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Glycosides and other natural products

Bleomycin sulfate

Also known as Blexane, Bleomycin sulphate, Bleolem

CAS 9041-93-4Formula C55H86N17O25S4+Molar mass 1,513.66 g/molEC 232-925-2
GHS signal word: Danger. Pictograms: Serious health hazard 29 suppliers listed Drug substance
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Bleomycin sulfate chemical structure, C55H86N17O25S4+, CAS 9041-93-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
9041-93-4
Formula
C55H86N17O25S4+
Molar mass
1,513.66 g/mol
EC number
232-925-2
HS code
294190
Category
Glycosides and other natural products

What is Bleomycin sulfate?

Plain description, key identifiers and synonyms

Bleomycin Sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA, these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2R,3S,4S,5R,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium, sulfuric acid
CAS number
9041-93-4 CAS number cross-checkedOther or deprecated CAS: 41432-97-7
EC number
232-925-2
Molecular formula
C55H86N17O25S4+
InChIKey
WUIABRMSWOKTOF-OYALTWQYSA-O
InChI
InChI=1S/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-;/m0./s1
Canonical SMILES
Cc1c(N)nc(C(CC(N)=O)NCC(N)C(N)=O)nc1C(=O)NC(C(=O)NC(C)C(O)C(C)C(=O)NC(C(=O)NCCc1nc(-c2nc(C(=O)NCCC[S+](C)C)cs2)cs1)C(C)O)C(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(OC(N)=O)C1O)c1cnc[nH]1.O=S(=O)(O)O
Isomeric SMILES
CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)O

Synonyms

  • Blexane
  • Bleomycin sulphate
  • Bleolem
  • BleMomycine
  • Bleomycin, sulfate (salt)
  • Bleomycin Sulfas
  • Bleomycini sulfas
  • BLEOcell
  • Oil Bleo
  • Bleomycins sulfate
  • BLEO cell
  • BLEO-cell
  • Bleo-S
  • Sulfate, Bleomycin
  • N-[3-(dimethylsulfonio)propyl]bleomycinamide (Bleomycin A2) and N-[4-(carbamimidoylamino)butyl]bleomycinamide (Bleomycin B2)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,513.66 g/molcalc.
Exact mass
1,512.4858 Dacalc.
LogP (octanol/water)
-8.36calc.
Topological polar surface area
701.7 Ųcalc.
Hydrogen bond donors
22calc.
Hydrogen bond acceptors
33calc.
Rotatable bonds
35calc.
Heavy atoms
101calc.
Rings
6calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.62calc.
Formal charge
1calc.
Stereocentres
19calc.
Components
2calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCCNC(=O)C(NC(=O)c1ccncn1)C(OC1OCCCC1OC1CCCCO1)c1cnc[nH]1)NCC(=O)NCCc1nc(-c2nccs2)cs1

O=C(CCCNC(=O)C(NC(=O)c1ccncn1)C(OC1OCCCC1OC1CCCCO1)c1cnc[nH]1)NCC(=O)NCCc1nc(-c2nccs2)cs1

6 rings, 55 atoms.

45 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H340May cause genetic defects.
  • H351Suspected of causing cancer.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bleomycin sulfate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 29 suppliers
29 of 29 offers

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Where suppliers are based

29 suppliers in 9 countries

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Bleomycin sulfate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bleomycin sulfate is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bleomycin sulfate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bleomycin sulfate, based on the data on this page

What is Bleomycin sulfate?

Bleomycin Sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus.

What is the CAS number of Bleomycin sulfate?

The CAS registry number of Bleomycin sulfate is 9041-93-4. Other or deprecated CAS numbers: 41432-97-7.

What is the molecular formula and weight of Bleomycin sulfate?

The molecular formula of Bleomycin sulfate is C55H86N17O25S4+ and its molar mass is 1,513.66 g/mol.

What is Bleomycin sulfate used for?

Known uses and roles of Bleomycin sulfate include antineoplastic agent and pharmaceutical.

Is Bleomycin sulfate hazardous?

Bleomycin sulfate carries the GHS signal word "Danger". Main hazards: may cause genetic defects, suspected of causing cancer, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bleomycin sulfate?

Bleomycin sulfate is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bleomycin sulfate?

CompoundList lists 29 suppliers of Bleomycin sulfate in China, United States, India, Spain and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bleomycin sulfate in India?

3 suppliers in India list Bleomycin sulfate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bleomycin sulfate?

Suppliers quote Bleomycin sulfate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bleomycin sulfate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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