Bromocriptine
Also known as Bromoergocryptine, Bromocriptin, Bromoergocriptine
Key facts
What buyers check first
- CAS number
- 25614-03-3
- Formula
- C32H40BrN5O5
- Molar mass
- 654.61 g/mol
- EC number
- 247-128-5
- HS code
- 293969
- Category
- Central nervous system drugs
What is Bromocriptine?
Plain description, key identifiers and synonyms
Bromocriptine is an indole alkaloid. It has a role as an antiparkinson drug, a hormone antagonist, a dopamine agonist and an antidyskinesia agent. It derives from a hydride of an ergotaman.
Bromocriptine is a medication which has significant effects on dopamine levels in the brain.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (6aR,9R)-5-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
- CAS number
- 25614-03-3 CAS number cross-checked
- EC number
- 247-128-5
- Molecular formula
- C32H40BrN5O5
- UNII
- 3A64E3G5ZO
- InChIKey
- OZVBMTJYIDMWIL-AYFBDAFISA-N
- InChI
- InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1
- Canonical SMILES
- CC(C)CC1C(=O)N2CCCC2C2(O)OC(NC(=O)C3C=C4c5cccc6[nH]c(Br)c(c56)CC4N(C)C3)(C(C)C)C(=O)N12
- Isomeric SMILES
- CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O
Synonyms
- Bromoergocryptine
- Bromocriptin
- Bromoergocriptine
- Bromergocryptine
- 2-Bromo-alpha-ergocryptine
- Bromocriptina
- 2-Bromo-alpha-ergokryptin
- 2-Bromo-alpha-ergokryptine
- Bromocriptinum
- Ergoset
- Ergocryptine, 2-bromo-
- 2-Bromoergocryptine
- (+)-Bromocriptine
- Sandoz 15-754
- Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'alpha)-
- (5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trioxoergotaman
- (5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione
- Bromocryptin
- (5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman
- 2-Bromoergokryptine
- 2 Bromo alpha ergocryptine
- 2 Bromoergocryptine
- 2 Bromoergokryptine
- 2 Bromo alpha ergokryptine
- Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'alpha-(2-methylpropyl)-
Show all 33 synonymsShow fewer synonyms
- Bromocryptine
- Bromocriptine (mesylate)
- Bromergon
- CB 154
- Bromocriptine (USAN/INN)
- Bromokryptine
- 2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-alpha-(2-methylpropyl)ergotamin-3',6',18-trione
- Bromocriptine+ (GTP-)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 654.61 g/molcalc.Computed value |
|---|---|
| Exact mass | 653.2213 Dacalc.Computed value |
| LogP (octanol/water) | 3.19calc.Computed value |
| Topological polar surface area | 118.2 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 43calc.Computed value |
| Rings | 7calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.59calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 6calc.Computed value |
| Lipinski rule of five | Passes (1 violation)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C(NC1OC2C3CCCN3C(=O)CN2C1=O)C1C=C2c3cccc4[nH]cc(c34)CC2NC1
7 rings, 33 atoms.
61 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H361Suspected of damaging fertility or the unborn child.
- H362May cause harm to breast-fed children.
Precautionary statements (11)
- P203Obtain, read and follow all safety instructions before use.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P263Avoid contact during pregnancy and while nursing.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P318If exposed or concerned, get medical advice.
- P330Rinse mouth.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidBromocriptine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Netherlands, OldenzaalUnclaimed profileBromergocryptineGrade, purity and minimum order on requestPrice on request
- Bangladesh, Dhaka ManufacturerUnclaimed profileBromocriptineGrade, purity and minimum order on requestPrice on request
- Syria, Aleppo ManufacturerUnclaimed profileBromocriptinGrade, purity and minimum order on requestPrice on request
- Pakistan, Rawalpindi ManufacturerUnclaimed profileBromocriptineGrade, purity and minimum order on requestPrice on request
- India, Hyderabad ManufacturerUnclaimed profileBromocriptineGrade, purity and minimum order on requestPrice on request
- Price on request
- Price on request
- India, MumbaiUnclaimed profileBromocriptineGrade, purity and minimum order on requestPrice on request
- Poland, Warszawa ManufacturerUnclaimed profileBromocriptineGrade, purity and minimum order on requestPrice on request
- Price on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
39 suppliers in 16 countries
- China13
- United States8
- India4
- Netherlands2
- Bangladesh1
- Canada1
- and 10 more countries
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Bromocriptine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Antiparkinson Agents
- Dopamine Agonists
- Hormone Antagonists
Roles
- antagonist
- anti-obesity agent
- antidyskinesia agent
- antiparkinson drug
- appetite enhancer
- appetite regulator
- dopamine agonist
- dopaminergic agent
- hormone antagonist
- hormone receptor modulator
- hypoglycemic agent
- neurotransmitter agent
- pharmaceutical
- receptor modulator
Pharmacology
Bromocriptine is an Ergot Derivative.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Bromocriptine is traded under.
Alkaloids of rye ergot and their derivatives, salts thereof, other
- Czech Republic62.5%
- Italy14.4%
- United States3.7%
- Japan25.8%
- China11.3%
- United States7.5%
The HS code shown for Bromocriptine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Bromocriptine, based on the data on this page
What is Bromocriptine?
What is the CAS number of Bromocriptine?
What is the molecular formula and weight of Bromocriptine?
What is Bromocriptine used for?
Is Bromocriptine hazardous?
What is the HS code of Bromocriptine?
Where can I buy Bromocriptine?
Where can I buy Bromocriptine in India?
What is the price of Bromocriptine?
Guides for buyers
Practical guides that help when you source, ship or handle Bromocriptine
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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