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Oncology and immunology drugs

Bleomycin

Also known as Bleomicin, Bleocin, Bleomicina

CAS 11056-06-7Formula C55H84N17O21S3+Molar mass 1,415.58 g/mol
18 suppliers listed Drug substance
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Bleomycin chemical structure, C55H84N17O21S3+, CAS 11056-06-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
11056-06-7
Formula
C55H84N17O21S3+
Appearance
Colorless to yellow powder
Solubility
Colorless or yellowish powder which becomes bluish depending on copper content. Very sol…
HS code
294190
Category
Oncology and immunology drugs
Illustrative photo, fine white powder in a white HDPE jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Bleomycin?

Plain description, key identifiers and synonyms

Bleomycin is a mixture of glycopeptide antineoplastic antibiotics isolated from the bacterium Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA, these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium
CAS number
11056-06-7 CAS number cross-checked
Molecular formula
C55H84N17O21S3+
UNII
40S1VHN69B
InChIKey
OYVAGSVQBOHSSS-WXFSZRTFSA-O
InChI
InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29?,30?,34-,35-,36-,37?,38?,39?,40?,41-,42?,43?,53?,54?/m0/s1
Canonical SMILES
Cc1c(N)nc(C(CC(N)=O)NCC(N)C(N)=O)nc1C(=O)NC(C(=O)NC(C)C(O)C(C)C(=O)NC(C(=O)NCCc1nc(-c2nc(C(=O)NCCC[S+](C)C)cs2)cs1)C(C)O)C(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(OC(N)=O)C1O)c1cnc[nH]1
Isomeric SMILES
CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O

Synonyms

  • Bleomicin
  • Bleocin
  • Bleomicina
  • Bleomycine
  • Bleomycins
  • Bleomycinum
  • NDC 0015-3010
  • Bleo
  • Blenamax
  • Bleomycin A(2)
  • Bleomycin B(2)
  • Bleomycin Hexal
  • Bleo-kyowa
  • Mack, Bleomycinum
  • BLM

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless to yellow powderexp.
Solubility
Colorless or yellowish powder which becomes bluish depending on copper content. Very sol in water, methanol, practically insol in acetone, ethyl acetate, butyl acetate, ether, slightly sol in ethanol. /Bleomycins/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,415.58 g/molcalc.
Exact mass
1,414.5184 Dacalc.
LogP (octanol/water)
-7.7calc.
Topological polar surface area
627.1 Ųcalc.
Hydrogen bond donors
20calc.
Hydrogen bond acceptors
31calc.
Rotatable bonds
35calc.
Heavy atoms
96calc.
Rings
6calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.62calc.
Formal charge
1calc.
Stereocentres
19calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCCNC(=O)C(NC(=O)c1ccncn1)C(OC1OCCCC1OC1CCCCO1)c1cnc[nH]1)NCC(=O)NCCc1nc(-c2nccs2)cs1

O=C(CCCNC(=O)C(NC(=O)c1ccncn1)C(OC1OCCCC1OC1CCCCO1)c1cnc[nH]1)NCC(=O)NCCc1nc(-c2nccs2)cs1

6 rings, 55 atoms.

45 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Bleomycin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 18 suppliers
18 of 18 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

18 suppliers in 5 countries

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Bleomycin price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

It functions as an antineoplastic and diagnostic agent. ... It induces rupture of DNA strands.

Therapeutic category: Antineoplastic (Bleomycins).

Antineoplastic antibiotic.

Industries and functions

Pharmacological actions

  • Antibiotics, Antineoplastic

Roles

  • anti-HIV agent
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • pharmaceutical

Functional uses

  • Pharmaceutical

Pharmacology

Bleomycin is a Cytoprotective Agent.

How it is made

A glycopeptide antibiotic produced by Streptomyces verticillus

A group of related glycopeptide antibiotics isolated from Streptomyces verticillus. Purification and sepn into bleomycins A and B and their components (Bleomycins)

Bleomycins ... are a group of antitumor antibiotics initially isolated from broths of Streptomyces verticillus. The fermentation product consists of approximately 12 different components clinically marketed as bleomycin. Each is a peptide with a low relative molecular mass (about 1500), all containing bleomycinic acid but differing in terminal alkylamine groups. The clinical product is approximately 60 - 70% bleomycin A2 ... and 20 - 30% bleomycin B2. Other analogs comprise about 5% of the total. (Bleomycins)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bleomycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bleomycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bleomycin, based on the data on this page

What is Bleomycin?

Bleomycin is a mixture of glycopeptide antineoplastic antibiotics isolated from the bacterium Streptomyces verticillus.

What is the CAS number of Bleomycin?

The CAS registry number of Bleomycin is 11056-06-7.

What is the molecular formula and weight of Bleomycin?

The molecular formula of Bleomycin is C55H84N17O21S3+ and its molar mass is 1,415.58 g/mol.

What is Bleomycin used for?

It functions as an antineoplastic and diagnostic agent. ... It induces rupture of DNA strands. Therapeutic category: Antineoplastic (Bleomycins). Antineoplastic antibiotic.

Is Bleomycin hazardous?

No GHS hazard classification for Bleomycin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Bleomycin?

Bleomycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bleomycin?

CompoundList lists 18 suppliers of Bleomycin in India, China, United States, Spain and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bleomycin in India?

7 suppliers in India list Bleomycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bleomycin?

Suppliers quote Bleomycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bleomycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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