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Bixafen chemical structure, C18H12Cl2F3N3O, CAS 581809-46-3
2D chemical structure

Key facts

What buyers check first

CAS number
581809-46-3
Formula
C18H12Cl2F3N3O
Molar mass
414.21 g/mol
EC number
642-423-9
HS code
293319
Category
Fungicides

What is Bixafen?

Plain description, key identifiers and synonyms

Bixafen is an aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4'-dichloro-5-fluorobiphenyl-2-amine. A fungicide for use in cereals for key stem and leaf disease control including strobilurin-resistant septoria. It has a role as an EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor and an antifungal agrochemical. It is a member of biphenyls, a dichlorobenzene, a member of pyrazoles, an organofluorine compound, an aromatic amide and an anilide fungicide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[2-(3,4-dichlorophenyl)-4-fluorophenyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
CAS number
581809-46-3 CAS number cross-checked
EC number
642-423-9
Molecular formula
C18H12Cl2F3N3O
UNII
28XK2L8M3B
MDL number
MFCD16652583
InChIKey
LDLMOOXUCMHBMZ-UHFFFAOYSA-N
InChI
InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)
SMILES (canonical and isomeric)
CN1C=C(C(=N1)C(F)F)C(=O)NC2=C(C=C(C=C2)F)C3=CC(=C(C=C3)Cl)Cl

Synonyms

  • bixafene
  • Aviator xpro
  • Boogie xpro
  • Siltra xpro
  • Skyway xpro
  • Variano xpro
  • n-(3',4'-dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide
  • N-(3,4-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
  • N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide
  • n-(3',4'-dichloro-5-fluoro[1,1'-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide
  • N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
  • N-(2-(3,4-Dichlorophenyl)-4-fluorophenyl)-3-difluoromethyl-1-methylpyrazole-4-carboxylic acid amide
  • N-(3',4'-dichloro-5-fluoro(1,1'-biphenyl)-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide
  • N-(3',4'-Dichloro-5-fluoro-[1,1'-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide
  • N-[2-(3,4-dichlorophenyl)-4-fluorophenyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
  • Bixafen|
  • C18H12Cl2F3N3O
  • Bixafen 100 |Ig/mL in Acetonitrile
  • Bixafen 100 microg/mL in Acetonitrile
  • N-[2-(3,4-dichlorophenyl)-4-fluoro-phenyl]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide
  • Bixafen, PESTANAL(R), analytical standard
  • 1H-Pyrazole-4-carboxamide, N-(3',4'-dichloro-5-fluoro[1,1'-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-
  • N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
414.21 g/molcalc.
Exact mass
413.031 Dacalc.
LogP (octanol/water)
5.72calc.
Topological polar surface area
46.92 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
4calc.
Heavy atoms
27calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.11calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1ccccc1-c1ccccc1)c1cn[nH]c1

O=C(Nc1ccccc1-c1ccccc1)c1cn[nH]c1

3 rings, 20 atoms.

10 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H303 + H313 + H333May be harmful if swallowed. May be harmful in contact with skin. May be harmful if inhaled.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (6)
  • P273Avoid release to the environment.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P317If on skin: Get medical help.
  • P304 + P317If inhaled: Get medical help.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bixafen suppliers

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Bixafen price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pesticides, Fungicides.

Roles

  • agrochemical
  • antifungal agent
  • antifungal agrochemical
  • antimicrobial agent
  • enzyme inhibitor
  • fungicide
  • pesticide

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bixafen is traded under.

HS 2933.19Indicative HS code

Compounds containing an unfused pyrazole ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$3.44B
โˆ’22.6% vs 2023, imports $6.66B
2019 to 2024
Top exporters
  1. China21.6%
  2. Switzerland * partner reported20.5%
  3. Germany19.0%
Top importers
  1. Slovenia38.4%
  2. Portugal14.1%
  3. Brazil13.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bixafen is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bixafen, based on the data on this page

What is Bixafen?

Bixafen is an aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4'-dichloro-5-fluorobiphenyl-2-amine. A fungicide for use in cereals for key stem and leaf disease control including strobilurin-resistant septoria.

What is the CAS number of Bixafen?

The CAS registry number of Bixafen is 581809-46-3.

What is the molecular formula and weight of Bixafen?

The molecular formula of Bixafen is C18H12Cl2F3N3O and its molar mass is 414.21 g/mol.

What is Bixafen used for?

Use classes: Pesticides, Fungicides.

Is Bixafen hazardous?

Bixafen carries the GHS signal word "Warning". Main hazards: may be harmful if swallowed. may be harmful in contact with skin. may be harmful if inhaled, very toxic to aquatic life, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bixafen?

Bixafen is usually classified under HS code 293319 (Compounds containing an unfused pyrazole ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bixafen?

CompoundList lists 17 suppliers of Bixafen in Brazil, China, Argentina, France and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Bixafen?

Suppliers quote Bixafen on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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