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Carmustine chemical structure, C5H9Cl2N3O2, CAS 154-93-8
2D chemical structure

Key facts

What buyers check first

Appearance
Light yellow powder
Melting point
31 °C
Solubility
Highly soluble in alcohol and poorly soluble in water. It is also highly soluble in lipids
HS code
292419
Category
Oncology and immunology drugs
UN number
UN 2811
Illustrative photo, off-white crystalline powder in an HDPE jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Carmustine?

Plain description, key identifiers and synonyms

Carmustine is a member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group. It has a role as an alkylating agent and an antineoplastic agent. It is an organochlorine compound and a member of N-nitrosoureas.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,3-bis(2-chloroethyl)-1-nitrosourea
CAS number
154-93-8 CAS number cross-checked
EC number
205-838-2
Molecular formula
C5H9Cl2N3O2
UNII
U68WG3173Y
MDL number
MFCD00057706
InChIKey
DLGOEMSEDOSKAD-UHFFFAOYSA-N
InChI
InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
SMILES (canonical and isomeric)
C(CCl)NC(=O)N(CCCl)N=O

Synonyms

  • 1,3-Bis(2-chloroethyl)-1-nitrosourea
  • BCNU
  • Carmustin
  • Nitrumon
  • Carmubris
  • BiCNU
  • Becenun
  • Bischloroethyl nitrosourea
  • Carmustina
  • Carmustinum
  • Bischlorethylnitrosurea
  • N,N'-Bis(2-chloroethyl)-N-nitrosourea
  • Bischlorethylnitrosourea
  • Becenum
  • Urea, N,N'-bis(2-chloroethyl)-N-nitroso-
  • FIVB
  • Bischloroethylnitrosourea
  • FDA 0345
  • SRI 1720
  • SK 27702
  • Camustine
  • Carustine
  • 1,3-Bis(beta-chloroethyl)-1-nitrosourea
  • 1,3-bis(2-chloroethyl)-3-nitrosourea
  • Urea, 1,3-bis(2-chloroethyl)-1-nitroso-
Show all 38 synonyms
  • bis-chloroethylnitrosourea
  • Nitrourean
  • bis(chloroethyl) nitrosourea
  • Bis-Chloronitrosourea
  • Gliadel
  • 1,3-Bis(2-chloroethyl)nitrosourea
  • Bi CNU
  • Bis(2-chloroethyl)nitrosourea
  • BiCNU (TN)
  • Carmustine (98%)
  • Bis(chloroethyl)nitrosourea
  • DTI 015
  • Bis-N,N'-(chloroethyl)nitrosourea

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Light yellow powderexp.
Melting point
31 °Cexp.
Solubility
Highly soluble in alcohol and poorly soluble in water. It is also highly soluble in lipidsexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
214.05 g/molcalc.
Exact mass
213.0072 Dacalc.
LogP (octanol/water)
1.16calc.
Topological polar surface area
61.77 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
5calc.
Heavy atoms
12calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.8calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H300Fatal if swallowed.
  • H350May cause cancer.
  • H360May damage fertility or the unborn child.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2811

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Carmustine suppliers

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All 130 suppliers
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Where suppliers are based

130 suppliers in 17 countries

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Carmustine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Medication to treat cancer of the lymph system, cancerous brain tumors, and a certain type of bone marrow cancer.

Therapeutic category: Antineoplastic.

Industries and functions

Pharmacological actions

  • Antineoplastic Agents, Alkylating

Roles

  • aetiopathogenetic role
  • alkylating agent
  • anti-inflammatory agent
  • antineoplastic agent
  • genotoxin
  • immunomodulator
  • immunosuppressive agent
  • mutagen
  • pharmaceutical

Pharmacology

Carmustine is an Alkylating Drug. The mechanism of action of carmustine is as an Alkylating Activity.

How it is made

/Carmustine/ may be synthesized by nitrosation with sodium nitrite of the appropriate substituted uera - in this case 1,3-bis(2-chloroethyl)urea - in a cold, acid medium (e.g., formic acid).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Carmustine is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Carmustine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Carmustine, based on the data on this page

What is Carmustine?

Carmustine is a member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group. It has a role as an alkylating agent and an antineoplastic agent. It is an organochlorine compound and a member of N-nitrosoureas.

What is the CAS number of Carmustine?

The CAS registry number of Carmustine is 154-93-8.

What is the molecular formula and weight of Carmustine?

The molecular formula of Carmustine is C5H9Cl2N3O2 and its molar mass is 214.05 g/mol.

What is Carmustine used for?

Medication to treat cancer of the lymph system, cancerous brain tumors, and a certain type of bone marrow cancer. Therapeutic category: Antineoplastic.

Is Carmustine hazardous?

Carmustine carries the GHS signal word "Danger". Main hazards: fatal if swallowed, may cause cancer, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Carmustine?

Carmustine is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Carmustine?

CompoundList lists 130 suppliers of Carmustine in China, United States, India, Germany and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Carmustine in India?

16 suppliers in India list Carmustine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Carmustine?

Suppliers quote Carmustine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Carmustine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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