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Benzophenone-6

Also known as 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone, Bis(2-hydroxy-4-methoxyphenyl)methanone, Methanone, bis(2-hydroxy-4-methoxyphenyl)-

Benzophenone-6 chemical structure, C15H14O5, CAS 131-54-4
2D chemical structure

Key facts

What buyers check first

CAS number
131-54-4
Formula
C15H14O5
Appearance
Crystals
Melting point
139.1 °C
HS code
291450
Category
UV filters
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Benzophenone-6?

Plain description, key identifiers and synonyms

2,2'-Dihydroxy-4,4'-dimethoxybenzophenone is a member of benzophenones.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
bis(2-hydroxy-4-methoxyphenyl)methanone
CAS number
131-54-4 CAS number cross-checked
EC number
205-027-3
Molecular formula
C15H14O5
UNII
7813J9CS1G
MDL number
MFCD00009606
INCI name
BENZOPHENONE-6
InChIKey
SODJJEXAWOSSON-UHFFFAOYSA-N
InChI
InChI=1S/C15H14O5/c1-19-9-3-5-11(13(16)7-9)15(18)12-6-4-10(20-2)8-14(12)17/h3-8,16-17H,1-2H3
SMILES (canonical and isomeric)
COC1=CC(=C(C=C1)C(=O)C2=C(C=C(C=C2)OC)O)O

Synonyms

  • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone
  • Bis(2-hydroxy-4-methoxyphenyl)methanone
  • Methanone, bis(2-hydroxy-4-methoxyphenyl)-
  • Cyasorb UV 12
  • Uvinul D 49
  • 2,2-Dihydroxy-4,4-Dimethoxybenzophenone
  • Benzophenone 6
  • 4,4'-Dimethoxy-2,2'-dihydroxybenzophenone
  • Benzophenone, 2,2'-dihydroxy-4,4'-dimethoxy-
  • Helisorb 11
  • Benzophenone-6 (mart.)
  • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (8CI)
  • di2-hydroxy-4-methoxyphenyl ketone
  • 2-(2-hydroxy-4-methoxybenzoyl)-5-methoxyphenol
  • bis(2-hydroxy-4-methoxy-phenyl)methanone
  • 4,2'-dihydroxybenzophenone
  • Uvinul-d-49
  • Bis(2-hydroxy-4-methoxyphenyl) methanone
  • Benzophenone,2'-dihydroxy-4,4'-dimethoxy-
  • 2,2'-dihydroxy-4,4'-dimethoxy-benzophenone
  • 2,2/'-Dihydroxy-4,4/'-dimethoxybenzophenone
  • 2,2\'-Dihydroxy-4,4\'-dimethoxybenzophenone
  • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone, 98%
  • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone Solution in Acetonitrile, 1000ug/mL
  • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone Solution in Acetonitrile, 100ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Melting point
139.1 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
274.27 g/molcalc.
Exact mass
274.0841 Dacalc.
LogP (octanol/water)
2.35calc.
Topological polar surface area
75.99 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
4calc.
Heavy atoms
20calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(c1ccccc1)c1ccccc1

O=C(c1ccccc1)c1ccccc1

2 rings, 14 atoms, the Benzophenone ring system.

5,108 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (18)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Benzophenone-6 suppliers

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Benzophenone-6 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

As ultraviolet light absorber, especially in paints, plastics.

Table: Total uses/ranges for benzophenone-6 [Table#8581].

Use classes: Cosmetics.

Cosmetic ingredient, INCI name BENZOPHENONE-6(fragrance, uv absorber)

Functional uses

  • Deodorizer
  • UV stabilizer

Cosmetic functions

  • Fragrance
  • UV absorber

How it is made

Preparation: ... Hardy, Forster, United States of America patent 2773903 (1956 to American Cyanamide), Dayan, Roberts, Hahn, Stanley, United States of America patents 2853522 and 2853523 (both to General Aniline), Hosler, Storfer, United States of America patent 2928878 (1960 to American Cyanamide).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Benzophenone-6 is traded under.

HS 2914.50Indicative HS code

Ketone-phenols and ketones with other oxygen function

World exports in 2024
$438M
+10.9% vs 2023, imports $420M
2019 to 2024
Top exporters
  1. China50.5%
  2. India * partner reported11.6%
  3. United States11.3%
Top importers
  1. United States20.8%
  2. Germany10.0%
  3. Netherlands8.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Benzophenone-6 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Benzophenone-6, based on the data on this page

What is Benzophenone-6?

2,2'-Dihydroxy-4,4'-dimethoxybenzophenone is a member of benzophenones.

What is the CAS number of Benzophenone-6?

The CAS registry number of Benzophenone-6 is 131-54-4.

What is the molecular formula and weight of Benzophenone-6?

The molecular formula of Benzophenone-6 is C15H14O5 and its molar mass is 274.27 g/mol.

What is Benzophenone-6 used for?

As ultraviolet light absorber, especially in paints, plastics. Table: Total uses/ranges for benzophenone-6 [Table#8581]. Use classes: Cosmetics.

Is Benzophenone-6 hazardous?

Benzophenone-6 carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Benzophenone-6?

Benzophenone-6 is usually classified under HS code 291450 (Ketone-phenols and ketones with other oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Benzophenone-6?

CompoundList lists 21 suppliers of Benzophenone-6 in China, United States, United Kingdom, Netherlands and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Benzophenone-6?

Suppliers quote Benzophenone-6 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Benzophenone-6

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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