Murcko scaffold
Ring system with 6 rings and 40 atoms
29 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 40
- Chemicals
- 29
- With full pages
- 5
Scaffold SMILES
O=C(NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 29 of 29 chemicals
N-((9H-Fluoren-9-ylmethoxy)carbonyl)-S-(triphenylmethyl)-L-cysteine
CAS 103213-32-7C37H31NO4S
Fmoc-DL-Cys(Trt)-OH
CAS 200947-68-8C37H31NO4S
Fmoc-D-Cys(Trt)-OH
CAS 167015-11-4C37H31NO4S
Fmoc-Cysteinol(Trt)
CAS 215954-72-6C37H33NO3S
Fmoc-S-4-methoxytrityl-L-cysteine
CAS 177582-21-7C38H33NO5S
Allyl N-Fmoc-S-trityl-L-cysteinate
CAS 640722-84-5C40H35NO4S
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-S-(triphenylmethyl)-L-cysteine chemical structure, C38H33NO4S, CAS 725728-43-8](/s/AWLPKAIRGNZKIN-QNGWXLTQSA-N.svg)
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-S-(triphenylmethyl)-L-cysteine
CAS 725728-43-8C38H33NO4S
Fmoc-alpha-Me-D-Cys(Trt)-OH
CAS 725728-37-0C38H33NO4S
(3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-tritylsulfanylbutanoic acid
CAS 2955636-48-1C38H33NO4S
(3R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((triphenylmethyl)sulfanyl)butanoic acid
CAS 646068-80-6C38H33NO4S
![Boc-L-Thr[Fmoc-L-Cys(Trt)]-OH chemical structure, C46H46N2O8S, CAS 944283-30-1](/s/FEWLVVHWXDASNF-BIPSGFNESA-N.svg)
Boc-L-Thr[Fmoc-L-Cys(Trt)]-OH
CAS 944283-30-1C46H46N2O8S
![Fmoc-N-[2-(tritylmercapto)ethyl]glycine chemical structure, C38H33NO4S, CAS 882847-27-0](/s/UJSOKTVPMWHIDT-UHFFFAOYSA-N.svg)
Fmoc-N-[2-(tritylmercapto)ethyl]glycine
CAS 882847-27-0C38H33NO4S
Fmoc-Pen(Trt)-OH
CAS 201531-88-6C39H35NO4S
Fmoc-D-Pen(Trt)-OH
CAS 201532-01-6C39H35NO4S
Fmoc-D-Cys(Mmt)-OH
CAS 1198791-73-9C38H33NO5S
Fmoc-N-Me-D-Cys(Trt)-OH
CAS 1349807-46-0C38H33NO4S
![9H-Fluoren-9-ylmethyl N-[(2R)-1-oxo-3-[(triphenyl-methyl)sulfanyl]propan-2-yl]carbamate chemical structure, C37H31NO3S, CAS 505076-77-7](/s/FEFWRXFCWGLFQX-SSEXGKCCSA-N.svg)
9H-Fluoren-9-ylmethyl N-[(2R)-1-oxo-3-[(triphenyl-methyl)sulfanyl]propan-2-yl]carbamate
CAS 505076-77-7C37H31NO3S
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-((4-methylphenyl)(diphenyl)methyl)-L-cysteine
CAS 269067-38-1C38H33NO4S
Fmoc-Cys(Trt)-NH2
CAS 202752-01-0C37H32N2O3S
Fmoc-Cys(Trt)-OMe
CAS 245088-56-6C38H33NO4S
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(tritylthio)propanoic acid
CAS 944797-51-7C38H33NO4S
![9H-Fluoren-9-ylmethyl N-[(1R)-1-[methoxy(methyl)carbamoyl]-2-[(triphenylmethyl)sulfanyl]ethyl]carbamate chemical structure, C39H36N2O4S, CAS 370857-83-3](/s/BPQRFVRQWPPXIQ-BHVANESWSA-N.svg)
9H-Fluoren-9-ylmethyl N-[(1R)-1-[methoxy(methyl)carbamoyl]-2-[(triphenylmethyl)sulfanyl]ethyl]carbamate
CAS 370857-83-3C39H36N2O4S
Fmoc-D-Cys(Mtt)-OH
CAS 252206-29-4C38H33NO4S
Fmoc-alpha-Me-L-Cys(Mmt)-OH
CAS 1198791-74-0C39H35NO5S
- 1 suppliersFmoc-MeCys(Mmt)-OH2907774-77-8C39H35NO5S
- (9H-Fluoren-9-yl)methyl (S)-(1-amino-1-oxo-3-(tritylthio)propan-2-yl)carbamate2197916-88-2C37H32N2O3S
- Fmoc-Cys(Trt)-OH-d2360565-11-3C37H31NO4S
- Fmoc-Cys(Trt)-OH-1,2,3-13C3,15N360795-94-4C37H31NO4S
- N-(((2,7-Disulfo-9H-fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-cysteine potassium salt (Smoc-L-Cys(Trt)-OH)2442552-68-1C37H31NO10S3
Related scaffolds
Same ring framework with different atoms or bond orders
