Bambuterol
Also known as Bambuterolum, [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate, (+-)-5-(2-(tert-Butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate)
Key facts
What buyers check first
- CAS number
- 81732-65-2
- Formula
- C18H29N3O5
- Molar mass
- 367.45 g/mol
- HS code
- 292429
- Category
- Respiratory, allergy and digestive drugs
What is Bambuterol?
Plain description, key identifiers and synonyms
Bambuterol is a carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline. It has a role as a beta-adrenergic agonist, a bronchodilator agent, a sympathomimetic agent, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an anti-asthmatic drug, a prodrug and a tocolytic agent. It is a carbamate ester and a member of phenylethanolamines. It is functionally related to a terbutaline.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate
- CAS number
- 81732-65-2 CAS number cross-checkedOther or deprecated CAS: 81732-46-9
- Molecular formula
- C18H29N3O5
- UNII
- Y1850G1OVC
- InChIKey
- ANZXOIAKUNOVQU-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H29N3O5/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7/h8-10,15,19,22H,11H2,1-7H3
- SMILES (canonical and isomeric)
- CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O
Synonyms
- Bambuterolum
- [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate
- (+-)-5-(2-(tert-Butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate)
- (3-(2-(tert-butylamino)-1-hydroxyethyl)-5-(dimethylcarbamoyloxy)phenyl) N,N-dimethylcarbamate
- 5-(2-(tert-butylamino)-1-hydroxyethyl)-3-phenylene bis(dimethylcarbamate)
- 3-(2-(tert-butylamino)-1-hydroxyethyl)-5-((dimethylcarbamoyl)oxy)phenyl N,N-dimethylcarbamate
- Bambuterol (INN)
- Oxeol
- 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate)
- (+/-)-Bambuterol, KWD-2183
- (+/-)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate)
- terbutaline bisdimethylcarbamate
- 5-(2-(tert-butylamino)-1-hydroxyethyl)-1,3-phenylene bis(dimethylcarbamate)
- 5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate)
- terbutaline bis(dimethylcarbamate)
- Bambuterol impurity 13
- ()-Bambuterol, KWD-2183
- (RS)-5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 367.45 g/molcalc.Computed value |
|---|---|
| Exact mass | 367.2107 Dacalc.Computed value |
| LogP (octanol/water) | 2.23calc.Computed value |
| Topological polar surface area | 91.34 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 26calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.56calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Bambuterol suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Egypt, Cairo ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- Price on request
- India ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- India ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- United States ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- India, Surat ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- Turkey ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- Colombia, Cota ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- Australia ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
- Pakistan ManufacturerUnclaimed profileBambuterolGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
12 suppliers in 9 countries
- India3
- Australia1
- China1
- Colombia1
- Egypt1
- Hong Kong1
- and 3 more countries
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Bambuterol price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Bronchodilator Agents
Roles
- adrenergic agent
- adrenergic agonist
- anti-asthmatic agent
- anti-asthmatic drug
- antihypertensive agent
- beta-adrenergic agonist
- beta-adrenergic drug
- bronchodilator agent
- cardiovascular drug
- enzyme inhibitor
- neurotransmitter agent
- pharmaceutical
- pro-agent
- prodrug
- reproductive control drug
- sympathomimetic agent
- tocolytic agent
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Bambuterol is traded under.
Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other
- China32.3%
- Switzerland * partner reported13.6%
- Norway * partner reported12.8%
- United States15.9%
- Ireland15.8%
- Germany11.9%
* Partner reported figures, a lower bound.
The HS code shown for Bambuterol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Bambuterol, based on the data on this page
What is Bambuterol?
What is the CAS number of Bambuterol?
What is the molecular formula and weight of Bambuterol?
What is Bambuterol used for?
Is Bambuterol hazardous?
What is the HS code of Bambuterol?
Where can I buy Bambuterol?
Where can I buy Bambuterol in India?
What is the price of Bambuterol?
Guides for buyers
Practical guides that help when you source, ship or handle Bambuterol
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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