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Analgesics and anti-inflammatories

Aspirin

Also known as Acetylsalicylic acid, 2-Acetoxybenzoic acid, 2-(Acetyloxy)benzoic acid

CAS 50-78-2Formula C9H8O4Molar mass 180.16 g/molEC 200-064-1
GHS signal word: Warning. Pictograms: Harmful or irritant 228 suppliers listed Drug substance
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Aspirin chemical structure, C9H8O4, CAS 50-78-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Monoclinic tablets or needle-like crystals
Melting point
135 °C
Boiling point
140 °C
Density
1.4 g/cm³
Flash point
250 °C
HS code
291822
Category
Analgesics and anti-inflammatories
UN number
UN 2811
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Aspirin?

Plain description, key identifiers and synonyms

Acetylsalicylic acid is a member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity. It has a role as a geroprotector, a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, a prostaglandin antagonist, an anticoagulant, a platelet aggregation inhibitor, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, a teratogenic agent, a plant activator, an EC 1.1.1.188 (prostaglandin-F synthase) inhibitor and a drug allergen. It is a member of phenyl acetates, a member of benzoic acids and a member of salicylates. It is functionally related to a salicylic acid. It is a conjugate acid of an acetylsalicylate.

Aspirin is a medication used to treat pain and decrease the risk of heart disease.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-acetyloxybenzoic acid
CAS number
50-78-2 CAS number cross-checkedOther or deprecated CAS: 11126-35-5, 98201-60-6
EC number
200-064-1
Molecular formula
C9H8O4
UNII
R16CO5Y76E
MDL number
MFCD00002430
INCI name
ACETYLSALICYLIC ACID
InChIKey
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
InChI
InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
SMILES (canonical and isomeric)
CC(=O)OC1=CC=CC=C1C(=O)O

Synonyms

  • Acetylsalicylic acid
  • 2-Acetoxybenzoic acid
  • 2-(Acetyloxy)benzoic acid
  • Acylpyrin
  • O-Acetylsalicylic acid
  • o-Acetoxybenzoic acid
  • Acenterine
  • Acetophen
  • Ecotrin
  • Salicylic acid acetate
  • Aceticyl
  • Acetosalin
  • Polopiryna
  • Aspirdrops
  • Pharmacin
  • Premaspin
  • Salcetogen
  • Acetonyl
  • Benaspir
  • Empirin
  • Endydol
  • Measurin
  • Rhodine
  • Saletin
  • Temperal
Show all 39 synonyms
  • Adiro
  • Ecolen
  • Acetosalic acid
  • Rheumintabletten
  • Solprin acid
  • o-Carboxyphenyl acetate
  • Acidum acetylsalicylicum
  • Benzoic acid, 2-(acetyloxy)-
  • 2-acetyloxybenzoic acid
  • Enterosarine
  • Acetisal
  • Acetylsal
  • Aspirine
  • Bialpirina

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Monoclinic tablets or needle-like crystalsexp.
Odour
Odorless, but in moist air it is gradually hydrolyzed and acquires odor of acetic acidexp.
Melting point
135 °Cexp.
Boiling point
140 °Cexp.
Density
1.4 g/cm³exp.
Flash point
250 °Cexp.
Solubility
1 g sol in: 300 mL water at 25 °C, 100 mL water at 37 °C, 5 mL alcohol, 17 mL chloroform, 10-15 mL ether, less sol in anhydrous etherexp.
Vapour pressure
2.52 × 10⁻⁵ mm Hg at 25 °C (calc)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
180.16 g/molcalc.
Exact mass
180.0423 Dacalc.
LogP (octanol/water)
1.31calc.
Topological polar surface area
63.6 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
13calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.11calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2811

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Aspirin suppliers

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All 228 suppliers
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Where suppliers are based

228 suppliers in 47 countries

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Aspirin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Analgesic, antipyretic, anti-inflammatory, antithrombotic.

Chemical profile: Virtually all aspirin is used in pharmaceutical products in aspirin tablets or in concert with other ingredients (1981).

Use classes: Pharmaceuticals, Animal Drugs.

Cosmetic ingredient, INCI name ACETYLSALICYLIC ACID(exfoliating)

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antipyretics
  • Cyclooxygenase Inhibitors
  • Fibrinolytic Agents
  • Platelet Aggregation Inhibitors

Roles

  • analgesic
  • anti-anaemic agent
  • anti-arrhythmia drug
  • anti-asthmatic agent
  • anti-inflammatory agent
  • anti-ulcer drug
  • antiatherosclerotic agent
  • anticoagulant
  • antidepressant
  • antihypertensive agent
  • antineoplastic agent
  • antipyretic
  • cardiovascular drug
  • drug allergen
  • geroprotector
  • hypoglycemic agent
  • immunosuppressive agent
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • ophthalmology drug
  • plant activator
  • platelet aggregation inhibitor
  • prostaglandin antagonist
  • vulnerary

Functional uses

  • Pharmaceutical

Cosmetic functions

  • Exfoliating

Pharmacology

Aspirin is a Nonsteroidal Anti-inflammatory Drug and Platelet Aggregation Inhibitor. The mechanism of action of aspirin is as a Cyclooxygenase Inhibitor. The physiologic effect of aspirin is by means of Decreased Prostaglandin Production and Decreased Platelet Aggregation.

How it is made

Acetylsalicylic acid is prepared by reacting acetic anhydride with salicylic acid at a temperature of <90 °C either in a solvent (e.g., acetic acid or aromatic, acyclic, or chlorinated hydrocarbons) or by the addition of catalysts such as acids or tertiary amines.

Manufacture from salicylic acid and acetic anhydride. ... Crystallization from acetone.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Aspirin is traded under.

HS 2918.22Indicative HS code

O-Acetylsalicylic acid, its salts and esters

World exports in 2024
$67.1M
−8.4% vs 2023, imports $60.4M
2019 to 2024
Top exporters
  1. China29.5%
  2. Spain26.2%
  3. France * partner reported21.5%
Top importers
  1. United States27.4%
  2. Italy10.3%
  3. Germany9.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Aspirin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Aspirin, based on the data on this page

What is Aspirin?

Acetylsalicylic acid is a member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

What is the CAS number of Aspirin?

The CAS registry number of Aspirin is 50-78-2. Other or deprecated CAS numbers: 11126-35-5, 98201-60-6.

What is the molecular formula and weight of Aspirin?

The molecular formula of Aspirin is C9H8O4 and its molar mass is 180.16 g/mol.

What is Aspirin used for?

Therapeutic category: Analgesic, antipyretic, anti-inflammatory, antithrombotic. Chemical profile: Virtually all aspirin is used in pharmaceutical products in aspirin tablets or in concert with other ingredients (1981). Use classes: Pharmaceuticals, Animal Drugs.

Is Aspirin hazardous?

Aspirin carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Aspirin?

Aspirin is usually classified under HS code 291822 (O-Acetylsalicylic acid, its salts and esters). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Aspirin?

CompoundList lists 228 suppliers of Aspirin in China, United States, India, Germany and 43 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Aspirin in India?

31 suppliers in India list Aspirin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Aspirin?

Suppliers quote Aspirin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Aspirin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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