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Alkaloids

Cathine

Also known as Pseudonorephedrine, (+)-Norpseudoephedrine, Katine

CAS 492-39-7Formula C9H13NOMolar mass 151.21 g/molEC 207-754-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant Prohibited, not for trade
Why it is not for trade
Cathine chemical structure, C9H13NO, CAS 492-39-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
492-39-7
Formula
C9H13NO
Molar mass
151.21 g/mol
EC number
207-754-1
HS code
293943
Category
Alkaloids

What is Cathine?

Plain description, key identifiers and synonyms

Cathine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2S-stereoisomer). It has a role as a central nervous system stimulant, a psychotropic drug and a plant metabolite. It is a member of amphetamines and a phenethylamine alkaloid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1S,2S)-2-amino-1-phenylpropan-1-ol
CAS number
492-39-7 CAS number cross-checkedOther or deprecated CAS: 36393-56-3
EC numbers
207-754-1, 253-014-6
Molecular formula
C9H13NO
UNII
27A0HLC3HH, E1L4ZW2F8O
InChIKey
DLNKOYKMWOXYQA-IONNQARKSA-N
InChI
InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9+/m0/s1
Canonical SMILES
CC(N)C(O)c1ccccc1
Isomeric SMILES
C[C@@H]([C@H](C1=CC=CC=C1)O)N

Synonyms

  • Pseudonorephedrine
  • (+)-Norpseudoephedrine
  • Katine
  • D-Cathine
  • Cathinum
  • d-Norpseudoephedrine
  • psi-Norephedrine
  • (1S,2S)-2-amino-1-phenylpropan-1-ol
  • d-Nor-psi-ephedrine
  • (1S,2S)-Pseudonorephedrine
  • Norpseudoephedrine, d-
  • threo-1-Phenyl-1-hydroxy-2-aminopropane
  • threo-2-Amino-1-hydroxy-1-phenylpropane
  • D-(+)-Norpseudoephedrine
  • (1S,2S)-2-amino-1-phenyl-propan-1-ol
  • threo-2-Amino-1-phenylpropan-1-ol
  • Benzenemethanol, alpha-((1S)-1-aminoethyl)-, (alphaS)-
  • (1S,2S)-(+)-norpseudoephedrine
  • omega-norephedrine
  • Phenylpropanolamine d-threo-
  • Exponcit
  • Minusine
  • Norpseudoephedrine
  • Racemic norpseudoephedrine
  • d-Phenylpropanolamine
Show all 36 synonyms
  • Catina
  • dl-Nor-psi-ephedrine
  • (+)-Norephedrin
  • D-(+)-Norephedrine
  • Norpseudoephedrine, (+-)-
  • (1S,2S)-2-amino-1-phenyl-1-propanol
  • NIOSH/RC9110000
  • Cathine (INN)
  • l-Nor-psi-ephedrine
  • l-Nor-psi-ephedrin
  • Cathina

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
151.21 g/molcalc.
Exact mass
151.0997 Dacalc.
LogP (octanol/water)
1.07calc.
Topological polar surface area
46.25 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301Toxic if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cathine suppliers

Trading restrictions apply to this substance

Psychotropic substance

Cathine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2939.43 (cathine)

Our policy on controlled substances

Cathine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Roles

  • anti-obesity agent
  • central nervous system drug
  • central nervous system stimulant
  • eukaryotic metabolite
  • metabolite
  • pharmaceutical
  • plant metabolite
  • psychotropic drug

Functional uses

  • Pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Cathine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2939.43 (cathine)

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled psychotropic substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cathine is traded under.

HS 2939.43Exact HS code

Cathine (INN) and its salts

World exports in 2024
$125K
+1295% vs 2023, imports $77.8K
2019 to 2024
Top exporters
  1. United States84.4%
  2. Germany8.1%
  3. Spain3.5%
Top importers
  1. Egypt89.2%
  2. France * partner reported7.0%
  3. Romania1.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cathine is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cathine, based on the data on this page

What is Cathine?

Cathine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2S-stereoisomer). It has a role as a central nervous system stimulant, a psychotropic drug and a plant metabolite. It is a member of amphetamines and a phenethylamine alkaloid.

What is the CAS number of Cathine?

The CAS registry number of Cathine is 492-39-7. Other or deprecated CAS numbers: 36393-56-3.

What is the molecular formula and weight of Cathine?

The molecular formula of Cathine is C9H13NO and its molar mass is 151.21 g/mol.

What is Cathine used for?

Use classes: Pharmaceuticals.

Is Cathine hazardous?

Cathine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cathine?

Cathine is usually classified under HS code 293943 (Cathine (INN) and its salts). This is indicative, confirm it with your customs broker before shipping.

Can I buy Cathine on CompoundList?

No. Cathine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Cathine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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