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(-)-Asparagine

Also known as L-asparagine, asparagine, Aspartamic acid

CAS 70-47-3Formula C4H8N2O3Molar mass 132.12 g/molEC 200-735-9
(-)-Asparagine chemical structure, C4H8N2O3, CAS 70-47-3
2D chemical structure

Key facts

What buyers check first

Appearance
Orthorhombic bisphenoidal crystals
Melting point
234 to 235
Density
1.543 g/cm³ at 15/4 °C
Solubility
In water, 2.94 × 10⁺⁴ mg/L at 25 °C
HS code
292419
Category
Amino acids and derivatives
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is (-)-Asparagine?

Plain description, key identifiers and synonyms

L-asparagine is an optically active form of asparagine having L-configuration. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite and a human metabolite. It is a L-alpha-amino acid, an asparagine, an aspartate family amino acid and a proteinogenic amino acid. It is a conjugate base of a L-asparaginium. It is a conjugate acid of a L-asparaginate. It is an enantiomer of a D-asparagine. It is a tautomer of a L-asparagine zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2,4-diamino-4-oxobutanoic acid
CAS number
70-47-3 CAS number cross-checkedOther or deprecated CAS: 3130-87-8, 5794-13-8
EC number
200-735-9
Molecular formula
C4H8N2O3
UNII
5Z33R5TKO7
MDL number
MFCD00064401
INCI name
ASPARAGINE
InChIKey
DCXYFEDJOCDNAF-REOHCLBHSA-N
InChI
InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1
Canonical SMILES
NC(=O)CC(N)C(=O)O
Isomeric SMILES
C([C@@H](C(=O)O)N)C(=O)N

Synonyms

  • L-asparagine
  • asparagine
  • Aspartamic acid
  • (S)-asparagine
  • agedoite
  • altheine
  • Asparamide
  • Crystal VI
  • asparagine acid
  • (S)-2,4-diamino-4-oxobutanoic acid
  • L-Aspartamine
  • alpha-aminosuccinamic acid
  • L-Asparagine anhydrous
  • 2-Aminosuccinamic acid
  • aspartic acid beta-amide
  • L-2,4-diamino-4-oxobutanoic acid
  • (2S)-2-amino-3-carbamoylpropanoic acid
  • Aspartic acid amide
  • L-2-aminosuccinamic acid
  • (2S)-2,4-diamino-4-oxobutanoic acid
  • Asparagine anhydrous
  • L-Asn
  • 2-aminosuccinamic acid, L-
  • butanoic acid, 2,4-diamino-4-oxo-, (S)-
  • L-Asparagin
Show all 37 synonyms
  • L-aspartic acid beta-amide
  • L-beta-asparagine
  • 2,4-diamino-4-oxobutanoic acid, (S)-
  • (S)-2-amino-3-carbamoylpropanoic acid
  • (2S)-4-amino-2-azaniumyl-4-oxobutanoate
  • 2,4-diamino-4-oxobutanoic acid
  • 2-Amino-3-carbamoylpropanoic acid
  • H-Asn-OH
  • Asparagine, L-
  • ASN
  • L-b-Asparagine
  • Asparagine (VAN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Orthorhombic bisphenoidal crystalsexp.
Melting point
234 to 235exp.
Density
1.543 g/cm³ at 15/4 °Cexp.
Solubility
In water, 2.94 × 10⁺⁴ mg/L at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
132.12 g/molcalc.
Exact mass
132.0535 Dacalc.
LogP (octanol/water)
-1.73calc.
Topological polar surface area
106.4 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
9calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

(-)-Asparagine suppliers

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All 127 suppliers
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Where suppliers are based

127 suppliers in 21 countries

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(-)-Asparagine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Biochemical research, preparation of culture media, medicine.

Synthesis of acrylamide.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name ASPARAGINE(antistatic, hair conditioning, fragrance, skin conditioning)

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • animal metabolite
  • bacterial metabolite
  • eukaryotic metabolite
  • food component
  • fungal metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • micronutrient
  • mouse metabolite
  • nutraceutical
  • nutrient
  • pharmaceutical
  • physiological role
  • plant metabolite
  • prokaryotic metabolite

Functional uses

  • Anti-static agent
  • Deodorizer
  • Flavouring and nutrient
  • Softener and conditioner

Cosmetic functions

  • Antistatic
  • Fragrance
  • Hair conditioning
  • Skin conditioning

Pharmacology

Asparagine is a non-essential amino acid in humans, Asparagine is a beta-amido derivative of aspartic acid and plays an important role in the biosynthesis of glycoproteins and other proteins. A metabolic precursor to aspartate, Asparagine is a nontoxic carrier of residual ammonia to be eliminated from the body. Asparagine acts as diuretic. (NCI04)

How it is made

Produced by direct fermentation of carbohydrates

Isolated as a byproduct from the production of potato starch. A simple synthesis of L-asparagine from L-aspartic acid which is esterified to the beta methylester followed by treatment with ammonia.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (-)-Asparagine is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (-)-Asparagine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (-)-Asparagine, based on the data on this page

What is (-)-Asparagine?

L-asparagine is an optically active form of asparagine having L-configuration. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of (-)-Asparagine?

The CAS registry number of (-)-Asparagine is 70-47-3. Other or deprecated CAS numbers: 3130-87-8, 5794-13-8.

What is the molecular formula and weight of (-)-Asparagine?

The molecular formula of (-)-Asparagine is C4H8N2O3 and its molar mass is 132.12 g/mol.

What is (-)-Asparagine used for?

Biochemical research, preparation of culture media, medicine. Synthesis of acrylamide. Use classes: Cosmetics.

Is (-)-Asparagine hazardous?

No GHS hazard classification for (-)-Asparagine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of (-)-Asparagine?

(-)-Asparagine is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (-)-Asparagine?

CompoundList lists 127 suppliers of (-)-Asparagine in China, United States, Germany, Spain and 17 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy (-)-Asparagine in India?

2 suppliers in India list (-)-Asparagine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of (-)-Asparagine?

Suppliers quote (-)-Asparagine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (-)-Asparagine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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