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Screening compounds

Azosemide

Also known as Azosemid, Diart, Azosemida

CAS 27589-33-9Formula C12H11ClN6O2S2Molar mass 370.85 g/molEC 248-549-7
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Azosemide chemical structure, C12H11ClN6O2S2, CAS 27589-33-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
27589-33-9
Formula
C12H11ClN6O2S2
Molar mass
370.85 g/mol
EC number
248-549-7
HS code
293590
Category
Screening compounds

What is Azosemide?

Plain description, key identifiers and synonyms

Azosemide is a sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hypertension. It has a role as a loop diuretic. It is a member of thiophenes, a sulfonamide, a member of tetrazoles and a member of monochlorobenzenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide
CAS number
27589-33-9 CAS number cross-checked
EC number
248-549-7
Molecular formula
C12H11ClN6O2S2
UNII
MR40VT1L8Z
MDL number
MFCD00867321, MFCD30541344
InChIKey
HMEDEBAJARCKCT-UHFFFAOYSA-N
InChI
InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19)
SMILES (canonical and isomeric)
C1=CSC(=C1)CNC2=CC(=C(C=C2C3=NNN=N3)S(=O)(=O)N)Cl

Synonyms

  • Azosemid
  • Diart
  • Azosemida
  • Azosemidum
  • Luret
  • 2-Chloro-5-(1H-tetrazol-5-yl)-N(sup 4)-2-thenylsulfanilamide
  • Benzenesulfonamide, 2-chloro-5-(1H-tetrazol-5-yl)-4-((2-thienylmethyl)amino)-
  • 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazole
  • 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzene-1-sulfonamide
  • 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzene-1-sulfonamide
  • 5-(4-chloro-5-sulfamyl-2-thienylaminophenyl)tetrazole
  • 2-Chloro-5-(1H-tetrazol-5-yl)-4-((thien-2-ylmethyl)amino)benzenesulfonamide
  • 2-chloro-5-(2H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
  • C12H11ClN6O2S2
  • PLE 1053
  • 2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide
  • Sulfanilamide, 2-chloro-5-(1H-tetrazol-5-yl)-N(sup 4)-2-thenyl-
  • 2-Chloro-5-(2H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]benzenesulfonamide
  • Benzenesulfonamide, 2-chloro-5-(2H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]-
  • SK 110
  • 2-chloro-5-(1H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide
  • 2-Chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide
  • IWE
  • 2-Chloro-5-(1H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
  • Diart (TN)
Show all 27 synonyms
  • 5-(4'-Chloro-5'-sulfamoyl-2'-thenylaminophenyl)-tetrazole
  • Azosemide (JP17/USAN/INN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
370.85 g/molcalc.
Exact mass
370.0073 Dacalc.
LogP (octanol/water)
1.84calc.
Topological polar surface area
126.7 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
5calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.08calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1csc(CNc2ccccc2-c2nn[nH]n2)c1

c1csc(CNc2ccccc2-c2nn[nH]n2)c1

3 rings, 18 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Azosemide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 7 suppliers
7 of 7 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

7 suppliers in 5 countries

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Azosemide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Diuretics

Roles

  • diuretic
  • loop diuretic
  • pharmaceutical

Pharmacology

Azosemide is a monosulfamyl belonging to the class of loop diuretics. Azosemide inhibits sodium and chloride reabsorption throughout the thick ascending limb of the loop of Henle.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Azosemide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Azosemide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Azosemide, based on the data on this page

What is Azosemide?

Azosemide is a sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hypertension. It has a role as a loop diuretic.

What is the CAS number of Azosemide?

The CAS registry number of Azosemide is 27589-33-9.

What is the molecular formula and weight of Azosemide?

The molecular formula of Azosemide is C12H11ClN6O2S2 and its molar mass is 370.85 g/mol.

What is Azosemide used for?

Known uses and roles of Azosemide include building blocks in research and laboratory, screening compounds in research and laboratory, diuretic, loop diuretic, pharmaceutical and 1 more.

Is Azosemide hazardous?

No GHS hazard classification for Azosemide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Azosemide?

Azosemide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Azosemide?

CompoundList lists 7 suppliers of Azosemide in China, India, Japan, South Korea and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Azosemide in India?

1 supplier in India list Azosemide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Azosemide?

Suppliers quote Azosemide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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