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Screening compounds

Cilomilast

Also known as Ariflo, trans-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid, SB 207499

CAS 153259-65-5Formula C20H25NO4Molar mass 343.42 g/mol
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Cilomilast chemical structure, C20H25NO4, CAS 153259-65-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
153259-65-5
Formula
C20H25NO4
Molar mass
343.42 g/mol
HS code
292690
Category
Screening compounds

What is Cilomilast?

Plain description, key identifiers and synonyms

4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)-1-cyclohexanecarboxylic acid is a member of methoxybenzenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexane-1-carboxylic acid
CAS number
153259-65-5 CAS number cross-checkedOther or deprecated CAS: 153259-69-9, 164414-71-5, 1794779-92-2
Molecular formula
C20H25NO4
UNII
8ATB1C1R6X
MDL number
MFCD28044030
InChIKey
CFBUZOUXXHZCFB-UHFFFAOYSA-N
InChI
InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)
SMILES (canonical and isomeric)
COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3

Synonyms

  • Ariflo
  • trans-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid
  • SB 207499
  • cis-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid
  • Cilomilast-d9
  • 4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexane-1-carboxylic acid
  • cis-4-Cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid
  • (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid
  • 4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid
  • CIO
  • 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid
  • (1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid
  • Cyclohexanecarboxylic acid, 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, cis-
  • rel-(1s,4s)-4-Cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid
  • Ariflo (TN)
  • Cilomilast (JAN/USAN/INN)
  • 1xlx
  • 1xom
  • (1s,4s)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid
  • Cyclohexanecarboxylic acid, 4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, cis-
  • cis-4-Cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexanecarboxylic acid
  • cis-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-4-cyanocyclohexane-1-carboxylic acid
  • Cyclohexanecarboxylic acid,4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, trans-
  • Cilomilast, SB 207499, Ariflo
  • PDSP1_001287
Show all 29 synonyms
  • PDSP2_001271
  • 4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)cyclohexane-1-carboxylic acid
  • cis-4-Cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexan
  • 6-(3,4-Dimethoxy-phenyl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
343.42 g/molcalc.
Exact mass
343.1784 Dacalc.
LogP (octanol/water)
4.05calc.
Topological polar surface area
79.55 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
5calc.
Heavy atoms
25calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1cc(OC2CCCC2)cc(C2CCCCC2)c1

c1cc(OC2CCCC2)cc(C2CCCCC2)c1

3 rings, 18 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Cilomilast suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 3 countries

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Cilomilast price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cilomilast is traded under.

HS 2926.90Indicative HS code

Nitrile-function compounds, other

World exports in 2024
$2.15B
−13.5% vs 2023, imports $2.17B
2019 to 2024
Top exporters
  1. China35.6%
  2. France * partner reported12.7%
  3. India * partner reported11.2%
Top importers
  1. United States13.6%
  2. China12.4%
  3. Brazil11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cilomilast is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cilomilast, based on the data on this page

What is Cilomilast?

4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)-1-cyclohexanecarboxylic acid is a member of methoxybenzenes.

What is the CAS number of Cilomilast?

The CAS registry number of Cilomilast is 153259-65-5. Other or deprecated CAS numbers: 153259-69-9, 164414-71-5, 1794779-92-2.

What is the molecular formula and weight of Cilomilast?

The molecular formula of Cilomilast is C20H25NO4 and its molar mass is 343.42 g/mol.

What is Cilomilast used for?

Known uses and roles of Cilomilast include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Cilomilast hazardous?

No GHS hazard classification for Cilomilast is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Cilomilast?

Cilomilast is usually classified under HS code 292690 (Nitrile-function compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cilomilast?

CompoundList lists 8 suppliers of Cilomilast in United States, China and Canada. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Cilomilast?

Suppliers quote Cilomilast on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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