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Synthetic aroma chemicals

Acetamide

Also known as Ethanamide, Acetic acid amide, Methanecarboxamide

CAS 60-35-5Formula C2H5NOMolar mass 59.07 g/molEC 200-473-5
GHS signal word: Warning. Pictograms: Serious health hazard 116 suppliers listed
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Acetamide chemical structure, C2H5NO, CAS 60-35-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Deliquescent hexagonal crystals
Melting point
81.2 °C
Boiling point
222 °C
Density
1.16 g/cm³
Solubility
In water, 7.05 × 10⁺⁵ mg/L at 24.5 °C
HS code
292419
Category
Synthetic aroma chemicals
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Acetamide?

Plain description, key identifiers and synonyms

Acetamide is a member of the class of acetamides that results from the formal condensation of acetic acid with ammonia. It is a member of acetamides, a monocarboxylic acid amide and a N-acylammonia. It is a tautomer of an acetimidic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
acetamide
CAS number
60-35-5 CAS number cross-checkedOther or deprecated CAS: 27595-75-1, 74330-92-0
EC number
200-473-5
Molecular formula
C2H5NO
UNII
8XOE1JSO29
MDL number
MFCD00008023
InChIKey
DLFVBJFMPXGRIB-UHFFFAOYSA-N
InChI
InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)
SMILES (canonical and isomeric)
CC(=O)N

Synonyms

  • Ethanamide
  • Acetic acid amide
  • Methanecarboxamide
  • Acetimidic acid
  • Ethanimidic acid
  • Amid kyseliny octove
  • CH3CONH2
  • acetamido
  • Amide C2
  • Acetimidic acid (VAN)
  • acetoamide
  • Acetamides
  • n-acetylamine
  • imidoacetic acid
  • Acetamide, Purified
  • methane, carbamoyl-
  • Acetamide, >=98%
  • Acetamide, sublimed, 99%
  • Acetamide, ~99% (GC)
  • 4-02-00-00399 (Beilstein Handbook Reference)
  • Acetamide, analytical standard
  • Acetamide, crystalline, >=99%
  • Acetamide, >=98.0% (GC)
  • Acetamide, >=99.0% (GC)
  • Acetamide (6CI,7CI,8CI,9CI)
Show all 28 synonyms
  • Sdccgsbi-0049992.p002
  • Acetamide Solution in Water, 100ug/mL
  • Acetamide Solution in Water, 1000ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Deliquescent hexagonal crystalsexp.
Odour
Odorless when pure, but frequently has a mousy odorexp.
Taste
Pure acetamide has a bitter tasteexp.
Melting point
81.2 °Cexp.
Boiling point
222 °Cexp.
Density
1.16 g/cm³exp.
Solubility
In water, 7.05 × 10⁺⁵ mg/L at 24.5 °Cexp.
Vapour pressure
0.0182 mm Hg at 25 °C /OECD Guideline 104 (Vapor Pressure Curve)/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
59.07 g/molcalc.
Exact mass
59.0371 Dacalc.
LogP (octanol/water)
-0.51calc.
Topological polar surface area
43.09 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
4calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H351Suspected of causing cancer.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Acetamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 116 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

116 suppliers in 23 countries

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Acetamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis.

Organic synthesis (reactant, solvent, peroxide stabilizer), general solvent, lacquers, explosives, soldering flux, hygroscopic agent, wetting agent, penetrating agent.

It suppresses acid buildup in printing inks, lacquers, explosives, and perfumes. It is a mild moisturizer and is used as a softener for leather, textiles, paper, and certain plastics. ... Acetamide and substituted acetamide-containing thiourea can be used for treatment of herpes viruses. Derivatives can also be used as feeding behavior modifiers.

Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent.

Functional uses

  • Flavouring and nutrient

How it is made

Prepared by fractional distillation of ammonium acetate.

Interaction of ethyl acetate and ammonium hydroxide.

Acetamide can be produced by several methods. Ammonia reacts vigorously with acetyl halides or acetic anhydride to produce acetamide. Alkyl acetates also react with ammonia to yield acetamide. Dehydration of ammonium acetate is the standard procedure for preparation of acetamide. Finally, acetonitrile is hydrolyzed to yield acetamide in the presence of an acid or base catalyst.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 616-022-00-4

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Acetamide, Ref no: 1076, Annex ref: II/1076

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acetamide is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Acetamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acetamide, based on the data on this page

What is Acetamide?

Acetamide is a member of the class of acetamides that results from the formal condensation of acetic acid with ammonia. It is a member of acetamides, a monocarboxylic acid amide and a N-acylammonia. It is a tautomer of an acetimidic acid.

What is the CAS number of Acetamide?

The CAS registry number of Acetamide is 60-35-5. Other or deprecated CAS numbers: 27595-75-1, 74330-92-0.

What is the molecular formula and weight of Acetamide?

The molecular formula of Acetamide is C2H5NO and its molar mass is 59.07 g/mol.

What is Acetamide used for?

Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis.

Is Acetamide hazardous?

Acetamide carries the GHS signal word "Warning". Main hazards: suspected of causing cancer. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Acetamide?

Acetamide is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acetamide?

CompoundList lists 116 suppliers of Acetamide in China, United States, India, United Kingdom and 19 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Acetamide in India?

16 suppliers in India list Acetamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Acetamide?

Suppliers quote Acetamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acetamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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