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Sulfur and phosphorus compounds

Cyclosarin

Also known as Cyclohexyl methylphosphonofluoridate, CF Me ester, GF (chemical warfare agent)

CAS 329-99-7Formula C7H14FO2PMolar mass 180.16 g/mol
Prohibited, not for trade
Why it is not for trade
Cyclosarin chemical structure, C7H14FO2P, CAS 329-99-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless liquid
Melting point
-30 °C
Boiling point
239 °C
Density
1.13
Solubility
In water, 3,700 mg/L at 20 °C
HS code
293149
Category
Sulfur and phosphorus compounds

What is Cyclosarin?

Plain description, key identifiers and synonyms

G-Series Nerve Agent GF is a man-made highly toxic organic phosphate that is more persistent and less lethal than its nerve agent predecessor, Sarin. It is a colorless liquid with a sweet, musty odor that is rapidly absorbed through skin and inhibits acetylcholinesterase, increasing the neurotransmitter acetylcholine at central and peripheral neuronal synapses.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[fluoro(methyl)phosphoryl]oxycyclohexane
CAS number
329-99-7 CAS number cross-checked
Molecular formula
C7H14FO2P
UNII
VM36F9N236
InChIKey
SNTRKUOVAPUGAY-UHFFFAOYSA-N
InChI
InChI=1S/C7H14FO2P/c1-11(8,9)10-7-5-3-2-4-6-7/h7H,2-6H2,1H3
SMILES (canonical and isomeric)
CP(=O)(OC1CCCCC1)F

Synonyms

  • Cyclohexyl methylphosphonofluoridate
  • CF Me ester
  • GF (chemical warfare agent)
  • O-Cyclohexyl methylphosphonofluoridate
  • Methyl cyclohexylfluorophosphonate
  • Cyclosin (chemical warfare agent)
  • EA 1212
  • Phosphonofluoridic acid, methyl-, cyclohexyl ester
  • CMPF ester
  • GF cpd
  • cyclohexylmethylphosphonofluoridate
  • g-Series nerve agent gf
  • [fluoro(methyl)phosphoryl]oxycyclohexane
  • Cyclohexyl methylphosphonofluoridoate #
  • Cyclohexyl methylphosphonofluoridate (GF)
  • Methylphosphonic acid, fluoroanhydride, cyclohexyl ester

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless liquidexp.
Odour
Odorlessexp.
Melting point
-30 °Cexp.
Boiling point
239 °Cexp.
Density
1.13exp.
Solubility
In water, 3,700 mg/L at 20 °Cexp.
Vapour pressure
0.044 mm Hg at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
180.16 g/molcalc.
Exact mass
180.0715 Dacalc.
LogP (octanol/water)
3.13calc.
Topological polar surface area
26.3 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCCCC1

C1CCCCC1

1 ring, 6 atoms, the Cyclohexane ring system.

24,737 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Cyclosarin suppliers

Trading restrictions apply to this substance

Chemical Weapons Convention Schedule 1

Cyclosarin is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: OPCW Chemical Weapons Convention Schedule 1

Our policy on controlled substances

Cyclosarin price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Chemical warfare nerve agent.

How it is made

Derived from phosphoramidocyanidic or methylphosphonofluoridic acid

Regulatory status

Inventories, regulations and trade controls that list this substance

Chemical Weapons Convention Schedule 1

Cyclosarin is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: OPCW Chemical Weapons Convention Schedule 1

Our policy on controlled substances

Controls

  • Chemical Weapons Convention Schedule 1

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cyclosarin is traded under.

HS 2931.49Indicative HS code

Non-halogenated organo-phosphorous derivatives, other

World exports in 2024
$3.44B
−6.5% vs 2023, imports $3.07B
2022 to 2024
Top exporters
  1. China54.9%
  2. United States25.4%
  3. Germany5.1%
Top importers
  1. United States20.9%
  2. Argentina14.9%
  3. Brazil14.3%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Cyclosarin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cyclosarin, based on the data on this page

What is Cyclosarin?

G-Series Nerve Agent GF is a man-made highly toxic organic phosphate that is more persistent and less lethal than its nerve agent predecessor, Sarin.

What is the CAS number of Cyclosarin?

The CAS registry number of Cyclosarin is 329-99-7.

What is the molecular formula and weight of Cyclosarin?

The molecular formula of Cyclosarin is C7H14FO2P and its molar mass is 180.16 g/mol.

What is Cyclosarin used for?

Chemical warfare nerve agent.

Is Cyclosarin hazardous?

No GHS hazard classification for Cyclosarin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Cyclosarin?

Cyclosarin is usually classified under HS code 293149 (Non-halogenated organo-phosphorous derivatives, other). This is indicative, confirm it with your customs broker before shipping.

Can I buy Cyclosarin on CompoundList?

No. Cyclosarin is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Cyclosarin

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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