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Pharmaceuticals and APIs

Cevimeline

Also known as cevimelina, cevimelinum, Sni 2011

CAS 107233-08-9Formula C10H17NOSMolar mass 199.32 g/mol
8 suppliers listed Drug substance
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Cevimeline chemical structure, C10H17NOS, CAS 107233-08-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
107233-08-9
Formula
C10H17NOS
Melting point
201 to 203 °C
Solubility
In water, 4.1 × 10⁺⁴ mg/L at 25 °C /Estimated/
HS code
293499
Category
Pharmaceuticals and APIs

What is Cevimeline?

Plain description, key identifiers and synonyms

Cevimeline is a member of quinuclidines and an oxathiolane. It has a role as a muscarinic agonist.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane]
CAS number
107233-08-9 CAS number cross-checkedOther or deprecated CAS: 112425-76-0, 1933761-49-9
Molecular formula
C10H17NOS
InChIKey
WUTYZMFRCNBCHQ-LHIURRSHSA-N
InChI
InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8?,10-/m1/s1
Canonical SMILES
CC1OC2(CS1)CN1CCC2CC1
Isomeric SMILES
CC1O[C@]2(CN3CCC2CC3)CS1

Synonyms

  • cevimelina
  • cevimelinum
  • Sni 2011
  • 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine
  • (2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane]
  • (2R)-5'-methyl-4-azaspiro(bicyclo(2.2.2)octane-2,2'-(1,4)oxathiolane)
  • Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, (2'R,3R)-rel-
  • Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, cis-
  • AF102B (hydrochloride)
  • Cevimeline, hydrochloridesalt
  • (2R)-2'-methylspiro[4-quinuclidine -2,5'-[1,3]oxathiolane]
  • (2R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]
  • Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)-rel-
  • rel-(+)-(2a(2)R,3R)-2a(2)-Methylspiro[1-azabicyclo[2.2.2]octane-3,5a(2)-[1,3]oxathiolane]

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Melting point
201 to 203 °Cexp.
Solubility
In water, 4.1 × 10⁺⁴ mg/L at 25 °C /Estimated/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
199.32 g/molcalc.
Exact mass
199.1031 Dacalc.
LogP (octanol/water)
1.56calc.
Topological polar surface area
12.47 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
13calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1OC2(CS1)CN1CCC2CC1

C1OC2(CS1)CN1CCC2CC1

4 rings, 12 atoms.

20 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Cevimeline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 5 countries

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Cevimeline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

The safety and efficacy of cevimeline for the treatment of dementia of Alzheimer's disease has not been established.

Pharmacological actions

  • Muscarinic Agonists
  • Parasympathomimetics

Roles

  • cholinergic agonist
  • cholinergic drug
  • muscarinic agonist
  • neurotransmitter agent
  • pharmaceutical

Pharmacology

Cevimeline is a Cholinergic Receptor Agonist. The mechanism of action of cevimeline is as a Cholinergic Muscarinic Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cevimeline is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Cevimeline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cevimeline, based on the data on this page

What is Cevimeline?

Cevimeline is a member of quinuclidines and an oxathiolane. It has a role as a muscarinic agonist.

What is the CAS number of Cevimeline?

The CAS registry number of Cevimeline is 107233-08-9. Other or deprecated CAS numbers: 112425-76-0, 1933761-49-9.

What is the molecular formula and weight of Cevimeline?

The molecular formula of Cevimeline is C10H17NOS and its molar mass is 199.32 g/mol.

What is Cevimeline used for?

The safety and efficacy of cevimeline for the treatment of dementia of Alzheimer's disease has not been established.

Is Cevimeline hazardous?

No GHS hazard classification for Cevimeline is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Cevimeline?

Cevimeline is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cevimeline?

CompoundList lists 8 suppliers of Cevimeline in India, China, Japan, Poland and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Cevimeline in India?

3 suppliers in India list Cevimeline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Cevimeline?

Suppliers quote Cevimeline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cevimeline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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