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2-Hexanone safety data

GHS hazards, precautions, first aid, handling and transport for 2-Hexanone. A classification summary, not a safety data sheet.
CAS 591-78-6Formula C6H12O

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

GHS classification

Pictograms, signal word and hazard classes of the GHS classification

GHS02: Flammable
Flammable
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
Signal word
Danger
320
NFPA 704 rating
health, fire, reactivity

Hazard classes and categories

  • Flam. Liq. 3
  • STOT SE 3 (narcotic effects)
  • Repr. 2
  • STOT RE 1

Hazard statements

H codes grouped by type. Percentages show the share of classification notifications that report the statement

Physical hazards

  • H226Flammable liquid and vapour.

Health hazards

  • H336May cause drowsiness or dizziness.
  • H361fSuspected of damaging fertility.
  • H372Causes damage to organs through prolonged or repeated exposure.

Precautionary statements

P codes for prevention, response, storage and disposal

Prevention

  • P203Obtain, read and follow all safety instructions before use.
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.

Response

  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P370 + P378In case of fire: Use appropriate media to extinguish.

Storage

  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.

Disposal

  • P501Dispose of contents and container in accordance with local regulations.

First aid

General first aid measures. Get medical advice if you feel unwell

If inhaled
IMMEDIATELY leave the contaminated area, take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used, if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
Skin contact
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
Eye contact
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
If swallowed
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

Handling, storage and disposal

Summaries only, follow the supplier SDS for your grade

Safe handling

Fire: NO open flames, NO sparks and NO smoking. Above 23 °C use a closed system, ventilation and explosion-proof electrical equipment.

Inhalation: Use ventilation, local exhaust or breathing protection.

Skin: Protective gloves. Protective clothing.

Eyes: Wear face shield or eye protection in combination with breathing protection.

Ingestion: Do not eat, drink, or smoke during work.

Storage

Fireproof. Separated from strong oxidants.

Disposal

2-Hexanone was shown to undergo rapid (less than eight weeks) anaerobic biodegradation utilizing an anaerobic digester sludge inoculum. The following wastewater treatment technologies have been investigated for 2-hexanone: Activated carbon.

Exposure limits and toxicity

Occupational exposure limits and toxicity data

OSHA PEL, 8-hour TWA
100 ppm (410 mg/m³)
NIOSH REL, TWA
1 ppm (4 mg/m³)
ACGIH TLV, 8-hour TWA
5 ppm
ACGIH TLV, STEL
10 ppm
IDLH
1600 ppm

Short-term exposure: The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the nervous system. Exposure far above the OEL could cause unconsciousness. Long-term exposure: Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the nervous system.

Transport information

UN dangerous goods classification for road, sea and air

UN number
UN 1224
Transport hazard class
3
Packing group
III

Shipping rules depend on mode, quantity and packaging. Confirm the classification with the supplier SDS and your freight forwarder.

Supplier safety data sheets

SDS documents uploaded by suppliers who list this chemical

No supplier has uploaded an SDS for 2-Hexanone yet. Suppliers usually send one with their quote. Request quotes

Safety questions

Quick answers about handling 2-Hexanone safely

Is 2-Hexanone hazardous?

2-Hexanone carries the GHS signal word "Danger". Main hazards: flammable liquid and vapour, may cause drowsiness or dizziness, suspected of damaging fertility. This summary is not an SDS, always read the supplier safety data sheet.

Which GHS pictograms apply to 2-Hexanone?

The GHS classification of 2-Hexanone shows 3 pictograms: GHS02 (flammable), GHS07 (harmful or irritant), GHS08 (serious health hazard).

What is the UN number of 2-Hexanone?

2-Hexanone is transported under UN 1224, hazard class 3, packing group III. Check the supplier SDS and the current ADR, IMDG or IATA rules before shipping.

How should 2-Hexanone be stored?

Fireproof. Separated from strong oxidants.

Where can I get the SDS for 2-Hexanone?

Ask the supplier for the safety data sheet of the exact grade you buy. Suppliers on CompoundList can attach their SDS to listings and send it with a quote. This page is a GHS classification summary, not an SDS.

GHS classification summary, not an SDS. Always check the supplier's SDS. Last updated 7 Oct 2026. Report an error

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