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Vitamins and nutraceutical actives

DL-alpha-Tocopherol

Also known as Ephanyl, alpha-Tocopherol, DL-, Vitamin E DL-alpha

CAS 10191-41-0Formula C29H50O2Molar mass 430.72 g/molEC 233-466-0
GHS signal word: Warning. Pictograms: Harmful or irritant 42 suppliers listed
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DL-alpha-Tocopherol chemical structure, C29H50O2, CAS 10191-41-0
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Slightly viscous, pale yellow oil
Melting point
2.5 to 3.5
Boiling point
200 to 220
Density
0.950 at 25 °C/4 °C
Solubility
Practically insoluble in water, freely soluble in oils, fats, acetone, alcohol, chlorofo…
HS code
293628
Category
Vitamins and nutraceutical actives
Illustrative photo, sealed amber glass ampoules on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is DL-alpha-Tocopherol?

Plain description, key identifiers and synonyms

2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol is a tocopherol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
CAS number
10191-41-0 CAS number cross-checkedOther or deprecated CAS: 113085-06-6, 1411583-24-8, 18920-62-2, 2074-53-5, 59-02-9
EC number
233-466-0
Molecular formula
C29H50O2
UNII
7QWA1RIO01
MDL number
MFCD00072045, MFCD00072051
InChIKey
GVJHHUAWPYXKBD-UHFFFAOYSA-N
InChI
InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
SMILES (canonical and isomeric)
CC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C

Synonyms

  • Ephanyl
  • alpha-Tocopherol, DL-
  • Vitamin E DL-alpha
  • DL-5,7,8-trimethyltocol
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
  • Ronotec df 120
  • Irganox e 210
  • Uvinul 2000ao
  • INS NO.307C
  • rac-alpha-tocopherol
  • 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
  • 5-17-04-00168 (Beilstein Handbook Reference)
  • 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
  • DLalphaTocopherol
  • allracalphaTocopherol
  • alphaTocopherol, DL
  • DLallracalphaTocopherol
  • alpha-Tocopherol, DL-(II)
  • 6Chromanol, 2,5,7,8tetramethyl2(4,8,12trimethyltridecyl)
  • 3,4Dihydro2,5,7,8tetramethyl2(4,8,12trimethyltridecyl)2Hbenzopyran6ol
  • alpha-tochopherol
  • dl-|A-tocopherol
  • (+/-)-alpha-Tocopherol
  • Tocopheroxy radical
  • all-rac-alpha-Tocopherol
Show all 33 synonyms
  • Aquasol E
  • a-Tocopherol
  • dl-a-Tocopherol
  • DL-alpha tocopherol
  • 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
  • Antisterility vitamin
  • (2S, 4'S, 8'R)-alpha-Tocopherol
  • DL-alpha-Tocopherol (Standard)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Slightly viscous, pale yellow oilexp.
Melting point
2.5 to 3.5exp.
Boiling point
200 to 220exp.
Density
0.950 at 25 °C/4 °Cexp.
Solubility
Practically insoluble in water, freely soluble in oils, fats, acetone, alcohol, chloroform, ether, other fat solventsexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
430.72 g/molcalc.
Exact mass
430.3811 Dacalc.
LogP (octanol/water)
8.84calc.
Topological polar surface area
29.46 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
12calc.
Heavy atoms
31calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.79calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)CCCO2

c1ccc2c(c1)CCCO2

2 rings, 10 atoms, the Chroman ring system.

4,102 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H317May cause an allergic skin reaction.
Precautionary statements (8)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

DL-alpha-Tocopherol suppliers

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Where suppliers are based

42 suppliers in 14 countries

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DL-alpha-Tocopherol price

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Uses and applications

What the substance is used for, by industry and function

All-rac-alpha-tocopherol is mainly used as an antioxidant in fats and oils and in feedingstuffs rich in oils and fats.

There are several forms of vitamin E available commercially (including dl-alpha-tocopherol). These are available as nutritional supplements or in functional and fortified foods.

Laboratory chemicals, manufacture of substances.

Industrial uses: Fragrance, Intermediate, Other.

Consumer uses: Other, Fragrance.

Use classes: Preservatives and Antioxidants, Safer Chemical Classes, Food additives, Cosmetics.

Functional uses

  • Antioxidant
  • Fragrance
  • Preservative
  • Softener and conditioner

Pharmacology

dl-alpha-Tocopherol is a synthetic form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04)

How it is made

It is synthesised from a mixture of toluene and 2,3,5-trimethyl-hydroquinone that reacts with isophytol to all-rac-alpha-tocopherol using iron in the presence of hydrogen chloride gas as catalyst. The reaction mixture obtained is filtered and extracted with aqueous caustic soda. Toluene is removed by evaporation and the residue (all-rac-alpha-tocopherol) is purified by vacuum distillation.

It is chemically synthesized by condensing racemic isophytol with trimethyl hydroquinone.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • Safer Choice ingredient list (USA)
  • TSCA inventory (USA)
    Status: Active in US commerce

Health and food

  • Food additive

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code DL-alpha-Tocopherol is traded under.

HS 2936.28Indicative HS code

Vitamin E and its derivatives

World exports in 2024
$2.27B
+26.5% vs 2023, imports $2.27B
2019 to 2024
Top exporters
  1. China54.5%
  2. Switzerland * partner reported15.5%
  3. Netherlands11.1%
Top importers
  1. United States21.2%
  2. Netherlands10.2%
  3. Germany10.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for DL-alpha-Tocopherol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about DL-alpha-Tocopherol, based on the data on this page

What is DL-alpha-Tocopherol?

2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol is a tocopherol.

What is the CAS number of DL-alpha-Tocopherol?

The CAS registry number of DL-alpha-Tocopherol is 10191-41-0. Other or deprecated CAS numbers: 113085-06-6, 1411583-24-8, 18920-62-2.

What is the molecular formula and weight of DL-alpha-Tocopherol?

The molecular formula of DL-alpha-Tocopherol is C29H50O2 and its molar mass is 430.72 g/mol.

What is DL-alpha-Tocopherol used for?

All-rac-alpha-tocopherol is mainly used as an antioxidant in fats and oils and in feedingstuffs rich in oils and fats. There are several forms of vitamin E available commercially (including dl-alpha-tocopherol). These are available as nutritional supplements or in functional and fortified foods.

Is DL-alpha-Tocopherol hazardous?

DL-alpha-Tocopherol carries the GHS signal word "Warning". Main hazards: may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of DL-alpha-Tocopherol?

DL-alpha-Tocopherol is usually classified under HS code 293628 (Vitamin E and its derivatives). This is indicative, confirm it with your customs broker before shipping.

Where can I buy DL-alpha-Tocopherol?

CompoundList lists 42 suppliers of DL-alpha-Tocopherol in China, United States, Germany, United Kingdom and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy DL-alpha-Tocopherol in India?

2 suppliers in India list DL-alpha-Tocopherol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of DL-alpha-Tocopherol?

Suppliers quote DL-alpha-Tocopherol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle DL-alpha-Tocopherol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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