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Antibiotics and anti-infectives

Bacitracin

Also known as Altracin, Fortracin, Bacitracina

CAS 1405-87-4Formula C66H103N17O16SMolar mass 1,422.72 g/molEC 215-786-2
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 35 suppliers listed Drug substance
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Bacitracin chemical structure, C66H103N17O16S, CAS 1405-87-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1405-87-4
Formula
C66H103N17O16S
Appearance
White to pale buff powder
Solubility
White to grayish-white powder. Slightly disagreeable odor. Somewhat less bitter than bac…
HS code
294190
Category
Antibiotics and anti-infectives
Illustrative photo, fine white powder in a white HDPE jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Bacitracin?

Plain description, key identifiers and synonyms

Bacitracin A is a homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin. It has a role as an antimicrobial agent and an antibacterial agent. It is a polypeptide and a homodetic cyclic peptide.

Bacitracin is a pharmaceutical drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
CAS number
1405-87-4 CAS number cross-checkedOther or deprecated CAS: 22601-59-8
EC numbers
215-786-2, 245-115-9
Molecular formula
C66H103N17O16S
UNII
DDA3RRX0P7
InChIKey
CLKOFPXJLQSYAH-ABRJDSQDSA-N
InChI
InChI=1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35-,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48-,52-,53-,54-/m0/s1
Canonical SMILES
CCC(C)C(N)C1=NC(C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC2CCCCNC(=O)C(CC(N)=O)NC(=O)C(CC(=O)O)NC(=O)C(Cc3cnc[nH]3)NC(=O)C(Cc3ccccc3)NC(=O)C(C(C)CC)NC(=O)C(CCCN)NC2=O)C(C)CC)CS1
Isomeric SMILES
CC[C@H](C)[C@H]1C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N[C@@H](C(=O)N1)CCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSC(=N2)[C@H]([C@@H](C)CC)N)CC(=O)N)CC(=O)O)CC3=CN=CN3)CC4=CC=CC=C4

Synonyms

  • Altracin
  • Fortracin
  • Bacitracina
  • Bacitracine
  • Bacitracinum
  • Parentracin
  • Baciim
  • Baci-rx
  • Baciliquin
  • Bacilliquin
  • Tropitracin
  • Baciferm 50
  • Penitracin
  • Topitracin
  • Zutracin
  • Albac 50
  • Bacitracin(non-injectable)
  • USAF CB-7
  • Ayfivin
  • Bacitracinum (Latin)
  • Mycitracin Triple Antibiotic First Aid Ointment Maximum Strength
  • Bacitraycin
  • OcuTracin
  • Ocu Tracin
  • Winco Bacitracin
Show all 39 synonyms
  • Ak Tracin
  • Leader Bacitracin
  • Rexall Antibiotic
  • Bacitracin, Zinc
  • Baci Rx
  • Zapotol Bacitracin
  • Zeba Rx
  • Zeba-Rx
  • Baci IM
  • Medichoice Bacitracin
  • Bacitracin 500units
  • Martinet, Bacitracine
  • Face Values Bacitracin
  • Family Care Bacitracin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White to pale buff powderexp.
Odour
Odorlessexp.
Taste
Very bitter tasteexp.
Solubility
White to grayish-white powder. Slightly disagreeable odor. Somewhat less bitter than bacitracin. UV max (dilute acetic acid): 318 nm, min: 280 nm. Solubility in water about 50 mg/mL. pH of saturated aqueous solution 3.5 to 5.0.exp.
Vapour pressure
Infitesimally low vapor pressure over the temperature range at which bacitracins are stableexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,422.72 g/molcalc.
Exact mass
1,421.7489 Dacalc.
LogP (octanol/water)
-1.68calc.
Topological polar surface area
530.9 Ųcalc.
Hydrogen bond donors
17calc.
Hydrogen bond acceptors
19calc.
Rotatable bonds
31calc.
Heavy atoms
100calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.64calc.
Formal charge
0calc.
Stereocentres
15calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CNC(=O)CNC(=O)C(Cc2cnc[nH]2)NC(=O)C(Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)C(NC(=O)CNC(=O)CNC(=O)CNC(=O)C2CSC=N2)CCCCN1

O=C1CNC(=O)CNC(=O)C(Cc2cnc[nH]2)NC(=O)C(Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)C(NC(=O)CNC(=O)CNC(=O)CNC(=O)C2CSC=N2)CCCCN1

4 rings, 65 atoms.

14 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bacitracin suppliers

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All 35 suppliers
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Where suppliers are based

35 suppliers in 10 countries

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Bacitracin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Bacitracin ... has been incorporated as an additive in feed for various purposes of growth and disease control at a concentration of from 1-100 g/900 kg feed.

Effective against many gram-positive bacteria, but ineffective against most aerobic gram-negative bacteria.

Food additive permitted in food for human consumption.

Veterinary: Used locally in wound powders and ointments, dermatologic preparations, eye and ear ointments, and as feed additives in swine and poultry rations for growth promotion (Bacitracins).

Use classes: Pharmaceuticals, Animal Drugs.

Pharmacological actions

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Local

Roles

  • antibacterial agent
  • antimicrobial agent
  • geroprotector
  • pharmaceutical
  • protective agent

Pharmacology

The physiologic effect of bacitracin is by means of Decreased Cell Wall Synthesis & Repair.

How it is made

Antibiotic polypeptide complex produced by Bacillus subtilis and Bacillus licheniformis, mixture of at least nine bacitracins of which bacitracin A is a major component.

Production: Johnson, Meleney, USA patent 2498165 (1950 to the United States Secretary of War), Freaney, Allen, USA patent 2828246 (1958 to Commercial Solvents0.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bacitracin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bacitracin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bacitracin, based on the data on this page

What is Bacitracin?

Bacitracin A is a homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl.

What is the CAS number of Bacitracin?

The CAS registry number of Bacitracin is 1405-87-4. Other or deprecated CAS numbers: 22601-59-8.

What is the molecular formula and weight of Bacitracin?

The molecular formula of Bacitracin is C66H103N17O16S and its molar mass is 1,422.72 g/mol.

What is Bacitracin used for?

Bacitracin ... has been incorporated as an additive in feed for various purposes of growth and disease control at a concentration of from 1-100 g/900 kg feed. Effective against many gram-positive bacteria, but ineffective against most aerobic gram-negative bacteria. Food additive permitted in food for human consumption.

Is Bacitracin hazardous?

Bacitracin carries the GHS signal word "Warning". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bacitracin?

Bacitracin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bacitracin?

CompoundList lists 35 suppliers of Bacitracin in China, India, United States, Australia and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bacitracin in India?

6 suppliers in India list Bacitracin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bacitracin?

Suppliers quote Bacitracin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bacitracin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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