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Vitamins and nutraceutical actives

alpha-Tocopherol succinate

Also known as alpha-Tocopheryl succinate, (+)-alpha-Tocopheryl succinate, d-alpha-Tocopherol acid succinate

CAS 4345-03-3Formula C33H54O5Molar mass 530.79 g/molEC 224-403-8
68 suppliers listed
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alpha-Tocopherol succinate chemical structure, C33H54O5, CAS 4345-03-3
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Powder
Melting point
76.1 to 77.2
Solubility
Less than 0.1 mg/mL at 64 °F
HS code
293628
Category
Vitamins and nutraceutical actives
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is alpha-Tocopherol succinate?

Plain description, key identifiers and synonyms

Tocopherol succinate is a hemisuccinate and a tocol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid
CAS number
4345-03-3 CAS number cross-checkedOther or deprecated CAS: 17407-37-3, 55134-51-5
EC numbers
224-403-8, 241-433-7
Molecular formula
C33H54O5
UNII
LU4B53JYVE
MDL number
MFCD00072055
INCI name
TOCOPHERYL SUCCINATE
InChIKey
IELOKBJPULMYRW-NJQVLOCASA-N
InChI
InChI=1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1
Canonical SMILES
Cc1c(C)c2c(c(C)c1OC(=O)CCC(=O)O)CCC(C)(CCCC(C)CCCC(C)CCCC(C)C)O2
Isomeric SMILES
CC1=C(C(=C(C2=C1O[C@](CC2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C)OC(=O)CCC(=O)O)C

Synonyms

  • alpha-Tocopheryl succinate
  • (+)-alpha-Tocopheryl succinate
  • d-alpha-Tocopherol acid succinate
  • Covitol 1210
  • alpha-Tocopheryl acid succinate
  • alpha-Vitamin E succinate
  • alpha-Tocopherol, succinate
  • alpha-Tocopherol hemisuccinate
  • 4-oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid
  • 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, hydrogen succinate, (+)-
  • Succinic acid, mono(2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl) ester, (+)-
  • 4-oxo-4-(((2R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl)oxy)butanoic acid
  • vitamin e succinate
  • D-alpha-Tocopherol succinate
  • tocopherol succinate
  • D-|A-Tocopherol succinate
  • D-alpha-Tocopheryl succinate
  • Vitamin E hemisuccinate
  • 4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoic acid
  • Alpha-tocopherol succinate, d-
  • a-Tocopheryl Succinate
  • Vitamine E succinate
  • alpha tocopheryl acid succinate
  • (+)-alpha-Tocopherol acid succinate
  • 4-oxo-4-{[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl]oxy}butanoic acid
Show all 34 synonyms
  • D-alpha tocopheryl acid succinate
  • 4-oxo-4-[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl]oxy-butanoic acid
  • Butanedioic acid,mono[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl] ester
  • CV 104
  • 3-{[(2R)-2-((4R,8R)-4,8,12-trimethyltridecyl)-2,5,7,8-tetramethylchroman-6-yl] oxycarbonyl}propanoic acid
  • Butanedioic acid, 1-((2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl) ester
  • Butanedioic acid, mono((2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl) ester
  • Tocopheryl succinate
  • d-a-tocopherol succinate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Powderexp.
Melting point
76.1 to 77.2exp.
Solubility
Less than 0.1 mg/mL at 64 °Fexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
530.79 g/molcalc.
Exact mass
530.3971 Dacalc.
LogP (octanol/water)
8.9calc.
Topological polar surface area
72.83 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
16calc.
Heavy atoms
38calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.76calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)CCCO2

c1ccc2c(c1)CCCO2

2 rings, 10 atoms, the Chroman ring system.

4,102 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

alpha-Tocopherol succinate suppliers

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All 68 suppliers
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Where suppliers are based

68 suppliers in 13 countries

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alpha-Tocopherol succinate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name TOCOPHERYL SUCCINATE(antioxidant)

Functional uses

  • Antioxidant
  • Flavouring and nutrient

Cosmetic functions

  • Antioxidant

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code alpha-Tocopherol succinate is traded under.

HS 2936.28Indicative HS code

Vitamin E and its derivatives

World exports in 2024
$2.27B
+26.5% vs 2023, imports $2.27B
2019 to 2024
Top exporters
  1. China54.5%
  2. Switzerland * partner reported15.5%
  3. Netherlands11.1%
Top importers
  1. United States21.2%
  2. Netherlands10.2%
  3. Germany10.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for alpha-Tocopherol succinate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about alpha-Tocopherol succinate, based on the data on this page

What is alpha-Tocopherol succinate?

Tocopherol succinate is a hemisuccinate and a tocol.

What is the CAS number of alpha-Tocopherol succinate?

The CAS registry number of alpha-Tocopherol succinate is 4345-03-3. Other or deprecated CAS numbers: 17407-37-3, 55134-51-5.

What is the molecular formula and weight of alpha-Tocopherol succinate?

The molecular formula of alpha-Tocopherol succinate is C33H54O5 and its molar mass is 530.79 g/mol.

What is alpha-Tocopherol succinate used for?

Known uses and roles of alpha-Tocopherol succinate include vitamins and supplements in pharmaceuticals, antioxidants in cosmetics and personal care, vitamins, minerals and nutrients in food and beverage, feed vitamins in animal feed and nutrition, antioxidant and 1 more.

Is alpha-Tocopherol succinate hazardous?

No GHS hazard classification for alpha-Tocopherol succinate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of alpha-Tocopherol succinate?

alpha-Tocopherol succinate is usually classified under HS code 293628 (Vitamin E and its derivatives). This is indicative, confirm it with your customs broker before shipping.

Where can I buy alpha-Tocopherol succinate?

CompoundList lists 68 suppliers of alpha-Tocopherol succinate in United States, China, Germany, Spain and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of alpha-Tocopherol succinate?

Suppliers quote alpha-Tocopherol succinate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle alpha-Tocopherol succinate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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