitrobenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 942008-37-9C20H13FN4O4S