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Heterocyclic compounds

Capreomycin

Also known as Capostatin, Capreomicin, Capreomicina

CAS 11003-38-6Formula C50H88N28O15Molar mass 1,321.44 g/mol
4 suppliers listed
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Capreomycin chemical structure, C50H88N28O15, CAS 11003-38-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
11003-38-6
Formula
C50H88N28O15
Appearance
White solid
Solubility
WHITE TO SLIGHTLY YELLOWISH WHITE, AMORPHOUS POWDER. ODORLESS. FREELY SOL IN WATER. PRAC…
HS code
294190
Category
Heterocyclic compounds
Illustrative photo, a white jumbo bulk bag of powder in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Capreomycin?

Plain description, key identifiers and synonyms

Capreomycin is a cyclic polypeptide isolated from Streptomyces capreolus with antitubercular activity. Even though the exact mechanism by which capreomycin exerts its effect has yet to be fully elucidated, this agent may bind to the bacterial 50S subunit of the 70S ribosome. This leads to interference with the translational initiation complex, misreading of mRNA, and eventually leads to inhibition of protein synthesis. In addition, capreomycin also binds bacterial cell wall components thereby inhibiting cell wall synthesis.

Capreomycin is a pharmaceutical drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(6R)-2-amino-1,4,5,6-tetrahydropyrimidin-6-yl]-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide, (3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(6R)-2-amino-1,4,5,6-tetrahydropyrimidin-6-yl]-8-[(carbamoylamino)methylidene]-2-methyl-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide
CAS number
11003-38-6 CAS number cross-checked
Molecular formula
C50H88N28O15
InChIKey
VCOPTHOUUNAYKQ-WBTCAYNUSA-N
InChI
InChI=1S/C25H44N14O8.C25H44N14O7/c26-4-1-2-11(27)6-17(41)32-8-14-20(43)35-15(9-34-25(30)47)21(44)39-18(13-3-5-31-24(29)38-13)23(46)33-7-12(28)19(42)37-16(10-40)22(45)36-14;1-11-19(41)36-15(9-32-17(40)7-12(27)3-2-5-26)21(43)37-16(10-34-25(30)46)22(44)39-18(14-4-6-31-24(29)38-14)23(45)33-8-13(28)20(42)35-11/h9,11-14,16,18,40H,1-8,10,26-28H2,(H,32,41)(H,33,46)(H,35,43)(H,36,45)(H,37,42)(H,39,44)(H3,29,31,38)(H3,30,34,47);10-15,18H,2-9,26-28H2,1H3,(H,32,40)(H,33,45)(H,35,42)(H,36,41)(H,37,43)(H,39,44)(H3,29,31,38)(H3,30,34,46)/b15-9+;16-10+/t11-,12-,13+,14-,16-,18-;11-,12-,13-,14+,15-,18-/m00/s1
Canonical SMILES
CC1NC(=O)C(N)CNC(=O)C(C2CCN=C(N)N2)NC(=O)C(=CNC(N)=O)NC(=O)C(CNC(=O)CC(N)CCCN)NC1=O.NCCCC(N)CC(=O)NCC1NC(=O)C(CO)NC(=O)C(N)CNC(=O)C(C2CCN=C(N)N2)NC(=O)C(=CNC(N)=O)NC1=O
Isomeric SMILES
C[C@H]1C(=O)N[C@H](C(=O)N/C(=C/NC(=O)N)/C(=O)N[C@H](C(=O)NC[C@@H](C(=O)N1)N)[C@H]2CCN=C(N2)N)CNC(=O)C[C@H](CCCN)N.C1CN=C(N[C@H]1[C@H]2C(=O)NC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N/C(=C/NC(=O)N)/C(=O)N2)CNC(=O)C[C@H](CCCN)N)CO)N)N

Synonyms

  • Capostatin
  • Capreomicin
  • Capreomicina
  • Capreomycine
  • Capromycin
  • Capreomycin Complex
  • Capastat
  • Capreomycinum
  • Kapreomycin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White solidexp.
Solubility
WHITE TO SLIGHTLY YELLOWISH WHITE, AMORPHOUS POWDER. ODORLESS. FREELY SOL IN WATER. PRACTICALLY INSOL IN MOST ORG SOLVENTS. /STERILE SULFATE SALT/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,321.44 g/molcalc.
Exact mass
1,320.6984 Dacalc.
LogP (octanol/water)
-15.44calc.
Topological polar surface area
736.6 Ųcalc.
Hydrogen bond donors
27calc.
Hydrogen bond acceptors
27calc.
Rotatable bonds
19calc.
Heavy atoms
93calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
12calc.
Components
2calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C=C1NC(=O)CNC(=O)CNC(=O)CCNC(=O)C(C2CCN=CN2)NC1=O

C=C1NC(=O)CNC(=O)CNC(=O)CCNC(=O)C(C2CCN=CN2)NC1=O

2 rings, 28 atoms.

35 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Capreomycin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 2 countries

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Capreomycin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Active against strains of Mycobacterium tuberculosis found in humans.

Therapeutic category: Antibacterial (tuberculostatic).

Second-line injectable anti-tuberculosis drug.

Pharmacological actions

  • Anti-Bacterial Agents
  • Antibiotics, Antitubercular
  • Protein Synthesis Inhibitors

Pharmacology

Capreomycin is an Antimycobacterial.

How it is made

Produced by Streptomyces capreolus

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Capreomycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Capreomycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Capreomycin, based on the data on this page

What is Capreomycin?

Capreomycin is a cyclic polypeptide isolated from Streptomyces capreolus with antitubercular activity. Even though the exact mechanism by which capreomycin exerts its effect has yet to be fully elucidated, this agent may bind to the bacterial 50S subunit of the 70S ribosome.

What is the CAS number of Capreomycin?

The CAS registry number of Capreomycin is 11003-38-6.

What is the molecular formula and weight of Capreomycin?

The molecular formula of Capreomycin is C50H88N28O15 and its molar mass is 1,321.44 g/mol.

What is Capreomycin used for?

Active against strains of Mycobacterium tuberculosis found in humans. Therapeutic category: Antibacterial (tuberculostatic). Second-line injectable anti-tuberculosis drug.

Is Capreomycin hazardous?

No GHS hazard classification for Capreomycin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Capreomycin?

Capreomycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Capreomycin?

CompoundList lists 4 suppliers of Capreomycin in Australia and India. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Capreomycin in India?

1 supplier in India list Capreomycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Capreomycin?

Suppliers quote Capreomycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Capreomycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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