Central nervous system drugs

Many CNS drugs are potent at low doses, so content uniformity, particle size and polymorphic form are critical. Several classes, including benzodiazepines, barbiturates, stimulants, some anaesthetics and many opioids, are controlled substances under the international drug control conventions and national laws. Trading them requires licences for both buyer and seller and import and export permits for every shipment.

For non-controlled CNS APIs, confirm the pharmacopoeia grade, related substances, residual solvents, chiral purity where the drug is a single enantiomer, and the regulatory dossier status. For controlled products, CompoundList only allows contact between parties who can show the required licences, and listings may be restricted. When in doubt, check the controlled substances policy and ask the compliance team before posting a request.