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Central nervous system drugs

Acetophenazine

Also known as Acetophenazinum, Acetofenazina, 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethan-1-one

CAS 2751-68-0Formula C23H29N3O2SMolar mass 411.57 g/mol
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Acetophenazine chemical structure, C23H29N3O2S, CAS 2751-68-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2751-68-0
Formula
C23H29N3O2S
Molar mass
411.57 g/mol
HS code
293430
Category
Central nervous system drugs

What is Acetophenazine?

Plain description, key identifiers and synonyms

Acetophenazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the nitogen atom and an acetyl group at position 2. It has a role as a phenothiazine antipsychotic drug. It is a member of phenothiazines, a N-alkylpiperazine and a N-(2-hydroxyethyl)piperazine. It is functionally related to a 10H-phenothiazine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]ethanone
CAS number
2751-68-0 CAS number cross-checked
Molecular formula
C23H29N3O2S
UNII
8620H6K4QH
InChIKey
WNTYBHLDCKXEOT-UHFFFAOYSA-N
InChI
InChI=1S/C23H29N3O2S/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27/h2-3,5-8,17,27H,4,9-16H2,1H3
SMILES (canonical and isomeric)
CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCN(CC4)CCO

Synonyms

  • Acetophenazinum
  • Acetofenazina
  • 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethan-1-one
  • Ethanone, 1-(10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-10H-phenothiazin-2-yl)-
  • Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-
  • 1-(10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)-10H-phenothiazin-2-yl)ethan-1-one
  • 1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]ethanone
  • Acephenazinum
  • Acetophenazina
  • 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone
  • 10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl methyl ketone
  • Ketone, 10-(3-(4-(2-hydroxyethyl-1-piperazinyl)propyl)phenothiazin-2-yl methyl
  • Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl
  • 1-(10-(3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl)-10H-phenothiazin-2-yl)ethanone #

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
411.57 g/molcalc.
Exact mass
411.198 Dacalc.
LogP (octanol/water)
3.49calc.
Topological polar surface area
47.02 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
7calc.
Heavy atoms
29calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)Sc1ccccc1N2CCCN1CCNCC1

c1ccc2c(c1)Sc1ccccc1N2CCCN1CCNCC1

4 rings, 23 atoms, the 10-Piperazinylpropylphenothiazine ring system.

206 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Acetophenazine suppliers

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Acetophenazine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Roles

  • antipsychotic agent
  • central nervous system depressant
  • central nervous system drug
  • first generation antipsychotic
  • pharmaceutical
  • phenothiazine antipsychotic drug
  • psychotropic drug
  • tranquilizing drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acetophenazine is traded under.

HS 2934.30Indicative HS code

Compounds containing in the structure a phenothiazine ring-system (whether or not…

World exports in 2024
$89.3M
−7.1% vs 2023, imports $97M
2019 to 2024
Top exporters
  1. Germany21.6%
  2. France * partner reported14.6%
  3. China13.0%
Top importers
  1. United States14.2%
  2. Brazil12.7%
  3. India * partner reported10.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Acetophenazine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acetophenazine, based on the data on this page

What is Acetophenazine?

Acetophenazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the nitogen atom and an acetyl group at position 2. It has a role as a phenothiazine antipsychotic drug.

What is the CAS number of Acetophenazine?

The CAS registry number of Acetophenazine is 2751-68-0.

What is the molecular formula and weight of Acetophenazine?

The molecular formula of Acetophenazine is C23H29N3O2S and its molar mass is 411.57 g/mol.

What is Acetophenazine used for?

Known uses and roles of Acetophenazine include cns agents in pharmaceuticals, antipsychotic agent, central nervous system depressant, central nervous system drug, first generation antipsychotic and 4 more.

Is Acetophenazine hazardous?

No GHS hazard classification for Acetophenazine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Acetophenazine?

Acetophenazine is usually classified under HS code 293430 (Compounds containing in the structure a phenothiazine ring-system (whether or not…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acetophenazine?

Post a free request on CompoundList and suppliers of Acetophenazine will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Acetophenazine?

Suppliers quote Acetophenazine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acetophenazine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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