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Impurities and reference standards

2-Phenylpropionic acid

Also known as 2-Phenylpropanoic acid, Hydratropic acid, alpha-Methylphenylacetic acid

CAS 492-37-5Formula C9H10O2Molar mass 150.18 g/molEC 207-752-0
GHS signal word: Warning. Pictograms: Harmful or irritant 28 suppliers listed
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2-Phenylpropionic acid chemical structure, C9H10O2, CAS 492-37-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
492-37-5
Formula
C9H10O2
Molar mass
150.18 g/mol
EC number
207-752-0
HS code
291639
Category
Impurities and reference standards

What is 2-Phenylpropionic acid?

Plain description, key identifiers and synonyms

Hydratropic acid is a 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon. It has a role as a human xenobiotic metabolite. It is functionally related to a phenylacetic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-phenylpropanoic acid
CAS number
492-37-5Other or deprecated CAS: 2328-24-7, 7782-26-5
EC number
207-752-0
Molecular formula
C9H10O2
UNII
CH15E393A2
MDL number
MFCD00002650
InChIKey
YPGCWEMNNLXISK-UHFFFAOYSA-N
InChI
InChI=1S/C9H10O2/c1-7(9(10)11)8-5-3-2-4-6-8/h2-7H,1H3,(H,10,11)
SMILES (canonical and isomeric)
CC(C1=CC=CC=C1)C(=O)O

Synonyms

  • 2-Phenylpropanoic acid
  • Hydratropic acid
  • alpha-Methylphenylacetic acid
  • alpha-Methylbenzeneacetic acid
  • alpha-Phenylpropionic acid
  • alpha-methyl-benzeneacetic acid /OD/ 2-phenylpropionic acid
  • DL-2-Phenylpropionic Acid
  • (+/-)-2-Phenylpropionic acid
  • (+/-)-2-phenylpropanoic acid
  • Benzeneacetic acid, alpha-methyl-
  • Hydratropasaeure
  • (+/-)-Hydratropic acid
  • (+-)-Hydratropasaeure
  • Loxoprofen Impurity 12
  • (+-)-hydratropic acid
  • 2-Phenylpropionate
  • alpha-Phenylpropioic acid
  • a-Methylbenzeneacetic acid
  • 2-Phenyl-propionic acid
  • (R)-(-)-Hydratropic acid
  • DL-?-phenylpropionic acid
  • 2-Phenylpropionicacid
  • 2-phenyl propionic acid
  • alpha-Phenylpropioate
  • Benzeneacetic acid, alpha-methyl-, (R)-
Show all 34 synonyms
  • Benzeneacetic acid, alpha-methyl-, (S)-
  • DL-PPA
  • 2-phenyl propanoic acid
  • Propanoic acid, 2-phenyl
  • alpha-phenyl propionic acid
  • propanoic acid, 2-phenyl-
  • (?)-2-Phenylpropionic acid
  • DL-I<<-Phenylpropionic acid
  • (RS)-2-phenylpropionic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
150.18 g/molcalc.
Exact mass
150.0681 Dacalc.
LogP (octanol/water)
1.87calc.
Topological polar surface area
37.3 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.22calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

2-Phenylpropionic acid suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 28 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

28 suppliers in 6 countries

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2-Phenylpropionic acid price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Roles

  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • xenobiotic metabolite

Functional uses

  • Flavouring and nutrient

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Inactive in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 2-Phenylpropionic acid is traded under.

HS 2916.39Indicative HS code

Aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…

World exports in 2024
$706M
−6.8% vs 2023, imports $714M
2019 to 2024
Top exporters
  1. China49.0%
  2. India * partner reported16.2%
  3. Germany13.2%
Top importers
  1. India * partner reported14.5%
  2. United States12.2%
  3. Germany8.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 2-Phenylpropionic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 2-Phenylpropionic acid, based on the data on this page

What is 2-Phenylpropionic acid?

Hydratropic acid is a 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon. It has a role as a human xenobiotic metabolite. It is functionally related to a phenylacetic acid.

What is the CAS number of 2-Phenylpropionic acid?

The CAS registry number of 2-Phenylpropionic acid is 492-37-5. Other or deprecated CAS numbers: 2328-24-7, 7782-26-5.

What is the molecular formula and weight of 2-Phenylpropionic acid?

The molecular formula of 2-Phenylpropionic acid is C9H10O2 and its molar mass is 150.18 g/mol.

What is 2-Phenylpropionic acid used for?

Known uses and roles of 2-Phenylpropionic acid include animal metabolite, eukaryotic metabolite, human metabolite, human xenobiotic metabolite, mammalian metabolite and 3 more.

Is 2-Phenylpropionic acid hazardous?

2-Phenylpropionic acid carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 2-Phenylpropionic acid?

2-Phenylpropionic acid is usually classified under HS code 291639 (Aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 2-Phenylpropionic acid?

CompoundList lists 28 suppliers of 2-Phenylpropionic acid in China, United States, Canada, Germany and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 2-Phenylpropionic acid?

Suppliers quote 2-Phenylpropionic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 2-Phenylpropionic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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