CompoundList
Sign in
Synthetic aroma chemicals

4'-Methoxyacetophenone

Also known as 4-Methoxyacetophenone, 4-Acetylanisole, 1-(4-Methoxyphenyl)ethanone

CAS 100-06-1Formula C9H10O2Molar mass 150.18 g/molEC 202-815-9
GHS signal word: Warning. Pictograms: Harmful or irritant 48 suppliers listed
Get quotes Compare 48 suppliers
4'-Methoxyacetophenone chemical structure, C9H10O2, CAS 100-06-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystalline solid
Melting point
38.2 °C
Boiling point
254 °C
Density
1.0818 g/cm³ at 41 °C
Flash point
138 °C
HS code
291450
Category
Synthetic aroma chemicals
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is 4'-Methoxyacetophenone?

Plain description, key identifiers and synonyms

4-methoxyacetophenone is a member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4. It is a member of acetophenones and a monomethoxybenzene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(4-methoxyphenyl)ethanone
CAS number
100-06-1 CAS number cross-checkedOther or deprecated CAS: 1804943-43-8
EC numbers
202-815-9, 922-271-2
Molecular formula
C9H10O2
UNII
0IRH2BR587
MDL number
MFCD00008745
INCI name
METHOXYACETOPHENONE
InChIKey
NTPLXRHDUXRPNE-UHFFFAOYSA-N
InChI
InChI=1S/C9H10O2/c1-7(10)8-3-5-9(11-2)6-4-8/h3-6H,1-2H3
SMILES (canonical and isomeric)
CC(=O)C1=CC=C(C=C1)OC

Synonyms

  • 4-Methoxyacetophenone
  • 4-Acetylanisole
  • 1-(4-Methoxyphenyl)ethanone
  • Novatone
  • Linarodin
  • 1-(4-methoxyphenyl)ethan-1-one
  • Vananote
  • Ethanone, 1-(4-methoxyphenyl)-
  • 4-Methoxyphenyl methyl ketone
  • Acetophenone, 4'-methoxy-
  • p-Methoxyphenyl methyl ketone
  • Methyl p-methoxyphenyl ketone
  • 4-Methoxyacetofenon
  • Anisyl, p-, methyl ketone
  • p-Methoxyacetophenone
  • Acetanisole
  • p-Acetylanisole
  • p-methoxy acetophenone
  • Methyl 4-methoxyphenyl ketone
  • 4'-methoxy-acetophenone
  • 4-Acetoanisole
  • p-Metoxyacetophenone
  • p-methoxy-acetophenone
  • 4-methoxy acetophenone
  • 4-Methoxy-acetophenone
Show all 37 synonyms
  • para-Methoxyacetophenone
  • 1-(4-methoxyphenyl)ethanone-OCD3
  • Acetophenone, p-methoxy-
  • 1-acetyl-4-methoxybenzene
  • Epenone
  • 1-(4-methoxyphenyl)-ethanone
  • 1-(4-Methoxy D3 phenyl)ethanone
  • acetylanisole
  • 4-Methoxyphenylacetone, Mebeverine Hydrochloride Imp. A (Pharmeuropa)
  • p-methoxyactophenone
  • paramethoxyacetophenone
  • p -methoxyacetophenone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalline solidexp.
Odour
Pleasant odorexp.
Taste
Bitter and unpleasant tasteexp.
Melting point
38.2 °Cexp.
Boiling point
254 °Cexp.
Density
1.0818 g/cm³ at 41 °Cexp.
Flash point
138 °Cexp.
Solubility
Soluble in ethanol, diethyl ether, acetone and chloroformexp.
Vapour pressure
6.44 × 10⁻³ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
150.18 g/molcalc.
Exact mass
150.0681 Dacalc.
LogP (octanol/water)
1.9calc.
Topological polar surface area
26.3 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.22calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
Precautionary statements (13)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

4'-Methoxyacetophenone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 48 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

48 suppliers in 16 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

4'-Methoxyacetophenone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Reported uses (ppm):

Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#8333].

Useful in vanilla, nut, tobacco and butter flavors.

Perfumery (for floral odors), flavoring.

Industrial uses: Fragrance.

Consumer uses: Fragrance.

Cosmetic ingredient, INCI name METHOXYACETOPHENONE(perfuming)

Functional uses

  • Flavouring and nutrient
  • Fragrance

Cosmetic functions

  • Perfuming

How it is made

From anisole and acetyl chloride in the presence of aluminum chloride and carbon disulfide, from anisole and acetic acid in the presence of boron trifluoride.

It is prepared by Friedel-Crafts acetylation of anisole.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 4'-Methoxyacetophenone is traded under.

HS 2914.50Indicative HS code

Ketone-phenols and ketones with other oxygen function

World exports in 2024
$438M
+10.9% vs 2023, imports $420M
2019 to 2024
Top exporters
  1. China50.5%
  2. India * partner reported11.6%
  3. United States11.3%
Top importers
  1. United States20.8%
  2. Germany10.0%
  3. Netherlands8.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 4'-Methoxyacetophenone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 4'-Methoxyacetophenone, based on the data on this page

What is 4'-Methoxyacetophenone?

4-methoxyacetophenone is a member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4. It is a member of acetophenones and a monomethoxybenzene.

What is the CAS number of 4'-Methoxyacetophenone?

The CAS registry number of 4'-Methoxyacetophenone is 100-06-1. Other or deprecated CAS numbers: 1804943-43-8.

What is the molecular formula and weight of 4'-Methoxyacetophenone?

The molecular formula of 4'-Methoxyacetophenone is C9H10O2 and its molar mass is 150.18 g/mol.

What is 4'-Methoxyacetophenone used for?

Reported uses (ppm): Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#8333]. Useful in vanilla, nut, tobacco and butter flavors. Perfumery (for floral odors), flavoring. Industrial uses: Fragrance. Consumer uses: Fragrance.

Is 4'-Methoxyacetophenone hazardous?

4'-Methoxyacetophenone carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 4'-Methoxyacetophenone?

4'-Methoxyacetophenone is usually classified under HS code 291450 (Ketone-phenols and ketones with other oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 4'-Methoxyacetophenone?

CompoundList lists 48 suppliers of 4'-Methoxyacetophenone in China, India, United States, Hong Kong and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy 4'-Methoxyacetophenone in India?

10 suppliers in India list 4'-Methoxyacetophenone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of 4'-Methoxyacetophenone?

Suppliers quote 4'-Methoxyacetophenone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 4'-Methoxyacetophenone

Get quotes for 4'-Methoxyacetophenone

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell 4'-Methoxyacetophenone
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of 4'-Methoxyacetophenone with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/4-methoxyacetophenone-100-06-1" title="4'-Methoxyacetophenone structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Synthetic aroma chemicals or HS code 291450

48 suppliers
Free quotes, contact stays private
Get quotes