CompoundList
Sign in
Fungicides

Bafilomycin A1

Also known as BafA1, Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-, MEGxm0_000385

CAS 88899-55-2Formula C35H58O9Molar mass 622.84 g/molEC 621-324-4
GHS signal word: Warning. Pictograms: Harmful or irritant 15 suppliers listed
Get quotes Compare 15 suppliers
Bafilomycin A1 chemical structure, C35H58O9, CAS 88899-55-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
88899-55-2
Formula
C35H58O9
Molar mass
622.84 g/mol
EC number
621-324-4
HS code
293220
Category
Fungicides

What is Bafilomycin A1?

Plain description, key identifiers and synonyms

Bafilomycin A1 is the most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. It has a role as a ferroptosis inhibitor, a fungicide, a toxin, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an apoptosis inducer, an EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor, a bacterial metabolite, a potassium ionophore and an autophagy inhibitor. It is a macrolide antibiotic, a member of oxanes and a cyclic hemiketal.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
CAS number
88899-55-2 CAS number cross-checked
EC number
621-324-4
Molecular formula
C35H58O9
MDL number
MFCD06795130
InChIKey
XDHNQDDQEHDUTM-JQWOJBOSSA-N
InChI
InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12+,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33+,35+/m0/s1
Canonical SMILES
COC1=CC(C)=CC(C)C(O)C(C)CC(C)=CC=CC(OC)C(C(C)C(O)C(C)C2(O)CC(O)C(C)C(C(C)C)O2)OC1=O
Isomeric SMILES
C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C

Synonyms

  • BafA1
  • Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-
  • MEGxm0_000385
  • ACon0_000813

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
622.84 g/molcalc.
Exact mass
622.4081 Dacalc.
LogP (octanol/water)
4.69calc.
Topological polar surface area
134.9 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
9calc.
Rotatable bonds
7calc.
Heavy atoms
44calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.74calc.
Formal charge
0calc.
Stereocentres
12calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC=CCCCCC=CC=CCC(CCCC2CCCCO2)O1

O=C1C=CC=CCCCCC=CC=CCC(CCCC2CCCCO2)O1

2 rings, 26 atoms.

21 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bafilomycin A1 suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 15 suppliers
15 of 15 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

15 suppliers in 6 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Bafilomycin A1 price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antifungal Agents
  • Enzyme Inhibitors

Roles

  • antifungal agent
  • antimicrobial agent
  • apoptosis inducer
  • autophagy inhibitor
  • bacterial metabolite
  • biophysical role
  • enzyme inhibitor
  • ferroptosis inhibitor
  • fungicide
  • ionophore
  • membrane transport modulator
  • metabolite
  • pesticide
  • poison
  • potassium ionophore
  • prokaryotic metabolite
  • toxin

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bafilomycin A1 is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bafilomycin A1 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bafilomycin A1, based on the data on this page

What is Bafilomycin A1?

Bafilomycin A1 is the most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.

What is the CAS number of Bafilomycin A1?

The CAS registry number of Bafilomycin A1 is 88899-55-2.

What is the molecular formula and weight of Bafilomycin A1?

The molecular formula of Bafilomycin A1 is C35H58O9 and its molar mass is 622.84 g/mol.

What is Bafilomycin A1 used for?

Known uses and roles of Bafilomycin A1 include fungicides in agriculture and crop protection, biochemical and pharmacological tools in research and laboratory, antifungal agent, antimicrobial agent, apoptosis inducer and 16 more.

Is Bafilomycin A1 hazardous?

Bafilomycin A1 carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bafilomycin A1?

Bafilomycin A1 is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bafilomycin A1?

CompoundList lists 15 suppliers of Bafilomycin A1 in United States, China, United Kingdom, Australia and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Bafilomycin A1?

Suppliers quote Bafilomycin A1 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bafilomycin A1

Get quotes for Bafilomycin A1

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Bafilomycin A1
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Bafilomycin A1 with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/bafilomycin-a1-88899-55-2" title="Bafilomycin A1 structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Fungicides or HS code 293220

15 suppliers
Free quotes, contact stays private
Get quotes