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Skin conditioning agents and actives

Creatinine

Also known as 2-Imino-1-methylimidazolidin-4-one, 1-Methylglycocyamidine, 1-Methylhydantoin-2-imide

CAS 60-27-5Formula C4H7N3OMolar mass 113.12 g/molEC 200-466-7
GHS signal word: Warning. Pictograms: Harmful or irritant 86 suppliers listed Drug substance
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Creatinine chemical structure, C4H7N3O, CAS 60-27-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
60-27-5
Formula
C4H7N3O
Molar mass
113.12 g/mol
EC number
200-466-7
HS code
293329
Category
Skin conditioning agents and actives

What is Creatinine?

Plain description, key identifiers and synonyms

Creatinine is a lactam obtained by formal cyclocondensation of creatine. It is a metabolite of creatine. It has a role as a diagnostic agent and a human metabolite. It is a lactam and an imidazolidinone. It is functionally related to a creatine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-amino-3-methyl-4H-imidazol-5-one
CAS number
60-27-5 CAS number cross-checked
EC number
200-466-7
Molecular formula
C4H7N3O
UNII
AYI8EX34EU
INCI name
1-METHYLHYDANTOIN-2-IMIDE
InChIKey
DDRJAANPRJIHGJ-UHFFFAOYSA-N
InChI
InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
SMILES (canonical and isomeric)
CN1CC(=O)N=C1N

Synonyms

  • 2-Imino-1-methylimidazolidin-4-one
  • 1-Methylglycocyamidine
  • 1-Methylhydantoin-2-imide
  • Kreatinin
  • Creatinine,heated
  • Kreatininum
  • 2-amino-1-methylimidazolin-4-one
  • 2-amino-3-methyl-4H-imidazol-5-one
  • 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one
  • 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-
  • creatinina
  • 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one
  • Creatinine (II)
  • Imidazolidin-4-one, 2-imino-1-methyl
  • Creatinine (usp-rs)
  • Creatine anhydride
  • 2-Imino-N-methylhydantoin
  • 2-Amino-1-methyl-2-imidazolin-4-one
  • 2-Amino-1-methyl-1,5-dihydroimidazol-4-one
  • 2-Amino-1-Methyl-4-Imidazolidinone
  • Creatinine (VAN) (8CI)
  • 4H-Imidazol-4-one, 2-imino-1,5-dihydro-1-methyl-
  • DivK1c_000351
  • Creatinine, anhydrous, >=98%
  • Creatinine, 98.5-102.0%
Show all 30 synonyms
  • 2-Imino-1-methyl-imidazolidin-4-one
  • 2-Imino-1-methyl-4-imidazolidinone #
  • Creatinine, NIST(R) SRM(R) 914a
  • Sdccgmls-0066864.p001
  • 4H-Imidazol-4-one,5-dihydro-1-methyl-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
113.12 g/molcalc.
Exact mass
113.0589 Dacalc.
LogP (octanol/water)
-1.23calc.
Topological polar surface area
58.69 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
8calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CN=CN1

O=C1CN=CN1

1 ring, 6 atoms, the Imidazolone ring system.

73 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H336May cause drowsiness or dizziness.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Creatinine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 86 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

86 suppliers in 20 countries

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Creatinine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name 1-METHYLHYDANTOIN-2-IMIDE(skin conditioning)

Roles

  • animal metabolite
  • diagnostic agent
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • pharmaceutical

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Pharmacology

Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Creatinine is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$1.43B
โˆ’7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Creatinine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Creatinine, based on the data on this page

What is Creatinine?

Creatinine is a lactam obtained by formal cyclocondensation of creatine. It is a metabolite of creatine. It has a role as a diagnostic agent and a human metabolite. It is a lactam and an imidazolidinone. It is functionally related to a creatine.

What is the CAS number of Creatinine?

The CAS registry number of Creatinine is 60-27-5.

What is the molecular formula and weight of Creatinine?

The molecular formula of Creatinine is C4H7N3O and its molar mass is 113.12 g/mol.

What is Creatinine used for?

Use classes: Cosmetics.

Is Creatinine hazardous?

Creatinine carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Creatinine?

Creatinine is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Creatinine?

CompoundList lists 86 suppliers of Creatinine in United States, China, India, Germany and 16 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Creatinine in India?

12 suppliers in India list Creatinine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Creatinine?

Suppliers quote Creatinine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Creatinine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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